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Aliases for OR8D2 Gene

Aliases for OR8D2 Gene

  • Olfactory Receptor, Family 8, Subfamily D, Member 2 (Gene/Pseudogene) 2 3
  • Olfactory Receptor-Like Protein JCG2 3 4
  • Olfactory Receptor OR11-303 3 4
  • Olfactory Receptor 8D2 3
  • JCG2 3

External Ids for OR8D2 Gene

Previous GeneCards Identifiers for OR8D2 Gene

  • GC11U990223
  • GC11M123727
  • GC11M123694
  • GC11M124189

Summaries for OR8D2 Gene

Entrez Gene Summary for OR8D2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8D2 Gene

OR8D2 (Olfactory Receptor, Family 8, Subfamily D, Member 2 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR8B8.

UniProtKB/Swiss-Prot for OR8D2 Gene

  • Odorant receptor (Potential). May be involved in taste perception.

Gene Wiki entry for OR8D2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8D2 Gene

Genomics for OR8D2 Gene

Regulatory Elements for OR8D2 Gene

Genomic Location for OR8D2 Gene

124,319,262 bp from pter
124,320,197 bp from pter
936 bases
Minus strand

Genomic View for OR8D2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR8D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8D2 Gene

Proteins for OR8D2 Gene

  • Protein details for OR8D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 8D2
    Protein Accession:
    Secondary Accessions:
    • B9EH49
    • Q6IFR0

    Protein attributes for OR8D2 Gene

    311 amino acids
    Molecular mass:
    34857 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8D2 Gene

Proteomics data for OR8D2 Gene at MOPED

Post-translational modifications for OR8D2 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR8D2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR8D2 Gene

Domains for OR8D2 Gene

Gene Families for OR8D2 Gene

Protein Domains for OR8D2 Gene

Suggested Antigen Peptide Sequences for OR8D2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8D2: view

Function for OR8D2 Gene

Molecular function for OR8D2 Gene

GENATLAS Biochemistry:
olfactory receptor,family 8,subfamily D,member 2,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor (Potential). May be involved in taste perception.

Gene Ontology (GO) - Molecular Function for OR8D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR8D2: view

Animal Model Products

CRISPR Products

miRNA for OR8D2 Gene

miRTarBase miRNAs that target OR8D2

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8D2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR8D2 Gene

Localization for OR8D2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8D2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR8D2 Gene COMPARTMENTS Subcellular localization image for OR8D2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR8D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR8D2: view

Pathways for OR8D2 Gene

genes like me logo Genes that share pathways with OR8D2: view

Pathways by source for OR8D2 Gene

1 KEGG pathway for OR8D2 Gene

Interacting Proteins for OR8D2 Gene

Gene Ontology (GO) - Biological Process for OR8D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR8D2: view

Transcripts for OR8D2 Gene

mRNA/cDNA for OR8D2 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8D2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR8D2 Gene

No ASD Table

Relevant External Links for OR8D2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR8D2 Gene

mRNA expression in normal human tissues for OR8D2 Gene

Protein differential expression in normal tissues for OR8D2 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR8D2 Gene

SOURCE GeneReport for Unigene cluster for OR8D2 Gene Hs.504212

mRNA Expression by UniProt/SwissProt for OR8D2 Gene

Tissue specificity: Expressed in the tongue
genes like me logo Genes that share expressions with OR8D2: view

Expression partners for OR8D2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for OR8D2 Gene

Orthologs for OR8D2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8D2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC100301297 35
  • 85.93 (n)
  • 84.09 (a)
OR8D2 36
  • 83 (a)
(Mus musculus)
Mammalia Olfr924 35
  • 83.82 (n)
  • 85.34 (a)
Olfr924 16
Olfr924 36
  • 85 (a)
Olfr926 36
  • 82 (a)
(Pan troglodytes)
Mammalia LOC466829 35
  • 98.29 (n)
  • 96.78 (a)
OR8D2 36
  • 97 (a)
(Canis familiaris)
Mammalia OR8D2 36
  • 83 (a)
(Monodelphis domestica)
Mammalia OR8D2 36
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
Species with no ortholog for OR8D2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8D2 Gene

Gene Tree for OR8D2 (if available)
Gene Tree for OR8D2 (if available)

Paralogs for OR8D2 Gene

Paralogs for OR8D2 Gene

(450) SIMAP similar genes for OR8D2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR8D2: view

Variants for OR8D2 Gene

Sequence variations from dbSNP and Humsavar for OR8D2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs614013 -- 124,322,028(+) AATAA(C/T)GCCTA upstream-variant-2KB
rs665860 -- 124,318,911(+) GGCTT(C/G)TAATT downstream-variant-500B
rs677501 -- 124,319,178(+) CTCTC(C/G/T)GAGAG downstream-variant-500B
rs2466620 - 124,319,410(+) TGGAA(A/G)GGGGC reference, missense
rs2466621 -- 124,320,241(+) AAGAG(A/G)GACAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR8D2 Gene

Variant ID Type Subtype PubMed ID
nsv898435 CNV Gain 21882294
nsv826113 CNV Loss 20364138
nsv826115 CNV Loss 20364138

Relevant External Links for OR8D2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR8D2 Gene

Disorders for OR8D2 Gene

No disorders were found for OR8D2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR8D2 Gene

Publications for OR8D2 Gene

  1. New GPCRs from a human lingual cDNA library. (PMID: 11705801) Gaudin J.-C. … Haertle T. (Chem. Senses 2001) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. An investigation into the human serum "interactome". (PMID: 15174051) Zhou M. … Conrads T.P. (Electrophoresis 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR8D2 Gene

Sources for OR8D2 Gene

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