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Aliases for OR6C76 Gene

Aliases for OR6C76 Gene

  • Olfactory Receptor, Family 6, Subfamily C, Member 76 2 3

External Ids for OR6C76 Gene

Previous GeneCards Identifiers for OR6C76 Gene

  • GC12P054107
  • GC12P053964
  • GC12P055820

Summaries for OR6C76 Gene

Entrez Gene Summary for OR6C76 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6C76 Gene

OR6C76 (Olfactory Receptor, Family 6, Subfamily C, Member 76) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6C3.

UniProtKB/Swiss-Prot for OR6C76 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6C76 Gene

Genomics for OR6C76 Gene

Regulatory Elements for OR6C76 Gene

Genomic Location for OR6C76 Gene

Start:
55,426,254 bp from pter
End:
55,427,192 bp from pter
Size:
939 bases
Orientation:
Plus strand

Genomic View for OR6C76 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6C76 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6C76 Gene

Proteins for OR6C76 Gene

  • Protein details for OR6C76 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NM76-O6C76_HUMAN
    Recommended name:
    Olfactory receptor 6C76
    Protein Accession:
    A6NM76
    Secondary Accessions:

    Protein attributes for OR6C76 Gene

    Size:
    312 amino acids
    Molecular mass:
    35119 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR6C76 Gene

Proteomics data for OR6C76 Gene at MOPED

Post-translational modifications for OR6C76 Gene

  • Glycosylation at Asn3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR6C76 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR6C76 Gene

Domains for OR6C76 Gene

Gene Families for OR6C76 Gene

HGNC:
  • OR6 :GPCR / Class A : Olfactory receptors

Protein Domains for OR6C76 Gene

Suggested Antigen Peptide Sequences for OR6C76 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NM76

UniProtKB/Swiss-Prot:

O6C76_HUMAN :
  • A6NM76
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR6C76: view

Function for OR6C76 Gene

Molecular function for OR6C76 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6C76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR6C76: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR6C76 Gene

Localization for OR6C76 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6C76 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR6C76 Gene COMPARTMENTS Subcellular localization image for OR6C76 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6C76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR6C76: view

Pathways for OR6C76 Gene

genes like me logo Genes that share pathways with OR6C76: view

Pathways by source for OR6C76 Gene

Interacting Proteins for OR6C76 Gene

Gene Ontology (GO) - Biological Process for OR6C76 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6C76: view

Transcripts for OR6C76 Gene

mRNA/cDNA for OR6C76 Gene

(1) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR6C76 Gene

No ASD Table

Relevant External Links for OR6C76 Gene

GeneLoc Exon Structure for
OR6C76
ECgene alternative splicing isoforms for
OR6C76

Expression for OR6C76 Gene

mRNA expression in normal human tissues for OR6C76 Gene

SOURCE GeneReport for Unigene cluster for OR6C76 Gene Hs.553764

genes like me logo Genes that share expressions with OR6C76: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR6C76 Gene

Orthologs for OR6C76 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR6C76 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR6C76 35
  • 86.47 (n)
  • 88.31 (a)
OR6C76 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR6C76 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr792 35
  • 74.34 (n)
  • 79.28 (a)
Olfr809 16
Olfr809 36
  • 83 (a)
OneToMany
Olfr813 36
  • 86 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 77 (a)
ManyToMany
-- 36
  • 77 (a)
ManyToMany
-- 36
  • 78 (a)
ManyToMany
-- 36
  • 76 (a)
ManyToMany
-- 36
  • 74 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 63 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 67 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
Species with no ortholog for OR6C76:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR6C76 Gene

ENSEMBL:
Gene Tree for OR6C76 (if available)
TreeFam:
Gene Tree for OR6C76 (if available)

Paralogs for OR6C76 Gene

Paralogs for OR6C76 Gene

Selected SIMAP similar genes for OR6C76 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR6C76: view

Variants for OR6C76 Gene

Sequence variations from dbSNP and Humsavar for OR6C76 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs6581046 -- 55,426,337(+) TCGTT(C/T)CTATT reference, synonymous-codon
rs7487750 -- 55,424,724(+) TATGT(A/G)AAGGA upstream-variant-2KB
rs7487767 -- 55,424,712(+) TATTT(C/T)TGAAA upstream-variant-2KB
rs10876774 -- 55,426,149(+) GTATT(C/T)GAAAA upstream-variant-2KB
rs12322458 -- 55,426,574(+) TCAAC(A/G)GAGTT synonymous-codon, reference

Relevant External Links for OR6C76 Gene

HapMap Linkage Disequilibrium report
OR6C76

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR6C76 Gene

Disorders for OR6C76 Gene

No disorders were found for OR6C76 Gene.

No data available for UniProtKB/Swiss-Prot for OR6C76 Gene

Publications for OR6C76 Gene

  1. Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia. (PMID: 24152035) Goodbourn P.T. … Mollon J.D. (Genes Brain Behav. 2014) 3
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4

Products for OR6C76 Gene

Sources for OR6C76 Gene

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