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Aliases for OR7D2 Gene

Aliases for OR7D2 Gene

  • Olfactory Receptor Family 7 Subfamily D Member 2 2 3 5
  • Olfactory Receptor OR19-10 3 4
  • Olfactory Receptor 19-4 3 4
  • HTPCRH03 3 4
  • OR19-4 3 4
  • Olfactory Receptor, Family 7, Subfamily D, Member 2 2
  • Olfactory Receptor 7D2 3
  • OR19-10 3

External Ids for OR7D2 Gene

Previous GeneCards Identifiers for OR7D2 Gene

  • GC19U990187
  • GC19P009298

Summaries for OR7D2 Gene

Entrez Gene Summary for OR7D2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7D2 Gene

OR7D2 (Olfactory Receptor Family 7 Subfamily D Member 2) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7D4.

UniProtKB/Swiss-Prot for OR7D2 Gene

  • Odorant receptor.

Gene Wiki entry for OR7D2 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7D2 Gene

Genomics for OR7D2 Gene

Regulatory Elements for OR7D2 Gene

Enhancers for OR7D2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G009139 1.1 ENCODE 53.7 -44.9 -44906 1.8 PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF766 CBX5 ZNF207 OR7D2 ZNF317 ELOCP29
GH19G009074 1.3 Ensembl ENCODE 8.2 -110.1 -110058 1.7 PKNOX1 ARNT SIN3A ZNF2 ZNF766 FOS JUNB REST SMARCB1 ZNF592 UBE2L4 MUC16 ENSG00000267510 ZNF414 ZNF177 OR7G1 ENSG00000267612 OR7G3 LOC100419831 RPL10P15
GH19G009936 0.7 ENCODE 5.1 +751.4 751356 1.5 BCOR ZSCAN5A ZEB1 ZFHX2 ZNF157 POLR2A PATZ1 EGR2 BHLHE40 ZNF398 ZNF177 LOC100996288 ENSG00000267273 ENSG00000200237 OLFM2 OR7D2 ENSG00000267650
GH19G009057 0.7 ENCODE 4.6 -126.5 -126450 2.5 BCOR PKNOX1 ATF1 ZMYM3 ZNF384 CEBPG ZIC2 CTBP1 POLR3A CREM MUC16 OR7D2 GC19P009058 OR1M4P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR7D2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR7D2 Gene

9,185,594 bp from pter
9,188,817 bp from pter
3,224 bases
Plus strand

Genomic View for OR7D2 Gene

Genes around OR7D2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7D2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7D2 Gene

Proteins for OR7D2 Gene

  • Protein details for OR7D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 7D2
    Protein Accession:
    Secondary Accessions:
    • Q6IFJ7
    • Q8N133

    Protein attributes for OR7D2 Gene

    312 amino acids
    Molecular mass:
    34747 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7D2 Gene

Post-translational modifications for OR7D2 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR7D2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7D2 Gene

Domains & Families for OR7D2 Gene

Gene Families for OR7D2 Gene

Protein Domains for OR7D2 Gene

Suggested Antigen Peptide Sequences for OR7D2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7D2: view

Function for OR7D2 Gene

Molecular function for OR7D2 Gene

GENATLAS Biochemistry:
olfactory receptor,family 7,subfamily D,member 2,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7D2: view

Animal Model Products

CRISPR Products

miRNA for OR7D2 Gene

miRTarBase miRNAs that target OR7D2

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR7D2 Gene

Localization for OR7D2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7D2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR7D2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7D2: view

Pathways & Interactions for OR7D2 Gene

genes like me logo Genes that share pathways with OR7D2: view

Pathways by source for OR7D2 Gene

Interacting Proteins for OR7D2 Gene

Gene Ontology (GO) - Biological Process for OR7D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated IDA 12175488
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
genes like me logo Genes that share ontologies with OR7D2: view

No data available for SIGNOR curated interactions for OR7D2 Gene

Drugs & Compounds for OR7D2 Gene

No Compound Related Data Available

Transcripts for OR7D2 Gene

mRNA/cDNA for OR7D2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7D2 Gene

Olfactory receptor, family 7, subfamily D, member 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7D2 Gene

No ASD Table

Relevant External Links for OR7D2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR7D2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR7D2 Gene

mRNA differential expression in normal tissues according to GTEx for OR7D2 Gene

This gene is overexpressed in Testis (x7.7).

NURSA nuclear receptor signaling pathways regulating expression of OR7D2 Gene:


SOURCE GeneReport for Unigene cluster for OR7D2 Gene:

genes like me logo Genes that share expression patterns with OR7D2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR7D2 Gene

Orthologs for OR7D2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7D2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC468710 34
  • 99.04 (n)
OR7D2 35
  • 98 (a)
(Bos Taurus)
Mammalia OR7D2 34 35
  • 87.39 (n)
(Canis familiaris)
Mammalia LOC611376 34
  • 87.29 (n)
-- 35
  • 63 (a)
(Rattus norvegicus)
Mammalia Olr1193 34
  • 68.42 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 64 (a)
-- 35
  • 64 (a)
-- 35
  • 64 (a)
OPOR17 35
  • 64 (a)
OPOR20 35
  • 63 (a)
OPOR9 35
  • 63 (a)
-- 35
  • 62 (a)
-- 35
  • 61 (a)
-- 35
  • 61 (a)
-- 35
  • 61 (a)
OPOR21 35
  • 61 (a)
OPOR24 35
  • 61 (a)
-- 35
  • 60 (a)
OPOR142 35
  • 60 (a)
OPOR13 35
  • 59 (a)
-- 35
  • 58 (a)
(Mus musculus)
Mammalia Olfr871 35
  • 62 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 58 (a)
-- 35
  • 55 (a)
-- 35
  • 55 (a)
-- 35
  • 54 (a)
Species where no ortholog for OR7D2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7D2 Gene

Gene Tree for OR7D2 (if available)
Gene Tree for OR7D2 (if available)

Paralogs for OR7D2 Gene

Paralogs for OR7D2 Gene

(456) SIMAP similar genes for OR7D2 Gene using alignment to 1 proteins: Pseudogenes for OR7D2 Gene

genes like me logo Genes that share paralogs with OR7D2: view

Variants for OR7D2 Gene

Sequence variations from dbSNP and Humsavar for OR7D2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1001056235 -- 9,188,041(+) GGTAG(A/G)TACCC utr-variant-3-prime
rs1001125083 -- 9,188,035(+) CCTTT(A/G)GGTAG utr-variant-3-prime
rs1001929661 -- 9,187,346(+) ACTAC(A/C)TTACT utr-variant-3-prime
rs1001957551 -- 9,187,608(+) CCCAA(A/G)TGGTA utr-variant-3-prime
rs1002149704 -- 9,183,641(+) TATTA(A/G)CTAAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR7D2 Gene

Variant ID Type Subtype PubMed ID
esv2762024 CNV gain 21179565
nsv2411 CNV deletion 18451855
nsv509720 CNV insertion 20534489
nsv516657 CNV gain 19592680
nsv523472 CNV loss 19592680

Variation tolerance for OR7D2 Gene

Residual Variation Intolerance Score: 74.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.60; 45.08% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR7D2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7D2 Gene

Disorders for OR7D2 Gene

Relevant External Links for OR7D2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR7D2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR7D2 Gene

Publications for OR7D2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64
  4. A highly conserved novel family of mammalian developmental transcription factors related to Drosophila grainyhead. (PMID: 12175488) Wilanowski T. … Jane S.M. (Mech. Dev. 2002) 3 64
  5. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 3 64

Products for OR7D2 Gene

Sources for OR7D2 Gene

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