Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR6B3 Gene

Aliases for OR6B3 Gene

  • Olfactory Receptor, Family 6, Subfamily B, Member 3 2 3
  • Olfactory Receptor, Family 6, Subfamily B, Member 3 Pseudogene 2 3
  • Olfactory Receptor OR2-2 3 4
  • OR6B3P 3 4
  • Olfactory Receptor 6B3 3
  • OR6B3Q 3

External Ids for OR6B3 Gene

Previous HGNC Symbols for OR6B3 Gene

  • OR6B3P

Previous GeneCards Identifiers for OR6B3 Gene

  • GC02U900017
  • GC02M241306
  • GC02M240689
  • GC02M240633
  • GC02M240984

Summaries for OR6B3 Gene

Entrez Gene Summary for OR6B3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR6B3 Gene

OR6B3 (Olfactory Receptor, Family 6, Subfamily B, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR11L1.

UniProtKB/Swiss-Prot for OR6B3 Gene

  • Odorant receptor.

Gene Wiki entry for OR6B3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR6B3 Gene

Genomics for OR6B3 Gene

Regulatory Elements for OR6B3 Gene

Genomic Location for OR6B3 Gene

240,045,077 bp from pter
240,046,072 bp from pter
996 bases
Minus strand

Genomic View for OR6B3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR6B3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR6B3 Gene

Proteins for OR6B3 Gene

  • Protein details for OR6B3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 6B3
    Protein Accession:
    Secondary Accessions:
    • Q6IFH3

    Protein attributes for OR6B3 Gene

    331 amino acids
    Molecular mass:
    37232 Da
    Quaternary structure:
    No Data Available
    • Sequence=DAA04687.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR6B3 Gene

Proteomics data for OR6B3 Gene at MOPED

Post-translational modifications for OR6B3 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR6B3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR6B3 Gene

Domains for OR6B3 Gene

Gene Families for OR6B3 Gene

  • OR6 :GPCR / Class A : Olfactory receptors

Protein Domains for OR6B3 Gene

Suggested Antigen Peptide Sequences for OR6B3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8NGW1
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR6B3: view

Function for OR6B3 Gene

Molecular function for OR6B3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR6B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR6B3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR6B3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR6B3 Gene

Localization for OR6B3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR6B3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR6B3 Gene COMPARTMENTS Subcellular localization image for OR6B3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR6B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR6B3: view

Pathways for OR6B3 Gene

genes like me logo Genes that share pathways with OR6B3: view

Pathways by source for OR6B3 Gene

Interacting Proteins for OR6B3 Gene

Gene Ontology (GO) - Biological Process for OR6B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR6B3: view

Transcripts for OR6B3 Gene

mRNA/cDNA for OR6B3 Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR6B3

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR6B3 Gene

No ASD Table

Relevant External Links for OR6B3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR6B3 Gene

mRNA expression in normal human tissues for OR6B3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OR6B3 Gene

This gene is overexpressed in Nerve - Tibial (40.7).

SOURCE GeneReport for Unigene cluster for OR6B3 Gene Hs.626616

genes like me logo Genes that share expressions with OR6B3: view

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR6B3 Gene

Orthologs for OR6B3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR6B3 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Olfr1414 35
  • 86.86 (n)
  • 87.95 (a)
Olfr1414 36
  • 87 (a)
Olfr1415 36
  • 84 (a)
Olfr1416 36
  • 84 (a)
(Rattus norvegicus)
Mammalia Olr1345 35
  • 87.38 (n)
  • 87.38 (a)
(Bos Taurus)
Mammalia -- 36
  • 85 (a)
-- 36
  • 82 (a)
(Canis familiaris)
Mammalia -- 36
  • 81 (a)
-- 36
  • 81 (a)
-- 36
  • 80 (a)
-- 36
  • 80 (a)
OR12C12 36
  • 79 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 75 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 62 (a)
Species with no ortholog for OR6B3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR6B3 Gene

Gene Tree for OR6B3 (if available)
Gene Tree for OR6B3 (if available)

Paralogs for OR6B3 Gene

Paralogs for OR6B3 Gene

Selected SIMAP similar genes for OR6B3 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR6B3: view

Variants for OR6B3 Gene

Sequence variations from dbSNP and Humsavar for OR6B3 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs4854049 -- 240,047,101(-) CAACC(A/C)ACAAC upstream-variant-2KB
rs4854050 -- 240,047,097(-) CAACA(A/G)CTGAA upstream-variant-2KB
rs4854051 -- 240,046,436(-) GACAC(C/T)GGACA upstream-variant-2KB
rs7585039 -- 240,047,697(+) GTTAT(A/G)CACTG upstream-variant-2KB
rs7585425 -- 240,047,969(+) AAACC(A/G)AAAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR6B3 Gene

Variant ID Type Subtype PubMed ID
nsv876099 CNV Gain 21882294
nsv483047 CNV Loss 15286789
nsv525278 CNV Gain 19592680
nsv876112 CNV Loss 21882294
nsv876113 CNV Loss 21882294
nsv3236 CNV Insertion 18451855

Relevant External Links for OR6B3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR6B3 Gene

Disorders for OR6B3 Gene

No disorders were found for OR6B3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR6B3 Gene

Publications for OR6B3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3

Products for OR6B3 Gene

Sources for OR6B3 Gene

Back to Top