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Aliases for OR7G2 Gene

Aliases for OR7G2 Gene

  • Olfactory Receptor, Family 7, Subfamily G, Member 2 2 3
  • Olfactory Receptor OR19-6 3 4
  • Olfactory Receptor 19-13 3 4
  • OR19-13 3 4
  • OST260 3 4
  • Olfactory Receptor 7G2 3
  • OR19-6 3

External Ids for OR7G2 Gene

Summaries for OR7G2 Gene

Entrez Gene Summary for OR7G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7G2 Gene

OR7G2 (Olfactory Receptor, Family 7, Subfamily G, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR7G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7G2 Gene

Genomics for OR7G2 Gene

Genomic Location for OR7G2 Gene

Start:
9,102,269 bp from pter
End:
9,103,306 bp from pter
Size:
1,038 bases
Orientation:
Minus strand

Genomic View for OR7G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7G2 Gene

Regulatory Elements for OR7G2 Gene

Proteins for OR7G2 Gene

  • Protein details for OR7G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NG99-OR7G2_HUMAN
    Recommended name:
    Olfactory receptor 7G2
    Protein Accession:
    Q8NG99
    Secondary Accessions:
    • Q6IFJ4
    • Q96RA0

    Protein attributes for OR7G2 Gene

    Size:
    324 amino acids
    Molecular mass:
    35931 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04666.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR7G2 Gene

Proteomics data for OR7G2 Gene at MOPED

Post-translational modifications for OR7G2 Gene

Other Protein References for OR7G2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR7G2 Gene

Domains for OR7G2 Gene

Gene Families for OR7G2 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7G2 Gene

UniProtKB/Swiss-Prot:

OR7G2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NG99
genes like me logo Genes that share domains with OR7G2: view

Function for OR7G2 Gene

Molecular function for OR7G2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7G2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR7G2 Gene

Localization for OR7G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7G2 Gene COMPARTMENTS Subcellular localization image for OR7G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7G2: view

Pathways for OR7G2 Gene

genes like me logo Genes that share pathways with OR7G2: view

Pathways by source for OR7G2 Gene

Interacting Proteins for OR7G2 Gene

Gene Ontology (GO) - Biological Process for OR7G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7G2: view

Transcripts for OR7G2 Gene

mRNA/cDNA for OR7G2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR7G2 Gene

No ASD Table

Relevant External Links for OR7G2 Gene

GeneLoc Exon Structure for
OR7G2
ECgene alternative splicing isoforms for
OR7G2

Expression for OR7G2 Gene

mRNA expression in normal human tissues for OR7G2 Gene

SOURCE GeneReport for Unigene cluster for OR7G2 Gene Hs.553774

genes like me logo Genes that share expressions with OR7G2: view

Orthologs for OR7G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7G2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR7G1 36
  • 82.25 (n)
  • 74.35 (a)
OR7G2 37
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR28G07 37
  • 76 (a)
OneToOne
OR7G2 36
  • 81.16 (n)
  • 76.19 (a)
mouse
(Mus musculus)
Mammalia Olfr828 37
  • 70 (a)
OneToMany
Olfr829 37
  • 68 (a)
OneToMany
Olfr830 37
  • 62 (a)
OneToMany
Olfr835 37
  • 68 (a)
OneToMany
Olfr836 37
  • 62 (a)
OneToMany
Olfr843 37
  • 62 (a)
OneToMany
Olfr844 37
  • 68 (a)
OneToMany
Olfr845 37
  • 72 (a)
OneToMany
Olfr846 37
  • 67 (a)
OneToMany
Olfr847 37
  • 65 (a)
OneToMany
Olfr849 37
  • 66 (a)
OneToMany
Olfr850 37
  • 70 (a)
OneToMany
Olfr851 37
  • 64 (a)
OneToMany
Olfr853 36
  • 72.35 (n)
  • 69.84 (a)
Olfr854 16
Olfr854 37
  • 72 (a)
OneToMany
Olfr855 37
  • 66 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr1145 36
  • 72.02 (n)
  • 67.87 (a)
Species with no ortholog for OR7G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7G2 Gene

ENSEMBL:
Gene Tree for OR7G2 (if available)
TreeFam:
Gene Tree for OR7G2 (if available)

Paralogs for OR7G2 Gene

Paralogs for OR7G2 Gene

Selected SIMAP similar genes for OR7G2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR7G2: view

Variants for OR7G2 Gene

Sequence variations from dbSNP and Humsavar for OR7G2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4804399 -- 9,102,188(+) CAGAG(A/C)AAGAC downstream-variant-500B
rs4804400 -- 9,102,350(+) GTTCC(C/T)TTCAT reference, synonymous-codon
rs4804401 - 9,102,403(+) AGGGA(A/C)CACAG missense, reference
rs7247751 -- 9,102,720(+) AGAGC(A/G)GGATT reference, missense
rs12608683 -- 9,104,987(+) ttttt(C/T)cgaga upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR7G2 Gene

Variant ID Type Subtype PubMed ID
nsv509720 CNV Insertion 20534489

Relevant External Links for OR7G2 Gene

HapMap Linkage Disequilibrium report
OR7G2

Disorders for OR7G2 Gene

No disorders were found for OR7G2 Gene.

No data available for UniProtKB/Swiss-Prot for OR7G2 Gene

Publications for OR7G2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for OR7G2 Gene

Sources for OR7G2 Gene

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