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Aliases for OR7G1 Gene

Aliases for OR7G1 Gene

  • Olfactory Receptor, Family 7, Subfamily G, Member 1 2 3
  • Olfactory Receptor OR19-8 3 4
  • Olfactory Receptor 19-15 3 4
  • OR19-15 3 4
  • OR7G1P 3 4
  • Olfactory Receptor 7G1 3
  • OR19-8 3

External Ids for OR7G1 Gene

Previous HGNC Symbols for OR7G1 Gene

  • OR7G1P

Previous GeneCards Identifiers for OR7G1 Gene

  • GC19U990182
  • GC19M009088
  • GC19M009225

Summaries for OR7G1 Gene

Entrez Gene Summary for OR7G1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7G1 Gene

OR7G1 (Olfactory Receptor, Family 7, Subfamily G, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G2.

UniProtKB/Swiss-Prot for OR7G1 Gene

  • Odorant receptor.

Gene Wiki entry for OR7G1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7G1 Gene

Genomics for OR7G1 Gene

Regulatory Elements for OR7G1 Gene

Genomic Location for OR7G1 Gene

Start:
9,114,828 bp from pter
End:
9,115,763 bp from pter
Size:
936 bases
Orientation:
Minus strand

Genomic View for OR7G1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7G1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7G1 Gene

Proteins for OR7G1 Gene

  • Protein details for OR7G1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGA0-OR7G1_HUMAN
    Recommended name:
    Olfactory receptor 7G1
    Protein Accession:
    Q8NGA0
    Secondary Accessions:
    • Q6IFJ5
    • Q96RA1

    Protein attributes for OR7G1 Gene

    Size:
    311 amino acids
    Molecular mass:
    34803 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC06141.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for OR7G1 Gene

Proteomics data for OR7G1 Gene at MOPED

Post-translational modifications for OR7G1 Gene

Other Protein References for OR7G1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7G1 Gene

Domains for OR7G1 Gene

Gene Families for OR7G1 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7G1 Gene

Suggested Antigen Peptide Sequences for OR7G1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGA0

UniProtKB/Swiss-Prot:

OR7G1_HUMAN :
  • Q8NGA0
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7G1: view

Function for OR7G1 Gene

Molecular function for OR7G1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7G1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR7G1 Gene

Localization for OR7G1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7G1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7G1 Gene COMPARTMENTS Subcellular localization image for OR7G1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7G1: view

Pathways for OR7G1 Gene

genes like me logo Genes that share pathways with OR7G1: view

Pathways by source for OR7G1 Gene

Interacting Proteins for OR7G1 Gene

Gene Ontology (GO) - Biological Process for OR7G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7G1: view

Transcripts for OR7G1 Gene

mRNA/cDNA for OR7G1 Gene

(1) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR7G1 Gene

No ASD Table

Relevant External Links for OR7G1 Gene

GeneLoc Exon Structure for
OR7G1
ECgene alternative splicing isoforms for
OR7G1

Expression for OR7G1 Gene

mRNA expression in normal human tissues for OR7G1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR7G1 Gene

SOURCE GeneReport for Unigene cluster for OR7G1 Gene Hs.553576

genes like me logo Genes that share expressions with OR7G1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR7G1 Gene

Orthologs for OR7G1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7G1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC468707 35
  • 98.29 (n)
  • 96.78 (a)
PTR211 36
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 76 (a)
OneToMany
-- 36
  • 73 (a)
OneToMany
LOC511678 35
  • 83.28 (n)
  • 77.85 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 77 (a)
OneToMany
-- 36
  • 75 (a)
OneToMany
LOC484982 35
  • 83.77 (n)
  • 79.22 (a)
mouse
(Mus musculus)
Mammalia Olfr828 16
Olfr834 36
  • 61 (a)
ManyToMany
Olfr853 36
  • 67 (a)
ManyToMany
Olfr854 35
  • 73.38 (n)
  • 65.91 (a)
rat
(Rattus norvegicus)
Mammalia Olr1149 35
  • 73.01 (n)
  • 66.23 (a)
Species with no ortholog for OR7G1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7G1 Gene

ENSEMBL:
Gene Tree for OR7G1 (if available)
TreeFam:
Gene Tree for OR7G1 (if available)

Paralogs for OR7G1 Gene

Paralogs for OR7G1 Gene

Selected SIMAP similar genes for OR7G1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR7G1 Gene

genes like me logo Genes that share paralogs with OR7G1: view

Variants for OR7G1 Gene

Sequence variations from dbSNP and Humsavar for OR7G1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1036224 -- 9,117,520(-) TGTGA(A/G)GTATG upstream-variant-2KB
rs1036225 -- 9,117,489(-) GGAGA(C/G)ATGCT upstream-variant-2KB
rs2195951 - 9,115,009(-) GTTCT(A/G)TGGGA reference, missense
rs2217657 - 9,115,341(-) TTCTG(C/G/T)GGCTT missense, reference
rs6511874 - 9,115,516(+) TGTTC(A/G)CTAGG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR7G1 Gene

Variant ID Type Subtype PubMed ID
nsv509720 CNV Insertion 20534489

Relevant External Links for OR7G1 Gene

HapMap Linkage Disequilibrium report
OR7G1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7G1 Gene

Disorders for OR7G1 Gene

Relevant External Links for OR7G1

Genetic Association Database (GAD)
OR7G1
genes like me logo Genes that share disorders with OR7G1: view

No data available for UniProtKB/Swiss-Prot for OR7G1 Gene

Publications for OR7G1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for OR7G1 Gene

Sources for OR7G1 Gene

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