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Aliases for OR7D2 Gene

Aliases for OR7D2 Gene

  • Olfactory Receptor, Family 7, Subfamily D, Member 2 2 3
  • Olfactory Receptor OR19-10 3 4
  • Olfactory Receptor 19-4 3 4
  • HTPCRH03 3 4
  • OR19-4 3 4
  • Olfactory Receptor 7D2 3
  • OR19-10 3

External Ids for OR7D2 Gene

Summaries for OR7D2 Gene

Entrez Gene Summary for OR7D2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7D2 Gene

OR7D2 (Olfactory Receptor, Family 7, Subfamily D, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7D2 Gene

  • Odorant receptor.

Gene Wiki entry for OR7D2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7D2 Gene

Genomics for OR7D2 Gene

Genomic Location for OR7D2 Gene

Start:
9,185,594 bp from pter
End:
9,188,817 bp from pter
Size:
3,224 bases
Orientation:
Plus strand

Genomic View for OR7D2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7D2 Gene

Regulatory Elements for OR7D2 Gene

Proteins for OR7D2 Gene

  • Protein details for OR7D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96RA2-OR7D2_HUMAN
    Recommended name:
    Olfactory receptor 7D2
    Protein Accession:
    Q96RA2
    Secondary Accessions:
    • Q6IFJ7
    • Q8N133

    Protein attributes for OR7D2 Gene

    Size:
    312 amino acids
    Molecular mass:
    34747 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7D2 Gene

Proteomics data for OR7D2 Gene at MOPED

Post-translational modifications for OR7D2 Gene

Other Protein References for OR7D2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR7D2 Gene

Domains for OR7D2 Gene

Gene Families for OR7D2 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7D2 Gene

UniProtKB/Swiss-Prot:

OR7D2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q96RA2
genes like me logo Genes that share domains with OR7D2: view

Function for OR7D2 Gene

Molecular function for OR7D2 Gene

GENATLAS Biochemistry: olfactory receptor,family 7,subfamily D,member 2,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7D2: view

miRNA for OR7D2 Gene

miRTarBase miRNAs that target OR7D2

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR7D2 Gene

Localization for OR7D2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7D2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7D2 Gene COMPARTMENTS Subcellular localization image for OR7D2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7D2: view

Pathways for OR7D2 Gene

genes like me logo Genes that share pathways with OR7D2: view

Pathways by source for OR7D2 Gene

Interacting Proteins for OR7D2 Gene

Gene Ontology (GO) - Biological Process for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IDA 12175488
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7D2: view

Transcripts for OR7D2 Gene

mRNA/cDNA for OR7D2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7D2 Gene

Olfactory receptor, family 7, subfamily D, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR7D2 Gene

No ASD Table

Relevant External Links for OR7D2 Gene

GeneLoc Exon Structure for
OR7D2
ECgene alternative splicing isoforms for
OR7D2

Expression for OR7D2 Gene

mRNA expression in normal human tissues for OR7D2 Gene

mRNA differential expression in normal tissues according to GTEx for OR7D2 Gene

This gene is overexpressed in Testis (7.7).

SOURCE GeneReport for Unigene cluster for OR7D2 Gene Hs.531755

genes like me logo Genes that share expressions with OR7D2: view

Orthologs for OR7D2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7D2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC468710 36
  • 99.04 (n)
  • 98.4 (a)
OR7D2 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR7D2 36
  • 87.39 (n)
  • 86.86 (a)
OR7D2 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 63 (a)
ManyToMany
LOC611376 36
  • 87.29 (n)
  • 88.78 (a)
mouse
(Mus musculus)
Mammalia Olfr853 16
Olfr871 37
  • 62 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 64 (a)
ManyToMany
-- 37
  • 62 (a)
ManyToMany
-- 37
  • 61 (a)
ManyToMany
-- 37
  • 64 (a)
ManyToMany
-- 37
  • 60 (a)
ManyToMany
-- 37
  • 58 (a)
ManyToMany
-- 37
  • 61 (a)
ManyToMany
-- 37
  • 61 (a)
ManyToMany
-- 37
  • 64 (a)
ManyToMany
OPOR13 37
  • 59 (a)
ManyToMany
OPOR142 37
  • 60 (a)
ManyToMany
OPOR17 37
  • 64 (a)
ManyToMany
OPOR20 37
  • 63 (a)
ManyToMany
OPOR21 37
  • 61 (a)
ManyToMany
OPOR24 37
  • 61 (a)
ManyToMany
OPOR9 37
  • 63 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 58 (a)
ManyToMany
-- 37
  • 55 (a)
ManyToMany
-- 37
  • 54 (a)
ManyToMany
-- 37
  • 55 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr1193 36
  • 68.42 (n)
  • 64.8 (a)
Species with no ortholog for OR7D2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7D2 Gene

ENSEMBL:
Gene Tree for OR7D2 (if available)
TreeFam:
Gene Tree for OR7D2 (if available)

Paralogs for OR7D2 Gene

Paralogs for OR7D2 Gene

Selected SIMAP similar genes for OR7D2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR7D2 Gene

genes like me logo Genes that share paralogs with OR7D2: view

Variants for OR7D2 Gene

Sequence variations from dbSNP and Humsavar for OR7D2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs6511918 -- 9,187,688(+) catat(C/T)ccttt utr-variant-3-prime
rs7246654 -- 9,187,198(+) CGCCC(A/G)GCCAA utr-variant-3-prime
rs7247330 -- 9,187,847(+) agttg(A/C)tacaa utr-variant-3-prime
rs7249045 -- 9,185,605(+) tttga(A/G)acagt utr-variant-5-prime
rs7254803 -- 9,188,900(+) TTTCA(G/T)TAAAC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR7D2 Gene

Variant ID Type Subtype PubMed ID
nsv509720 CNV Insertion 20534489
nsv911020 CNV Gain 21882294
nsv2411 CNV Loss 18451855
nsv911021 CNV Loss 21882294
nsv516657 CNV Gain 19592680
nsv523472 CNV Loss 19592680
nsv911022 CNV Loss 21882294

Relevant External Links for OR7D2 Gene

HapMap Linkage Disequilibrium report
OR7D2

Disorders for OR7D2 Gene

No disorders were found for OR7D2 Gene.

No data available for UniProtKB/Swiss-Prot for OR7D2 Gene

Publications for OR7D2 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 3
  5. A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead. (PMID: 12175488) Wilanowski T. … Jane S.M. (Mech. Dev. 2002) 3

Products for OR7D2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate OR7D2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for OR7D2
    • Block miRNA regulation of OR7D2 using miScript Target Protectors

    Sources for OR7D2 Gene

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