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Aliases for OR8B8 Gene

Aliases for OR8B8 Gene

  • Olfactory Receptor, Family 8, Subfamily B, Member 8 2 3
  • Olfactory-Like Receptor JCG8 3 4
  • Olfactory Receptor TPCR85 3 4
  • Olfactory Receptor OR11-316 3
  • Olfactory Receptor 8B8 3
  • TPCR85 3

External Ids for OR8B8 Gene

Previous GeneCards Identifiers for OR8B8 Gene

  • GC11M126311
  • GC11M125823
  • GC11M124343
  • GC11M123848
  • GC11M123163
  • GC11M123815

Summaries for OR8B8 Gene

Entrez Gene Summary for OR8B8 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8B8 Gene

OR8B8 (Olfactory Receptor, Family 8, Subfamily B, Member 8) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR8G5.

UniProtKB/Swiss-Prot for OR8B8 Gene

  • Odorant receptor (Potential). May be involved in taste perception.

Gene Wiki entry for OR8B8 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8B8 Gene

Genomics for OR8B8 Gene

Regulatory Elements for OR8B8 Gene

Genomic Location for OR8B8 Gene

124,440,126 bp from pter
124,441,158 bp from pter
1,033 bases
Minus strand

Genomic View for OR8B8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR8B8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8B8 Gene

Proteins for OR8B8 Gene

  • Protein details for OR8B8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 8B8
    Protein Accession:
    Secondary Accessions:
    • A1L446
    • Q96RC8

    Protein attributes for OR8B8 Gene

    311 amino acids
    Molecular mass:
    34482 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8B8 Gene

Proteomics data for OR8B8 Gene at MOPED

Post-translational modifications for OR8B8 Gene

Other Protein References for OR8B8 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR8B8 Gene

Domains for OR8B8 Gene

Gene Families for OR8B8 Gene

  • OR8 :GPCR / Class A : Olfactory receptors

Protein Domains for OR8B8 Gene

Suggested Antigen Peptide Sequences for OR8B8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q15620
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8B8: view

Function for OR8B8 Gene

Molecular function for OR8B8 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor (Potential). May be involved in taste perception.

Gene Ontology (GO) - Molecular Function for OR8B8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity NAS 9119360
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR8B8: view
genes like me logo Genes that share phenotypes with OR8B8: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8B8

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR8B8 Gene

Localization for OR8B8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8B8 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR8B8 Gene COMPARTMENTS Subcellular localization image for OR8B8 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR8B8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane NAS 9119360
genes like me logo Genes that share ontologies with OR8B8: view

Pathways for OR8B8 Gene

genes like me logo Genes that share pathways with OR8B8: view

Pathways by source for OR8B8 Gene

1 KEGG pathway for OR8B8 Gene

Interacting Proteins for OR8B8 Gene

Gene Ontology (GO) - Biological Process for OR8B8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 9119360
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9119360
genes like me logo Genes that share ontologies with OR8B8: view

Transcripts for OR8B8 Gene

mRNA/cDNA for OR8B8 Gene

(3) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8B8

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR8B8 Gene

No ASD Table

Relevant External Links for OR8B8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR8B8 Gene

mRNA expression in normal human tissues for OR8B8 Gene

SOURCE GeneReport for Unigene cluster for OR8B8 Gene Hs.351822

mRNA Expression by UniProt/SwissProt for OR8B8 Gene

Tissue specificity: Expressed in the tongue and testis
genes like me logo Genes that share expressions with OR8B8: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Expression partners for OR8B8 Gene

Orthologs for OR8B8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8B8 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR8B8 35
  • 88.17 (n)
  • 87.74 (a)
OR8B8 36
  • 86 (a)
(Canis familiaris)
Mammalia LOC489317 35
  • 87.53 (n)
  • 88.71 (a)
OR8B8 36
  • 87 (a)
(Mus musculus)
Mammalia Olfr145 35
  • 85.05 (n)
  • 86.45 (a)
Olfr145 16
Olfr145 36
  • 86 (a)
(Pan troglodytes)
Mammalia LOC100615359 35
  • 98.8 (n)
  • 98.45 (a)
(Rattus norvegicus)
Mammalia Olr1201 35
  • 85.59 (n)
  • 86.45 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
-- 36
  • 77 (a)
-- 36
  • 75 (a)
Species with no ortholog for OR8B8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8B8 Gene

Gene Tree for OR8B8 (if available)
Gene Tree for OR8B8 (if available)

Paralogs for OR8B8 Gene

Paralogs for OR8B8 Gene

Selected SIMAP similar genes for OR8B8 Gene using alignment to 1 proteins: Pseudogenes for OR8B8 Gene

genes like me logo Genes that share paralogs with OR8B8: view

Variants for OR8B8 Gene

Sequence variations from dbSNP and Humsavar for OR8B8 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1893135 -- 124,440,422(+) GGAGA(A/G)AATGA reference, missense
rs4296049 -- 124,440,726(+) CGGTC(A/G)TACGC synonymous-codon, reference
rs7103619 -- 124,442,511(+) ACCAA(C/T)CTGTC upstream-variant-2KB
rs7110330 -- 124,441,197(+) GCACA(C/G)AGAGA upstream-variant-2KB
rs7113677 -- 124,441,472(+) GACTT(C/T)CCAGA upstream-variant-2KB

Relevant External Links for OR8B8 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR8B8 Gene

Disorders for OR8B8 Gene

No disorders were found for OR8B8 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR8B8 Gene

Publications for OR8B8 Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 2 3 4
  2. New GPCRs from a human lingual cDNA library. (PMID: 11705801) Gaudin J.-C. … Haertle T. (Chem. Senses 2001) 3 4
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3

Products for OR8B8 Gene

Sources for OR8B8 Gene

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