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Aliases for OR6P1 Gene

Aliases for OR6P1 Gene

  • Olfactory Receptor, Family 6, Subfamily P, Member 1 2 3
  • Olfactory Receptor OR1-12 4

External Ids for OR6P1 Gene

Previous GeneCards Identifiers for OR6P1 Gene

  • GC01U990384
  • GC01M155750
  • GC01M155345
  • GC01M156799

Summaries for OR6P1 Gene

Entrez Gene Summary for OR6P1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6P1 Gene

OR6P1 (Olfactory Receptor, Family 6, Subfamily P, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR11L1.

UniProtKB/Swiss-Prot for OR6P1 Gene

  • Odorant receptor.

Gene Wiki entry for OR6P1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6P1 Gene

Genomics for OR6P1 Gene

Genomic Location for OR6P1 Gene

158,562,651 bp from pter
158,563,604 bp from pter
954 bases
Minus strand

Genomic View for OR6P1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6P1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6P1 Gene

No data available for Regulatory Elements for OR6P1 Gene

Proteins for OR6P1 Gene

  • Protein details for OR6P1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 6P1
    Protein Accession:
    Secondary Accessions:
    • Q6IFR9

    Protein attributes for OR6P1 Gene

    317 amino acids
    Molecular mass:
    35831 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR6P1 Gene

Proteomics data for OR6P1 Gene at MOPED

Post-translational modifications for OR6P1 Gene

  • Glycosylation at Asn 3 and Asn 186

Other Protein References for OR6P1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR6P1 Gene

Domains & Families for OR6P1 Gene

Gene Families for OR6P1 Gene

Protein Domains for OR6P1 Gene

Suggested Antigen Peptide Sequences for OR6P1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR6P1: view

Function for OR6P1 Gene

Molecular function for OR6P1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR6P1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR6P1 Gene

Localization for OR6P1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6P1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR6P1 Gene COMPARTMENTS Subcellular localization image for OR6P1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR6P1: view

Pathways & Interactions for OR6P1 Gene

genes like me logo Genes that share pathways with OR6P1: view

Pathways by source for OR6P1 Gene

Interacting Proteins for OR6P1 Gene

Gene Ontology (GO) - Biological Process for OR6P1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6P1: view

No data available for SIGNOR curated interactions for OR6P1 Gene

Drugs & Compounds for OR6P1 Gene

No Compound Related Data Available

Transcripts for OR6P1 Gene

mRNA/cDNA for OR6P1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR6P1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR6P1 Gene

No ASD Table

Relevant External Links for OR6P1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR6P1 Gene

mRNA expression in normal human tissues for OR6P1 Gene

Protein differential expression in normal tissues from HIPED for OR6P1 Gene

This gene is overexpressed in Serum (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR6P1 Gene

SOURCE GeneReport for Unigene cluster for OR6P1 Gene Hs.723122

genes like me logo Genes that share expression patterns with OR6P1: view

Protein tissue co-expression partners for OR6P1 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR6P1 Gene

Orthologs for OR6P1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR6P1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR6P1 35
  • 86.01 (n)
  • 86.44 (a)
OR6P1 36
  • 86 (a)
(Canis familiaris)
Mammalia OR6P1 35
  • 87.91 (n)
  • 90.22 (a)
OR6P1 36
  • 90 (a)
(Mus musculus)
Mammalia Olfr414 35
  • 86.01 (n)
  • 89.91 (a)
Olfr414 16
Olfr414 36
  • 90 (a)
(Pan troglodytes)
Mammalia LOC469530 35
  • 99.26 (n)
  • 98.74 (a)
OR6P1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Olr1601 35
  • 84.75 (n)
  • 88.33 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
-- 36
  • 82 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488993 35
  • 59.34 (n)
  • 55.68 (a)
Species with no ortholog for OR6P1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR6P1 Gene

Gene Tree for OR6P1 (if available)
Gene Tree for OR6P1 (if available)

Paralogs for OR6P1 Gene

Paralogs for OR6P1 Gene

(452) SIMAP similar genes for OR6P1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR6P1: view

Variants for OR6P1 Gene

Sequence variations from dbSNP and Humsavar for OR6P1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs863343 -- 158,564,595(+) TGCCC(A/G)CAGCC upstream-variant-2KB
rs863344 -- 158,565,041(+) GCATA(A/G)TTTTA upstream-variant-2KB
rs863345 -- 158,565,192(+) ATCTA(C/T)TTTTT upstream-variant-2KB
rs7512117 -- 158,562,274(+) ACTTA(C/T)GAAAT downstream-variant-500B
rs7526514 -- 158,562,615(+) AAGAT(G/T)CTGCT downstream-variant-500B

Variation tolerance for OR6P1 Gene

Gene Damage Index Score: 5.91; 74.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR6P1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR6P1 Gene

Disorders for OR6P1 Gene

Relevant External Links for OR6P1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OR6P1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR6P1 Gene

Publications for OR6P1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  2. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 67
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 67

Products for OR6P1 Gene

Sources for OR6P1 Gene

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