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Aliases for OR7A17 Gene

Aliases for OR7A17 Gene

  • Olfactory Receptor Family 7 Subfamily A Member 17 2 3 5
  • Olfactory Receptor, Family 7, Subfamily A, Member 17 2 3
  • Olfactory Receptor OR19-20 3
  • BC85395_4 3
  • HTPCRX19 3

External Ids for OR7A17 Gene

Previous GeneCards Identifiers for OR7A17 Gene

  • GC19M015360
  • GC19M015384
  • GC19M014836
  • GC19M014852
  • GC19M014991

Summaries for OR7A17 Gene

Entrez Gene Summary for OR7A17 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7A17 Gene

OR7A17 (Olfactory Receptor Family 7 Subfamily A Member 17) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7D2.

UniProtKB/Swiss-Prot for OR7A17 Gene

  • Odorant receptor.

Gene Wiki entry for OR7A17 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7A17 Gene

Genomics for OR7A17 Gene

Regulatory Elements for OR7A17 Gene

Genomic Location for OR7A17 Gene

Chromosome:
19
Start:
14,880,426 bp from pter
End:
14,881,452 bp from pter
Size:
1,027 bases
Orientation:
Minus strand

Genomic View for OR7A17 Gene

Genes around OR7A17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR7A17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR7A17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7A17 Gene

Proteins for OR7A17 Gene

  • Protein details for OR7A17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14581-OR7AH_HUMAN
    Recommended name:
    Olfactory receptor 7A17
    Protein Accession:
    O14581
    Secondary Accessions:
    • Q6IFQ6
    • Q96R98

    Protein attributes for OR7A17 Gene

    Size:
    309 amino acids
    Molecular mass:
    34013 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7A17 Gene

Proteomics data for OR7A17 Gene at MOPED

Post-translational modifications for OR7A17 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR7A17 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7A17 Gene

Domains & Families for OR7A17 Gene

Gene Families for OR7A17 Gene

Protein Domains for OR7A17 Gene

Suggested Antigen Peptide Sequences for OR7A17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O14581

UniProtKB/Swiss-Prot:

OR7AH_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7A17: view

Function for OR7A17 Gene

Molecular function for OR7A17 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR7A17: view

Animal Model Products

CRISPR Products

miRNA for OR7A17 Gene

miRTarBase miRNAs that target OR7A17

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR7A17 Gene

Localization for OR7A17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7A17 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7A17 Gene COMPARTMENTS Subcellular localization image for OR7A17 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,IBA --
genes like me logo Genes that share ontologies with OR7A17: view

Pathways & Interactions for OR7A17 Gene

genes like me logo Genes that share pathways with OR7A17: view

Pathways by source for OR7A17 Gene

1 BioSystems pathway for OR7A17 Gene
1 KEGG pathway for OR7A17 Gene

Interacting Proteins for OR7A17 Gene

Gene Ontology (GO) - Biological Process for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7A17: view

No data available for SIGNOR curated interactions for OR7A17 Gene

Drugs & Compounds for OR7A17 Gene

No Compound Related Data Available

Transcripts for OR7A17 Gene

mRNA/cDNA for OR7A17 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7A17 Gene

Olfactory receptor, family 7, subfamily A, member 17:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7A17 Gene

No ASD Table

Relevant External Links for OR7A17 Gene

GeneLoc Exon Structure for
OR7A17
ECgene alternative splicing isoforms for
OR7A17

Expression for OR7A17 Gene

mRNA expression in normal human tissues for OR7A17 Gene

SOURCE GeneReport for Unigene cluster for OR7A17 Gene Hs.247717

genes like me logo Genes that share expression patterns with OR7A17: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR7A17 Gene

Orthologs for OR7A17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7A17 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC782513 35
  • 81.79 (n)
  • 77.48 (a)
mouse
(Mus musculus)
Mammalia Olfr19 35
  • 78.68 (n)
  • 76.3 (a)
Olfr19 16
Olfr1351 36
  • 68 (a)
ManyToMany
Olfr1352 36
  • 74 (a)
ManyToMany
Olfr1353 36
  • 71 (a)
ManyToMany
Olfr1354 36
  • 65 (a)
ManyToMany
Olfr19 36
  • 76 (a)
ManyToMany
Olfr8 36
  • 63 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC747830 35
  • 86.99 (n)
  • 81.64 (a)
-- 36
  • 81 (a)
ManyToMany
Species with no ortholog for OR7A17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7A17 Gene

ENSEMBL:
Gene Tree for OR7A17 (if available)
TreeFam:
Gene Tree for OR7A17 (if available)

Paralogs for OR7A17 Gene

Paralogs for OR7A17 Gene

(453) SIMAP similar genes for OR7A17 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR7A17: view

Variants for OR7A17 Gene

Sequence variations from dbSNP and Humsavar for OR7A17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10405148 - 14,881,246(+) CAGTG(A/G)CCAGG reference, missense
rs10405129 - 14,881,219(+) CCAGG(A/G)TGATG reference, missense
rs10404119 - 14,881,151(+) GTCTG(A/C)AAAGG reference, missense
rs13345394 - 14,880,647(+) AAATG(C/T)CTTGT reference, missense
rs2010422 -- 14,883,269(+) GCCCC(A/G)TCTGT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR7A17 Gene

Variant ID Type Subtype PubMed ID
nsv911129 CNV Loss 21882294
esv2718221 CNV Deletion 23290073
esv2669817 CNV Deletion 23128226
esv2718222 CNV Deletion 23290073

Variation tolerance for OR7A17 Gene

Residual Variation Intolerance Score: 80.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.79; 96.68% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR7A17 Gene

HapMap Linkage Disequilibrium report
OR7A17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7A17 Gene

Disorders for OR7A17 Gene

Relevant External Links for OR7A17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR7A17

No disorders were found for OR7A17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR7A17 Gene

Publications for OR7A17 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR7A17 Gene

Sources for OR7A17 Gene

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