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Aliases for OR5V1 Gene

Aliases for OR5V1 Gene

  • Olfactory Receptor Family 5 Subfamily V Member 1 2 3 5
  • Olfactory Receptor OR6-26 3 4
  • Hs6M1-21 3 4
  • Olfactory Receptor, Family 5, Subfamily V, Member 1 2
  • Olfactory Receptor 5V1 3
  • 6M1-21 3

External Ids for OR5V1 Gene

Previous GeneCards Identifiers for OR5V1 Gene

  • GC06M029380
  • GC06M029431
  • GC06M029430
  • GC06M029345
  • GC06Mo29253

Summaries for OR5V1 Gene

Entrez Gene Summary for OR5V1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5V1 Gene

OR5V1 (Olfactory Receptor Family 5 Subfamily V Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR5V1 Gene

  • Odorant receptor.

Gene Wiki entry for OR5V1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5V1 Gene

Genomics for OR5V1 Gene

Regulatory Elements for OR5V1 Gene

Enhancers for OR5V1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around OR5V1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5V1 Gene

29,355,230 bp from pter
29,457,067 bp from pter
101,838 bases
Minus strand

Genomic View for OR5V1 Gene

Genes around OR5V1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5V1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5V1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for OR5V1 Gene

  • Protein details for OR5V1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5V1
    Protein Accession:
    Secondary Accessions:
    • A2BDZ0
    • B0S860
    • Q5SQI9
    • Q6NTB5
    • Q8IVL3

    Protein attributes for OR5V1 Gene

    321 amino acids
    Molecular mass:
    36057 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5V1 Gene

Post-translational modifications for OR5V1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5V1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5V1 Gene

Domains & Families for OR5V1 Gene

Gene Families for OR5V1 Gene

Protein Domains for OR5V1 Gene

Suggested Antigen Peptide Sequences for OR5V1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5V1: view

Function for OR5V1 Gene

Molecular function for OR5V1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
genes like me logo Genes that share ontologies with OR5V1: view
genes like me logo Genes that share phenotypes with OR5V1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5V1 Gene

Localization for OR5V1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5V1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5V1 Gene COMPARTMENTS Subcellular localization image for OR5V1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for OR5V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with OR5V1: view

Pathways & Interactions for OR5V1 Gene

genes like me logo Genes that share pathways with OR5V1: view

Pathways by source for OR5V1 Gene

1 KEGG pathway for OR5V1 Gene

Interacting Proteins for OR5V1 Gene

Gene Ontology (GO) - Biological Process for OR5V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5V1: view

No data available for SIGNOR curated interactions for OR5V1 Gene

Drugs & Compounds for OR5V1 Gene

No Compound Related Data Available

Transcripts for OR5V1 Gene

mRNA/cDNA for OR5V1 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR5V1 Gene

Olfactory receptor, family 5, subfamily V, member 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5V1 Gene

No ASD Table

Relevant External Links for OR5V1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5V1 Gene

mRNA expression in normal human tissues for OR5V1 Gene

mRNA differential expression in normal tissues according to GTEx for OR5V1 Gene

This gene is overexpressed in Testis (x42.4).

NURSA nuclear receptor signaling pathways regulating expression of OR5V1 Gene:


SOURCE GeneReport for Unigene cluster for OR5V1 Gene:

genes like me logo Genes that share expression patterns with OR5V1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR5V1 Gene

Orthologs for OR5V1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR5V1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR5V1 34
  • 85.76 (n)
  • 86.08 (a)
-- 35
  • 75 (a)
-- 35
  • 81 (a)
-- 35
  • 82 (a)
(Mus musculus)
Mammalia Olfr111 34
  • 81.33 (n)
  • 82.59 (a)
Olfr111 16
Olfr110 35
  • 82 (a)
Olfr111 35
  • 82 (a)
(Pan troglodytes)
Mammalia LOC471937 34
  • 98.86 (n)
  • 97.51 (a)
OR5V1 35
  • 98 (a)
(Rattus norvegicus)
Mammalia Olr1730 34
  • 81.86 (n)
  • 81.33 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia OR5V1 35
  • 67 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 69 (a)
-- 35
  • 54 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100491436 34
  • 57.73 (n)
  • 58.76 (a)
Species where no ortholog for OR5V1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5V1 Gene

Gene Tree for OR5V1 (if available)
Gene Tree for OR5V1 (if available)

Paralogs for OR5V1 Gene

(449) SIMAP similar genes for OR5V1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5V1: view

No data available for Paralogs for OR5V1 Gene

Variants for OR5V1 Gene

Sequence variations from dbSNP and Humsavar for OR5V1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs6930033 - 29,356,128(+) ACTGC(A/C)ATTCA reference, missense
rs9257770 - 29,356,061(+) AAGAT(A/C)ATTAA reference, missense
VAR_064740 -
rs994321 -- 29,404,579(-) AAGAA(C/T)TCAAT intron-variant
rs4711184 -- 29,364,521(+) gggcc(A/G)ggcgc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR5V1 Gene

Variant ID Type Subtype PubMed ID
dgv10338n54 CNV gain 21841781
esv3608473 CNV gain 21293372
esv3608477 CNV loss 21293372
nsv1015796 CNV gain 25217958
nsv1020683 CNV gain 25217958
nsv1074389 CNV deletion 25765185
nsv1122126 CNV deletion 24896259
nsv1145096 CNV deletion 24896259
nsv520169 CNV gain 19592680
nsv601223 CNV loss 21841781
nsv830624 CNV loss 17160897

Variation tolerance for OR5V1 Gene

Residual Variation Intolerance Score: 68.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.87; 91.82% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR5V1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5V1 Gene

Disorders for OR5V1 Gene

Relevant External Links for OR5V1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR5V1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5V1 Gene

Publications for OR5V1 Gene

  1. Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors. (PMID: 19833159) Thompson E.E. … Ober C. (Hum. Immunol. 2010) 3 46 65
  2. Host determinants of HIV-1 control in African Americans. (PMID: 20205591) Pelak K. … . (J. Infect. Dis. 2010) 3 46 65
  3. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PMID: 19851445) Barcellos L.F. … Criswell L.A. (PLoS Genet. 2009) 3 46 65
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 65
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 65

Products for OR5V1 Gene

Sources for OR5V1 Gene

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