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Aliases for OR7C2 Gene

Aliases for OR7C2 Gene

  • Olfactory Receptor Family 7 Subfamily C Member 2 2 3 5
  • Olfactory Receptor, Family 7, Subfamily C, Member 2 2 3
  • Olfactory Receptor OR19-22 3 4
  • Olfactory Receptor 19-18 3 4
  • Olfactory Receptor 7C3 3 4
  • OR19-18 3 4
  • OR7C3 3 4
  • Olfactory Receptor, Family 7, Subfamily C, Member 3 3
  • CIT-HSP-87M17 3

External Ids for OR7C2 Gene

Previous HGNC Symbols for OR7C2 Gene

  • OR7C3

Previous GeneCards Identifiers for OR7C2 Gene

  • GC19P015431
  • GC19P014853
  • GC19P014913
  • GC19P014869
  • GC19P015052

Summaries for OR7C2 Gene

Entrez Gene Summary for OR7C2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7C2 Gene

OR7C2 (Olfactory Receptor Family 7 Subfamily C Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7D2.

UniProtKB/Swiss-Prot for OR7C2 Gene

  • Odorant receptor.

Gene Wiki entry for OR7C2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7C2 Gene

Genomics for OR7C2 Gene

Regulatory Elements for OR7C2 Gene

Enhancers for OR7C2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR7C2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR7C2 Gene

14,941,489 bp from pter
14,942,448 bp from pter
960 bases
Plus strand

Genomic View for OR7C2 Gene

Genes around OR7C2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7C2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7C2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7C2 Gene

Proteins for OR7C2 Gene

  • Protein details for OR7C2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 7C2
    Protein Accession:
    Secondary Accessions:
    • O43881
    • Q6IFP9

    Protein attributes for OR7C2 Gene

    319 amino acids
    Molecular mass:
    35323 Da
    Quaternary structure:
    No Data Available
    • Sequence=DAA04611.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR7C2 Gene

Proteomics data for OR7C2 Gene at MOPED

Post-translational modifications for OR7C2 Gene

Other Protein References for OR7C2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Abcam antibodies for OR7C2
  • Santa Cruz Biotechnology (SCBT) Antibodies for OR7C2

No data available for DME Specific Peptides for OR7C2 Gene

Domains & Families for OR7C2 Gene

Gene Families for OR7C2 Gene

Protein Domains for OR7C2 Gene

Suggested Antigen Peptide Sequences for OR7C2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7C2: view

Function for OR7C2 Gene

Molecular function for OR7C2 Gene

GENATLAS Biochemistry:
olfactory receptor,family 7,subfamily C,member 2,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR7C2: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR7C2 Gene

Localization for OR7C2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7C2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR7C2 Gene COMPARTMENTS Subcellular localization image for OR7C2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR7C2: view

Pathways & Interactions for OR7C2 Gene

genes like me logo Genes that share pathways with OR7C2: view

Pathways by source for OR7C2 Gene

1 KEGG pathway for OR7C2 Gene

Interacting Proteins for OR7C2 Gene

Gene Ontology (GO) - Biological Process for OR7C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7C2: view

No data available for SIGNOR curated interactions for OR7C2 Gene

Drugs & Compounds for OR7C2 Gene

No Compound Related Data Available

Transcripts for OR7C2 Gene

mRNA/cDNA for OR7C2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR7C2 Gene

No ASD Table

Relevant External Links for OR7C2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR7C2 Gene

mRNA expression in normal human tissues for OR7C2 Gene

SOURCE GeneReport for Unigene cluster for OR7C2 Gene Hs.589620

genes like me logo Genes that share expression patterns with OR7C2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR7C2 Gene

Orthologs for OR7C2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7C2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR7C2 35
  • 82.65 (n)
  • 75.86 (a)
OR7C2 36
  • 76 (a)
(Mus musculus)
Mammalia Olfr1356 35
  • 78.62 (n)
  • 72.01 (a)
Olfr1356 16
Olfr1356 36
  • 72 (a)
(Pan troglodytes)
Mammalia LOC468751 35
  • 99.16 (n)
  • 98.12 (a)
OR7C2 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Olr1086 35
  • 78.27 (n)
  • 72.78 (a)
(Canis familiaris)
Mammalia OR08B08 36
  • 80 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 65 (a)
-- 36
  • 65 (a)
-- 36
  • 62 (a)
-- 36
  • 65 (a)
-- 36
  • 62 (a)
-- 36
  • 61 (a)
-- 36
  • 61 (a)
-- 36
  • 62 (a)
-- 36
  • 64 (a)
OPOR13 36
  • 60 (a)
OPOR142 36
  • 59 (a)
OPOR17 36
  • 65 (a)
OPOR20 36
  • 66 (a)
OPOR21 36
  • 61 (a)
OPOR24 36
  • 63 (a)
OPOR9 36
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 59 (a)
-- 36
  • 58 (a)
-- 36
  • 56 (a)
-- 36
  • 61 (a)
Species with no ortholog for OR7C2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7C2 Gene

Gene Tree for OR7C2 (if available)
Gene Tree for OR7C2 (if available)

Paralogs for OR7C2 Gene

Paralogs for OR7C2 Gene

(452) SIMAP similar genes for OR7C2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR7C2: view

Variants for OR7C2 Gene

Sequence variations from dbSNP and Humsavar for OR7C2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8113325 - 14,941,841(+) CATGA(C/T)GGCCT reference, missense
rs11883178 - 14,941,853(+) TGACC(A/G)CTTCG reference, missense
rs7256506 -- 14,941,078(+) gaggc(A/G)gaggt upstream-variant-2KB
rs12975813 -- 14,940,559(+) tggct(C/T)atgcc upstream-variant-2KB
rs12976736 -- 14,940,571(+) gtaat(A/G)ccagc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR7C2 Gene

Variant ID Type Subtype PubMed ID
nsv911129 CNV Loss 21882294
nsv510756 CNV Loss 20534489
nsv2424 CNV Loss 18451855

Variation tolerance for OR7C2 Gene

Residual Variation Intolerance Score: 76.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.16; 61.67% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR7C2 Gene

Disorders for OR7C2 Gene

Relevant External Links for OR7C2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR7C2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR7C2 Gene

Publications for OR7C2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Analysis of indel variations in the human disease-associated genes CDKN2AIP, WDR66, USP20 and OR7C2 in a Korean population. (PMID: 22552337) Kim R.N. … Park H.S. (J. Genet. 2012) 3
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3
  4. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR7C2 Gene

Sources for OR7C2 Gene