Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR7A5 Gene

Aliases for OR7A5 Gene

  • Olfactory Receptor, Family 7, Subfamily A, Member 5 2 3
  • Olfactory Receptor, Family 7, Subfamily A, Member 5 Pseudogene 2 3
  • Olfactory Receptor OR19-17 3 4
  • Olfactory Receptor TPCR92 3 4
  • Olfactory Receptor 7A5 3
  • HTPCR2 3

External Ids for OR7A5 Gene

Summaries for OR7A5 Gene

Entrez Gene Summary for OR7A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7A5 Gene

OR7A5 (Olfactory Receptor, Family 7, Subfamily A, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7A5 Gene

  • Odorant receptor.

Gene Wiki entry for OR7A5 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7A5 Gene

Genomics for OR7A5 Gene

Genomic Location for OR7A5 Gene

Start:
14,792,490 bp from pter
End:
14,835,376 bp from pter
Size:
42,887 bases
Orientation:
Minus strand

Genomic View for OR7A5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7A5 Gene

Regulatory Elements for OR7A5 Gene

Proteins for OR7A5 Gene

  • Protein details for OR7A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15622-OR7A5_HUMAN
    Recommended name:
    Olfactory receptor 7A5
    Protein Accession:
    Q15622
    Secondary Accessions:
    • B2R682
    • Q6IFP1
    • Q96R96

    Protein attributes for OR7A5 Gene

    Size:
    319 amino acids
    Molecular mass:
    35579 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7A5 Gene

Proteomics data for OR7A5 Gene at MOPED

Post-translational modifications for OR7A5 Gene

Other Protein References for OR7A5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR7A5 Gene

Domains for OR7A5 Gene

Gene Families for OR7A5 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7A5 Gene

Suggested Antigen Peptide Sequences for OR7A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q15622

UniProtKB/Swiss-Prot:

OR7A5_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q15622
genes like me logo Genes that share domains with OR7A5: view

Function for OR7A5 Gene

Molecular function for OR7A5 Gene

GENATLAS Biochemistry: olfactory receptor,family 7,subfamily A,member 5,pseudogene,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9119360
genes like me logo Genes that share ontologies with OR7A5: view

Phenotypes for OR7A5 Gene

GenomeRNAi human phenotypes for OR7A5:
genes like me logo Genes that share phenotypes with OR7A5: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR7A5 Gene

Localization for OR7A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7A5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7A5 Gene COMPARTMENTS Subcellular localization image for OR7A5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 9119360
genes like me logo Genes that share ontologies with OR7A5: view

Pathways for OR7A5 Gene

genes like me logo Genes that share pathways with OR7A5: view

Pathways by source for OR7A5 Gene

1 KEGG pathway for OR7A5 Gene

Interacting Proteins for OR7A5 Gene

Gene Ontology (GO) - Biological Process for OR7A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell NAS 9119360
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9119360
genes like me logo Genes that share ontologies with OR7A5: view

Transcripts for OR7A5 Gene

mRNA/cDNA for OR7A5 Gene

(4) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7A5 Gene

Olfactory receptor, family 7, subfamily A, member 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR7A5 Gene

No ASD Table

Relevant External Links for OR7A5 Gene

GeneLoc Exon Structure for
OR7A5
ECgene alternative splicing isoforms for
OR7A5

Expression for OR7A5 Gene

mRNA expression in normal human tissues for OR7A5 Gene

mRNA differential expression in normal tissues according to GTEx for OR7A5 Gene

This gene is overexpressed in Brain - Substantia nigra (9.6), Brain - Spinal cord (cervical c-1) (6.4), and Pituitary (4.2).

SOURCE GeneReport for Unigene cluster for OR7A5 Gene Hs.137573

genes like me logo Genes that share expressions with OR7A5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for OR7A5 Gene

Orthologs for OR7A5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7A5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747786 35
  • 99.27 (n)
  • 99.06 (a)
OR7A5 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC783313 35
  • 80.13 (n)
  • 73.72 (a)
dog
(Canis familiaris)
Mammalia LOC610545 35
  • 81.96 (n)
  • 80.2 (a)
mouse
(Mus musculus)
Mammalia Olfr1355 36
  • 65 (a)
ManyToMany
Olfr19 16
Olfr57 35
  • 78.99 (n)
  • 72.28 (a)
rat
(Rattus norvegicus)
Mammalia Olr1075 35
  • 78.23 (n)
  • 72.87 (a)
Species with no ortholog for OR7A5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7A5 Gene

ENSEMBL:
Gene Tree for OR7A5 (if available)
TreeFam:
Gene Tree for OR7A5 (if available)

Paralogs for OR7A5 Gene

Paralogs for OR7A5 Gene

Selected SIMAP similar genes for OR7A5 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR7A5 Gene

genes like me logo Genes that share paralogs with OR7A5: view

Variants for OR7A5 Gene

Relevant External Links for OR7A5 Gene

HapMap Linkage Disequilibrium report
OR7A5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR7A5 Gene

Disorders for OR7A5 Gene

No disorders were found for OR7A5 Gene.

No data available for UniProtKB/Swiss-Prot for OR7A5 Gene

Publications for OR7A5 Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 3 4
  2. Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome. (PMID: 9268701) Vanderhaeghen P. … Parmentier M. (Biochem. Biophys. Res. Commun. 1997) 3 4
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4

Products for OR7A5 Gene

Sources for OR7A5 Gene

Back to Top

Content