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Aliases for OR5W2 Gene

Aliases for OR5W2 Gene

  • Olfactory Receptor, Family 5, Subfamily W, Member 2 2 3
  • Olfactory Receptor OR11-155 3 4
  • Olfactory Receptor 5W3 3 4
  • OR5W2P 3 4
  • OR5W3P 3 4
  • Olfactory Receptor, Family 5, Subfamily W, Member 3 Pseudogene 3
  • Olfactory Receptor 5W2 3

External Ids for OR5W2 Gene

Previous Symbols for OR5W2 Gene

  • OR5W2P
  • OR5W3P

Summaries for OR5W2 Gene

Entrez Gene Summary for OR5W2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5W2 Gene

OR5W2 (Olfactory Receptor, Family 5, Subfamily W, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5I1.

UniProtKB/Swiss-Prot for OR5W2 Gene

  • Odorant receptor.

Gene Wiki entry for OR5W2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5W2 Gene

Genomics for OR5W2 Gene

Genomic Location for OR5W2 Gene

55,913,650 bp from pter
55,914,582 bp from pter
933 bases
Minus strand

Genomic View for OR5W2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5W2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5W2 Gene

Regulatory Elements for OR5W2 Gene

Proteins for OR5W2 Gene

  • Protein details for OR5W2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5W2
    Protein Accession:
    Secondary Accessions:

    Protein attributes for OR5W2 Gene

    310 amino acids
    Molecular mass:
    35167 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5W2 Gene

Proteomics data for OR5W2 Gene at MOPED

Post-translational modifications for OR5W2 Gene

Other Protein References for OR5W2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR5W2 Gene

Domains for OR5W2 Gene

Gene Families for OR5W2 Gene

  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5W2 Gene


  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NH69
genes like me logo Genes that share domains with OR5W2: view

Function for OR5W2 Gene

Molecular function for OR5W2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5W2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5W2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5W2 Gene

Localization for OR5W2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5W2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5W2 Gene COMPARTMENTS Subcellular localization image for OR5W2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5W2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5W2: view

Pathways for OR5W2 Gene

genes like me logo Genes that share pathways with OR5W2: view

Pathways by source for OR5W2 Gene

Interacting Proteins for OR5W2 Gene

Gene Ontology (GO) - Biological Process for OR5W2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5W2: view

Transcripts for OR5W2 Gene

mRNA/cDNA for OR5W2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5W2 Gene

No ASD Table

Relevant External Links for OR5W2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5W2 Gene

mRNA expression in normal human tissues for OR5W2 Gene

SOURCE GeneReport for Unigene cluster for OR5W2 Gene Hs.554526

genes like me logo Genes that share expressions with OR5W2: view

Orthologs for OR5W2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5W2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC747267 36
  • 98.71 (n)
  • 98.39 (a)
OR5W2 37
  • 98 (a)
(Bos Taurus)
Mammalia -- 37
  • 67 (a)
-- 37
  • 67 (a)
-- 37
  • 80 (a)
-- 37
  • 82 (a)
-- 37
  • 83 (a)
-- 37
  • 77 (a)
-- 37
  • 74 (a)
-- 37
  • 65 (a)
-- 37
  • 73 (a)
-- 37
  • 71 (a)
-- 37
  • 72 (a)
-- 37
  • 77 (a)
LOC789300 36
  • 82.25 (n)
  • 82.79 (a)
(Canis familiaris)
Mammalia LOC100685567 36
  • 83.87 (n)
  • 83.87 (a)
OR5W2 37
  • 83 (a)
(Mus musculus)
Mammalia Olfr1131 37
  • 78 (a)
Olfr1132 37
  • 79 (a)
Olfr1135 37
  • 76 (a)
Olfr1136 37
  • 71 (a)
Olfr1137 37
  • 73 (a)
Olfr1138 37
  • 78 (a)
Olfr1140 37
  • 72 (a)
Olfr1141 37
  • 67 (a)
Olfr1143 37
  • 75 (a)
Olfr1151 36
  • 77.71 (n)
  • 79.87 (a)
Olfr1151 16
Olfr1151 37
  • 80 (a)
Olfr1152 37
  • 76 (a)
Olfr1153 37
  • 73 (a)
Olfr153 37
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 37
  • 72 (a)
-- 37
  • 72 (a)
-- 37
  • 72 (a)
(Rattus norvegicus)
Mammalia Olr596 36
  • 77.81 (n)
  • 79.87 (a)
Species with no ortholog for OR5W2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5W2 Gene

Gene Tree for OR5W2 (if available)
Gene Tree for OR5W2 (if available)

Paralogs for OR5W2 Gene

Paralogs for OR5W2 Gene

Selected SIMAP similar genes for OR5W2 Gene using alignment to 1 proteins: Pseudogenes for OR5W2 Gene

genes like me logo Genes that share paralogs with OR5W2: view

Variants for OR5W2 Gene

Sequence variations from dbSNP and Humsavar for OR5W2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2457237 -- 55,916,282(-) TTATC(A/T)TATTT upstream-variant-2KB
rs2457238 -- 55,915,453(-) AACAA(G/T)CAGAC upstream-variant-2KB
rs2457239 - 55,914,018(-) TCTCT(C/T)GCTCA reference, missense
rs2457240 -- 55,913,664(-) AAAAT(A/G)AAATT reference, missense
rs2512730 -- 55,916,509(-) ATCAC(A/G)TTTAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5W2 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
nsv832158 CNV Gain 17160897
nsv437718 CNV Loss 16327808

Relevant External Links for OR5W2 Gene

HapMap Linkage Disequilibrium report

Disorders for OR5W2 Gene

Relevant External Links for OR5W2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with OR5W2: view

No data available for UniProtKB/Swiss-Prot for OR5W2 Gene

Publications for OR5W2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  3. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR5W2 Gene

Sources for OR5W2 Gene

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