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Aliases for OR6V1 Gene

Aliases for OR6V1 Gene

  • Olfactory Receptor, Family 6, Subfamily V, Member 1 2 3
  • Olfactory Receptor OR7-3 3 4
  • Olfactory Receptor 6V1 3
  • GPR138 3

External Ids for OR6V1 Gene

Summaries for OR6V1 Gene

Entrez Gene Summary for OR6V1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6V1 Gene

OR6V1 (Olfactory Receptor, Family 6, Subfamily V, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR9A4.

UniProtKB/Swiss-Prot for OR6V1 Gene

  • Odorant receptor.

Gene Wiki entry for OR6V1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6V1 Gene

Genomics for OR6V1 Gene

Genomic Location for OR6V1 Gene

Start:
143,052,320 bp from pter
End:
143,053,347 bp from pter
Size:
1,028 bases
Orientation:
Plus strand

Genomic View for OR6V1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6V1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6V1 Gene

Regulatory Elements for OR6V1 Gene

Proteins for OR6V1 Gene

  • Protein details for OR6V1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N148-OR6V1_HUMAN
    Recommended name:
    Olfactory receptor 6V1
    Protein Accession:
    Q8N148
    Secondary Accessions:
    • A4D2I0
    • B9EH48
    • Q6IF70

    Protein attributes for OR6V1 Gene

    Size:
    313 amino acids
    Molecular mass:
    34902 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=DAA04790.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR6V1 Gene

Proteomics data for OR6V1 Gene at MOPED

Post-translational modifications for OR6V1 Gene

Other Protein References for OR6V1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR6V1 Gene

Domains for OR6V1 Gene

Gene Families for OR6V1 Gene

HGNC:
  • OR6 :GPCR / Class A : Olfactory receptors

Protein Domains for OR6V1 Gene

UniProtKB/Swiss-Prot:

OR6V1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8N148
genes like me logo Genes that share domains with OR6V1: view

Function for OR6V1 Gene

Molecular function for OR6V1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR6V1: view

miRNA for OR6V1 Gene

miRTarBase miRNAs that target OR6V1

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for OR6V1 Gene

Localization for OR6V1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6V1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR6V1 Gene COMPARTMENTS Subcellular localization image for OR6V1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR6V1: view

Pathways for OR6V1 Gene

genes like me logo Genes that share pathways with OR6V1: view

Pathways by source for OR6V1 Gene

Interacting Proteins for OR6V1 Gene

Gene Ontology (GO) - Biological Process for OR6V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6V1: view

Transcripts for OR6V1 Gene

mRNA/cDNA for OR6V1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR6V1 Gene

No ASD Table

Relevant External Links for OR6V1 Gene

GeneLoc Exon Structure for
OR6V1
ECgene alternative splicing isoforms for
OR6V1

Expression for OR6V1 Gene

mRNA expression in normal human tissues for OR6V1 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR6V1 Gene

SOURCE GeneReport for Unigene cluster for OR6V1 Gene Hs.554721

genes like me logo Genes that share expressions with OR6V1: view

Orthologs for OR6V1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR6V1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC472558 36
  • 98.94 (n)
  • 98.08 (a)
OR6V1 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 42 (a)
ManyToMany
OR6V1 36
  • 85.9 (n)
  • 84.89 (a)
dog
(Canis familiaris)
Mammalia OR6V1 36
  • 87.5 (n)
  • 87.18 (a)
OR6V1 37
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr461 37
  • 43 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia OR6V1 37
  • 70 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii or101-1 37
  • 38 (a)
OneToMany
Species with no ortholog for OR6V1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR6V1 Gene

ENSEMBL:
Gene Tree for OR6V1 (if available)
TreeFam:
Gene Tree for OR6V1 (if available)

Paralogs for OR6V1 Gene

Paralogs for OR6V1 Gene

Selected SIMAP similar genes for OR6V1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR6V1 Gene

genes like me logo Genes that share paralogs with OR6V1: view

Variants for OR6V1 Gene

Sequence variations from dbSNP and Humsavar for OR6V1 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs1506404 -- 143,053,737(-) TCTTC(C/T)CTTGA downstream-variant-500B
rs4725609 -- 143,053,207(+) CTTAC(C/T)TTCTG reference, synonymous-codon
rs7779316 - 143,053,224(+) GACAG(C/T)TAAAA missense, reference
rs7782579 -- 143,051,066(+) TTTTA(C/T)AGCTG upstream-variant-2KB
rs7791886 - 143,053,146(+) AGTCA(A/G)GAAGG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR6V1 Gene

Variant ID Type Subtype PubMed ID
nsv889274 CNV Loss 21882294

Relevant External Links for OR6V1 Gene

HapMap Linkage Disequilibrium report
OR6V1

Disorders for OR6V1 Gene

No disorders were found for OR6V1 Gene.

No data available for UniProtKB/Swiss-Prot for OR6V1 Gene

Publications for OR6V1 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4
  2. Novel human G-protein-coupled receptors. (PMID: 12732197) Vanti W.B. … O'Dowd B.F. (Biochem. Biophys. Res. Commun. 2003) 2 3
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for OR6V1 Gene

Sources for OR6V1 Gene

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