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Aliases for OR5T2 Gene

Aliases for OR5T2 Gene

  • Olfactory Receptor, Family 5, Subfamily T, Member 2 2 3
  • Olfactory Receptor OR11-177 3 4
  • Olfactory Receptor 5T2 3
  • OR11-177 3

External Ids for OR5T2 Gene

Previous GeneCards Identifiers for OR5T2 Gene

  • GC11U990418
  • GC11M055775
  • GC11M055756
  • GC11M055999

Summaries for OR5T2 Gene

Entrez Gene Summary for OR5T2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5T2 Gene

OR5T2 (Olfactory Receptor, Family 5, Subfamily T, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and serotonin receptor activity. An important paralog of this gene is OR5I1.

UniProtKB/Swiss-Prot for OR5T2 Gene

  • Odorant receptor.

Gene Wiki entry for OR5T2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5T2 Gene

Genomics for OR5T2 Gene

Regulatory Elements for OR5T2 Gene

Genomic Location for OR5T2 Gene

56,232,106 bp from pter
56,233,185 bp from pter
1,080 bases
Minus strand

Genomic View for OR5T2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5T2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5T2 Gene

Proteins for OR5T2 Gene

  • Protein details for OR5T2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5T2
    Protein Accession:
    Secondary Accessions:
    • B9EGX5
    • Q6IFC8

    Protein attributes for OR5T2 Gene

    359 amino acids
    Molecular mass:
    40696 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5T2 Gene

Proteomics data for OR5T2 Gene at MOPED

Post-translational modifications for OR5T2 Gene

  • Glycosylation at Asn44
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5T2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5T2 Gene

Domains for OR5T2 Gene

Gene Families for OR5T2 Gene

Protein Domains for OR5T2 Gene

Suggested Antigen Peptide Sequences for OR5T2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5T2: view

Function for OR5T2 Gene

Molecular function for OR5T2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5T2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR5T2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5T2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5T2 Gene

Localization for OR5T2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5T2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5T2 Gene COMPARTMENTS Subcellular localization image for OR5T2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5T2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5T2: view

Pathways for OR5T2 Gene

genes like me logo Genes that share pathways with OR5T2: view

Pathways by source for OR5T2 Gene

Interacting Proteins for OR5T2 Gene

Gene Ontology (GO) - Biological Process for OR5T2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5T2: view

Transcripts for OR5T2 Gene

mRNA/cDNA for OR5T2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5T2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5T2 Gene

No ASD Table

Relevant External Links for OR5T2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5T2 Gene

mRNA expression in normal human tissues for OR5T2 Gene

Protein differential expression in normal tissues for OR5T2 Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR5T2 Gene

SOURCE GeneReport for Unigene cluster for OR5T2 Gene Hs.553627

genes like me logo Genes that share expressions with OR5T2: view

Expression partners for OR5T2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR5T2 Gene

Orthologs for OR5T2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR5T2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC610544 35
  • 85.16 (n)
  • 81.5 (a)
OR5T2 36
  • 80 (a)
(Mus musculus)
Mammalia Olfr1086 35
  • 79.63 (n)
  • 74.84 (a)
Olfr1086 16
Olfr1086 36
  • 74 (a)
Olfr1095 36
  • 75 (a)
Olfr1101 36
  • 74 (a)
Olfr141 36
  • 75 (a)
(Pan troglodytes)
Mammalia LOC466553 35
  • 98.79 (n)
  • 97.21 (a)
OR5T2 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr510 35
  • 79.55 (n)
  • 75.32 (a)
(Bos Taurus)
Mammalia -- 36
  • 79 (a)
-- 36
  • 74 (a)
-- 36
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 64 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 51 (a)
Species with no ortholog for OR5T2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5T2 Gene

Gene Tree for OR5T2 (if available)
Gene Tree for OR5T2 (if available)

Paralogs for OR5T2 Gene

Paralogs for OR5T2 Gene

(424) SIMAP similar genes for OR5T2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5T2: view

Variants for OR5T2 Gene

Sequence variations from dbSNP and Humsavar for OR5T2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs3919907 - 56,233,124(-) TCATT(A/C)TTTTT missense, reference
rs7121880 - 56,232,261(+) GTCAT(C/G)GTCCG reference, missense
rs7122000 -- 56,232,421(+) TAGGA(A/G)ATCAG reference, synonymous-codon
rs7122514 - 56,232,812(+) TTGTC(A/G/T)TAAAA missense, reference
rs10791893 - 56,232,927(+) GACCA(C/G)TAAAA missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR5T2 Gene

Variant ID Type Subtype PubMed ID
nsv521440 CNV Loss 19592680

Relevant External Links for OR5T2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5T2 Gene

Disorders for OR5T2 Gene

No disorders were found for OR5T2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR5T2 Gene

Publications for OR5T2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR5T2 Gene

Sources for OR5T2 Gene

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