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Aliases for OR5T3 Gene

Aliases for OR5T3 Gene

  • Olfactory Receptor, Family 5, Subfamily T, Member 3 2 3
  • Olfactory Receptor OR11-178 3 4
  • Olfactory Receptor 5T3 3
  • OR11-178 3
  • OR5T3Q 3

External Ids for OR5T3 Gene

Summaries for OR5T3 Gene

Entrez Gene Summary for OR5T3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5T3 Gene

OR5T3 (Olfactory Receptor, Family 5, Subfamily T, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and serotonin receptor activity. An important paralog of this gene is OR5I1.

UniProtKB/Swiss-Prot for OR5T3 Gene

  • Odorant receptor.

Gene Wiki entry for OR5T3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5T3 Gene

Genomics for OR5T3 Gene

Genomic Location for OR5T3 Gene

Start:
56,252,200 bp from pter
End:
56,253,222 bp from pter
Size:
1,023 bases
Orientation:
Plus strand

Genomic View for OR5T3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5T3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5T3 Gene

Regulatory Elements for OR5T3 Gene

Proteins for OR5T3 Gene

  • Protein details for OR5T3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGG3-OR5T3_HUMAN
    Recommended name:
    Olfactory receptor 5T3
    Protein Accession:
    Q8NGG3
    Secondary Accessions:
    • Q6IFC7

    Protein attributes for OR5T3 Gene

    Size:
    340 amino acids
    Molecular mass:
    38346 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5T3 Gene

Proteomics data for OR5T3 Gene at MOPED

Post-translational modifications for OR5T3 Gene

  • Glycosylation at Asn35 and Asn119

Other Protein References for OR5T3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR5T3 Gene

Domains for OR5T3 Gene

Gene Families for OR5T3 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5T3 Gene

UniProtKB/Swiss-Prot:

OR5T3_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGG3
genes like me logo Genes that share domains with OR5T3: view

Function for OR5T3 Gene

Molecular function for OR5T3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5T3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR5T3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5T3 Gene

Localization for OR5T3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5T3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5T3 Gene COMPARTMENTS Subcellular localization image for OR5T3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5T3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5T3: view

Pathways for OR5T3 Gene

genes like me logo Genes that share pathways with OR5T3: view

Pathways by source for OR5T3 Gene

Interacting Proteins for OR5T3 Gene

Gene Ontology (GO) - Biological Process for OR5T3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5T3: view

Transcripts for OR5T3 Gene

mRNA/cDNA for OR5T3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5T3 Gene

No ASD Table

Relevant External Links for OR5T3 Gene

GeneLoc Exon Structure for
OR5T3
ECgene alternative splicing isoforms for
OR5T3

Expression for OR5T3 Gene

mRNA expression in normal human tissues for OR5T3 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR5T3 Gene

SOURCE GeneReport for Unigene cluster for OR5T3 Gene Hs.553746

genes like me logo Genes that share expressions with OR5T3: view

Orthologs for OR5T3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR5T3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC740517 36
  • 98.45 (n)
  • 96.58 (a)
OR93Ch 37
  • 52 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 37
  • 74 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 81 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr1093 36
  • 81.45 (n)
  • 78.62 (a)
Olfr1093 16
Olfr1093 37
  • 78 (a)
ManyToMany
Olfr1094 37
  • 75 (a)
ManyToMany
Olfr1102 37
  • 73 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 70 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 66 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr519 36
  • 79.14 (n)
  • 77.04 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 54 (a)
OneToMany
Species with no ortholog for OR5T3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5T3 Gene

ENSEMBL:
Gene Tree for OR5T3 (if available)
TreeFam:
Gene Tree for OR5T3 (if available)

Paralogs for OR5T3 Gene

Paralogs for OR5T3 Gene

Selected SIMAP similar genes for OR5T3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5T3: view

Variants for OR5T3 Gene

Sequence variations from dbSNP and Humsavar for OR5T3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs7939774 -- 56,251,985(+) AAAAA(A/T)TTCAA upstream-variant-2KB
rs10791897 -- 56,250,398(+) AGAGA(A/G)AGGAG upstream-variant-2KB
rs10896143 -- 56,250,432(+) AGGAA(C/T)TTGTA upstream-variant-2KB
rs11227638 -- 56,252,109(+) AATTC(A/T)TCTAT upstream-variant-2KB
rs11227640 -- 56,252,194(+) GATAC(A/T)ATTGA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5T3 Gene

Variant ID Type Subtype PubMed ID
nsv521440 CNV Loss 19592680

Relevant External Links for OR5T3 Gene

HapMap Linkage Disequilibrium report
OR5T3

Disorders for OR5T3 Gene

No disorders were found for OR5T3 Gene.

No data available for UniProtKB/Swiss-Prot for OR5T3 Gene

Publications for OR5T3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR5T3 Gene

Sources for OR5T3 Gene

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