OR7E24 Gene
protein-coding GIFtS: 44
GCID: GC19P009361
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olfactory receptor, family 7, subfamily E, member 24(Previous names: olfactory receptor, family 7, subfamily E, member 24 pseudogene...)
(Previous symbol: OR7E24P)
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Aliases
for OR7E24 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Olfactory Receptor, Family 7, Subfamily E, Member 241 2 | | OR7E24Q1 2 | | OR7E24P1 2 3 | | Olfactory Receptor OR19-142 3 | | HSHT21 2 | | Olfactory Receptor, Family 7, Subfamily E, Member 24 Pseudogene1 | | OR19-81 2 | | Olfactory Receptor 7E242 |
Export aliases for OR7E24 gene to outside databasesPrevious GC identifers: GC19P009221 GC19P009210 GC19P009213 GC19P009223 |
Summaries
for OR7E24 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OR7E24:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers theperception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors(GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with manyneurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction ofodorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism is independent of other organisms. (provided by RefSeq, Jul2008)
UniProtKB/Swiss-Prot: O7E24_HUMAN, Q6IFN5Function: Odorant receptor (Potential)
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Genomic Views
for OR7E24 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OR7E24 gene promoter:
TBP LHX3b/Lhx3b AML1a SREBP-1c POU6F1 (c2) SREBP-1b SREBP-1a TFIID LHX3a/Lhx3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for OR7E24
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR7E24 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13.2OR7E24 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P009361: view genomic region
(about GC identifiers)
Start:
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9,361,720 bp from pter |
End:
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9,362,736 bp from pter |
Size:
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1,017 bases |
Orientation:
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plus strand |
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Proteins
for OR7E24 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: O7E24_HUMAN, Q6IFN5 (See
protein sequence)Recommended Name: Olfactory receptor 7E24 Size: 339 amino acids; 38279 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAD03353.1; Type=Erroneous gene model prediction;
Secondary accessions: B9EJD9 Q9UPJ1Explore the universe of human proteins at neXtProt for OR7E24: NX_Q6IFN5
HORDE protein sequence for OR7E24
OR7E24 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073404.1
ENSEMBL proteins: ENSP00000387523 Reactome Protein details: Q6IFN5
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
TAS | -- | | GO:0016021 | integral to membrane |
IEA | -- |
OR7E24 for ontologies About GeneDecksing
OR7E24 Antibody Products:
Assay Products for OR7E24: |
Protein
Domains /
Families
for OR7E24 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OR7E24 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6IFN5ProtoNet protein and cluster: Q6IFN5 1 Blocks protein family: IPB000725 Olfactory receptor signature
UniProtKB/Swiss-Prot: O7E24_HUMAN, Q6IFN5Similarity: Belongs to the G-protein coupled receptor 1 family |
Function
for OR7E24 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: O7E24_HUMAN, Q6IFN5Function: Odorant receptor (Potential) Genatlas biochemistry entry for OR7E24:olfactory receptor,family 7,subfamily E,member 24,G protein coupled receptor superfamily
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector: OR7E24 (NM_001079935) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OR7E24 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR7E24 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004930 | G-protein coupled receptor activity |
IEA | -- | | GO:0004984 | olfactory receptor activity |
IEA | -- |
OR7E24 for ontologies About GeneDecksing
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Pathways & Interactions
for OR7E24 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Signaling by GPCR | | | 2 | Olfactory transduction | | | 3 | GPCRs, Other | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for OR7E24
4 
Reactome Pathways for OR7E24
1 
Kegg Pathway (Kegg details for OR7E24):
OR7E24 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR7E24
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/273 Interacting proteins for OR7E24 (ENSP000003875234) via UniProtKB, MINT, STRING, and/or I2D (see all 273)About this table
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Drugs & Compounds
for OR7E24 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for OR7E24
Search CenterWatch for drugs/clinical trials and news about OR7E24 / O7E24
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Transcripts
for OR7E24 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OR7E24 gene: NM_001079935.1 Unigene Cluster for OR7E24: Olfactory receptor, family 7, subfamily E, member 24 Hs.129832 [show with all ESTs]Unigene Representative Sequence: BC1469201 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000456448(uc002mlb.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: OR7E24 (NM_001079935) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OR7E24 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR7E24 |
Additional cDNA sequence: BC146920.1 Y10529.1 1 DOTS entry: DT.202923 5 AceView cDNA sequences: BX279722 BF062364 BE501015 Y10529 AA758739
GeneLoc Exon Structure
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Expression
for OR7E24 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OR7E24 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAGAATCAT
About this image
See OR7E24 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OR7E24
SOURCE GeneReport for Unigene cluster: Hs.129832
SABiosciences Custom PCR Arrays for OR7E24
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OR7E24
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OR7E24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR7E24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR7E24 |
Orthologs
for OR7E24 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for OR7E24 (if available)
TreeFam Gene Tree for OR7E24 (if available) |
Paralogs
for OR7E24 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for OR7E24 gene
18/455 SIMAP similar genes for OR7E24 using alignment to 1 protein entry: O7E24_HUMAN(see all similar genes):LOC441453 tpcr110 OR7E86P OR7E5P OR7A2P OR7C2
OR7E85P OR7G2 OR7G3 OR7A10 OR7A17 PJCG2
OR7D4 OR7E18P OR7E35P OR7G1 OR7A5 OR7C1
OR7E24 for paralogs About GeneDecksing
5/80 Pseudogenes.org Pseudogenes for OR7E24 (see all 80)
PGOHUM00000258459 PGOHUM00000238360 PGOHUM00000238361 PGOHUM00000242117 PGOHUM00000250354
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Genomic Variants
for OR7E24 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OR7E24 ( 9361720 - 9362736 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for OR7E24: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for OR7E24 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OR7E24 for disorders About GeneDecksing
1  disease for OR7E24: About MalaCardsneuronitis
Export disorders for OR7E24 gene to outside databases
|
Publications
for OR7E24 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OR7E24 gene integrated from 9 sources:
(articles sorted by number of sources associating them with OR7E24) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. (PubMed id 9268701)1, 3 Vanderhaeghen P.... Parmentier M. (1997)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- DEFOG: a practical scheme for deciphering families of genes. (PubMed id 12213199)1 Fuchs T.... Shamir R. (2002)
- Expression of a testis-specific member of the olfactory receptor gene family in human primordial germ cells. (PubMed id 11385110)1 Goto T....Monk M. (2001)
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External Searches for OR7E24 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing OR7E24 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OR7E24 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OR7E24 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OR7E24 | Pharmacogenomics, SNPs, Pathways | | HORDE entry for OR7E24 | The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science |
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About This Section
| Patent Information for OR7E24 gene:
Search GeneIP for patents involving OR7E24
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OR7E24 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for OR7E24 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OR7E24 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OR7E24 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OR7E24 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OR7E24 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OR7E24 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OR7E24 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR7E24 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR7E24 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR7E24 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR7E24 |
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 | | | OR7E24 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for OR7E24 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR7E24 |
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