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Aliases for OR6F1 Gene

Aliases for OR6F1 Gene

  • Olfactory Receptor, Family 6, Subfamily F, Member 1 2 3
  • Olfactory Receptor OR1-38 3 4
  • Olfactory Receptor OR1-34 Pseudogene 3
  • Olfactory Receptor 6F1 3
  • OR1-34 3
  • OR1-38 3
  • OST731 3

External Ids for OR6F1 Gene

Previous GeneCards Identifiers for OR6F1 Gene

  • GC01U990393
  • GC01M244773
  • GC01M244201
  • GC01M245941
  • GC01M247876

Summaries for OR6F1 Gene

Entrez Gene Summary for OR6F1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6F1 Gene

OR6F1 (Olfactory Receptor, Family 6, Subfamily F, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR9A4.

UniProtKB/Swiss-Prot for OR6F1 Gene

  • Odorant receptor.

Gene Wiki entry for OR6F1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6F1 Gene

Genomics for OR6F1 Gene

Regulatory Elements for OR6F1 Gene

Genomic Location for OR6F1 Gene

247,711,829 bp from pter
247,712,755 bp from pter
927 bases
Minus strand

Genomic View for OR6F1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6F1 Gene

Proteins for OR6F1 Gene

  • Protein details for OR6F1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 6F1
    Protein Accession:
    Secondary Accessions:
    • B2RNV6
    • Q6IF02
    • Q96R39

    Protein attributes for OR6F1 Gene

    308 amino acids
    Molecular mass:
    33961 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR6F1 Gene

Proteomics data for OR6F1 Gene at MOPED

Post-translational modifications for OR6F1 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR6F1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR6F1 Gene

Domains for OR6F1 Gene

Gene Families for OR6F1 Gene

Protein Domains for OR6F1 Gene

Suggested Antigen Peptide Sequences for OR6F1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR6F1: view

Function for OR6F1 Gene

Molecular function for OR6F1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR6F1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR6F1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR6F1 Gene

Localization for OR6F1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6F1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR6F1 Gene COMPARTMENTS Subcellular localization image for OR6F1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR6F1: view

Pathways for OR6F1 Gene

genes like me logo Genes that share pathways with OR6F1: view

Pathways by source for OR6F1 Gene

Interacting Proteins for OR6F1 Gene

Gene Ontology (GO) - Biological Process for OR6F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6F1: view

Transcripts for OR6F1 Gene

mRNA/cDNA for OR6F1 Gene

(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR6F1 Gene

Olfactory receptor, family 6, subfamily F, member 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR6F1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR6F1 Gene

No ASD Table

Relevant External Links for OR6F1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR6F1 Gene

mRNA expression in normal human tissues for OR6F1 Gene

mRNA differential expression in normal tissues according to GTEx for OR6F1 Gene

This gene is overexpressed in Testis (44.4).

SOURCE GeneReport for Unigene cluster for OR6F1 Gene Hs.591529

genes like me logo Genes that share expressions with OR6F1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR6F1 Gene

Orthologs for OR6F1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR6F1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR6F1 35
  • 86.36 (n)
  • 89.94 (a)
OR6F1 36
  • 87 (a)
(Canis familiaris)
Mammalia LOC482210 35
  • 86.26 (n)
  • 89.61 (a)
OR6F1 36
  • 90 (a)
(Mus musculus)
Mammalia Olfr308 35
  • 79.65 (n)
  • 83.12 (a)
Olfr308 16
Olfr308 36
  • 83 (a)
(Pan troglodytes)
Mammalia LOC469750 35
  • 98.92 (n)
  • 98.05 (a)
OR6F1 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC100909966 35
  • 81.26 (n)
  • 83.99 (a)
(Monodelphis domestica)
Mammalia OR6F1 36
  • 68 (a)
(Anolis carolinensis)
Reptilia OR6F1 36
  • 62 (a)
(Danio rerio)
Actinopterygii or101-1 36
  • 35 (a)
Species with no ortholog for OR6F1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR6F1 Gene

Gene Tree for OR6F1 (if available)
Gene Tree for OR6F1 (if available)

Paralogs for OR6F1 Gene

Paralogs for OR6F1 Gene

(456) SIMAP similar genes for OR6F1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR6F1: view

Variants for OR6F1 Gene

Sequence variations from dbSNP and Humsavar for OR6F1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1416105 -- 247,714,369(-) TATAA(A/G)GGTTA upstream-variant-2KB
rs1416106 -- 247,714,250(-) GGGGC(A/G)GCCAG upstream-variant-2KB
rs2282316 - 247,712,113(-) TCACC(C/T)TTGTC missense, reference
rs2282317 -- 247,711,490(-) TTGTC(C/T)TAGTA downstream-variant-500B
rs6587382 -- 247,712,306(+) CCACA(C/G)ACCCA synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for OR6F1 Gene

Variant ID Type Subtype PubMed ID
esv33129 CNV Gain+Loss 17666407
nsv873440 CNV Gain 21882294
dgv204e1 CNV Complex 17122850
esv34503 CNV Gain 17911159
nsv515858 CNV Gain+Loss 19592680
nsv5310 CNV Loss 18451855
nsv873441 CNV Loss 21882294

Relevant External Links for OR6F1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR6F1 Gene

Disorders for OR6F1 Gene

No disorders were found for OR6F1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR6F1 Gene

Publications for OR6F1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Natural selection on the olfactory receptor gene family in humans and chimpanzees. (PMID: 12908129) Gilad Y. … Paabo S. (Am. J. Hum. Genet. 2003) 3

Products for OR6F1 Gene

Sources for OR6F1 Gene

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