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Aliases for OR7A17 Gene

Aliases for OR7A17 Gene

  • Olfactory Receptor, Family 7, Subfamily A, Member 17 2 3
  • Olfactory Receptor OR19-20 3
  • Olfactory Receptor 7A17 3
  • BC85395_4 3
  • HTPCRX19 3

External Ids for OR7A17 Gene

Previous GeneCards Identifiers for OR7A17 Gene

  • GC19M015360
  • GC19M015384
  • GC19M014836
  • GC19M014852
  • GC19M014991

Summaries for OR7A17 Gene

Entrez Gene Summary for OR7A17 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR7A17 Gene

OR7A17 (Olfactory Receptor, Family 7, Subfamily A, Member 17) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR7G1.

UniProtKB/Swiss-Prot for OR7A17 Gene

  • Odorant receptor.

Gene Wiki entry for OR7A17 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR7A17 Gene

Genomics for OR7A17 Gene

Regulatory Elements for OR7A17 Gene

Genomic Location for OR7A17 Gene

Start:
14,880,426 bp from pter
End:
14,881,452 bp from pter
Size:
1,027 bases
Orientation:
Minus strand

Genomic View for OR7A17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR7A17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR7A17 Gene

Proteins for OR7A17 Gene

  • Protein details for OR7A17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O14581-OR7AH_HUMAN
    Recommended name:
    Olfactory receptor 7A17
    Protein Accession:
    O14581
    Secondary Accessions:
    • Q6IFQ6
    • Q96R98

    Protein attributes for OR7A17 Gene

    Size:
    309 amino acids
    Molecular mass:
    34013 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR7A17 Gene

Proteomics data for OR7A17 Gene at MOPED

Post-translational modifications for OR7A17 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR7A17 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR7A17 Gene

Domains for OR7A17 Gene

Gene Families for OR7A17 Gene

HGNC:
  • OR7 :GPCR / Class A : Olfactory receptors

Protein Domains for OR7A17 Gene

Suggested Antigen Peptide Sequences for OR7A17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O14581

UniProtKB/Swiss-Prot:

OR7AH_HUMAN :
  • O14581
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR7A17: view

Function for OR7A17 Gene

Molecular function for OR7A17 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR7A17: view

Animal Model Products

CRISPR Products

miRNA for OR7A17 Gene

miRTarBase miRNAs that target OR7A17

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR7A17

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR7A17 Gene

Localization for OR7A17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR7A17 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR7A17 Gene COMPARTMENTS Subcellular localization image for OR7A17 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR7A17: view

Pathways for OR7A17 Gene

genes like me logo Genes that share pathways with OR7A17: view

Pathways by source for OR7A17 Gene

1 BioSystems pathway for OR7A17 Gene
1 KEGG pathway for OR7A17 Gene

Interacting Proteins for OR7A17 Gene

Gene Ontology (GO) - Biological Process for OR7A17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IBA --
genes like me logo Genes that share ontologies with OR7A17: view

Transcripts for OR7A17 Gene

mRNA/cDNA for OR7A17 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR7A17 Gene

Olfactory receptor, family 7, subfamily A, member 17:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR7A17

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR7A17

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR7A17 Gene

No ASD Table

Relevant External Links for OR7A17 Gene

GeneLoc Exon Structure for
OR7A17
ECgene alternative splicing isoforms for
OR7A17

Expression for OR7A17 Gene

mRNA expression in normal human tissues for OR7A17 Gene

SOURCE GeneReport for Unigene cluster for OR7A17 Gene Hs.247717

genes like me logo Genes that share expressions with OR7A17: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR7A17 Gene

Orthologs for OR7A17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR7A17 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 81 (a)
ManyToMany
LOC747830 35
  • 86.99 (n)
  • 81.64 (a)
cow
(Bos Taurus)
Mammalia LOC782513 35
  • 81.79 (n)
  • 77.48 (a)
mouse
(Mus musculus)
Mammalia Olfr1351 36
  • 68 (a)
ManyToMany
Olfr1352 36
  • 74 (a)
ManyToMany
Olfr1353 36
  • 71 (a)
ManyToMany
Olfr1354 36
  • 65 (a)
ManyToMany
Olfr19 35
  • 78.68 (n)
  • 76.3 (a)
Olfr19 36
  • 76 (a)
ManyToMany
Olfr57 16
Olfr8 36
  • 63 (a)
ManyToMany
Species with no ortholog for OR7A17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR7A17 Gene

ENSEMBL:
Gene Tree for OR7A17 (if available)
TreeFam:
Gene Tree for OR7A17 (if available)

Paralogs for OR7A17 Gene

Paralogs for OR7A17 Gene

Selected SIMAP similar genes for OR7A17 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR7A17: view

Variants for OR7A17 Gene

Sequence variations from dbSNP and Humsavar for OR7A17 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1013551 -- 14,882,810(+) GCGCA(C/T)GCACA upstream-variant-2KB
rs2010422 -- 14,883,269(+) GCCCC(A/G)TCTGT upstream-variant-2KB
rs3030635 -- 14,880,229(+) aaaaa(-/AA)GATTG downstream-variant-500B
rs3752196 -- 14,880,161(+) CACCT(A/T)GTTTC downstream-variant-500B
rs3752197 -- 14,880,264(+) TAAAG(A/G)AATAC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR7A17 Gene

Variant ID Type Subtype PubMed ID
nsv911129 CNV Loss 21882294
esv2718221 CNV Deletion 23290073
esv2669817 CNV Deletion 23128226
esv2718222 CNV Deletion 23290073

Relevant External Links for OR7A17 Gene

HapMap Linkage Disequilibrium report
OR7A17

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR7A17 Gene

Disorders for OR7A17 Gene

No disorders were found for OR7A17 Gene.

No data available for UniProtKB/Swiss-Prot for OR7A17 Gene

Publications for OR7A17 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4

Products for OR7A17 Gene

Sources for OR7A17 Gene

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