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Aliases for OR5P2 Gene

Aliases for OR5P2 Gene

  • Olfactory Receptor, Family 5, Subfamily P, Member 2 2 3
  • Olfactory Receptor-Like Protein JCG3 3 4
  • Olfactory Receptor OR11-93 3
  • Olfactory Receptor 5P2 3
  • JCG3 3
  • JCG4 3

External Ids for OR5P2 Gene

Summaries for OR5P2 Gene

Entrez Gene Summary for OR5P2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5P2 Gene

OR5P2 (Olfactory Receptor, Family 5, Subfamily P, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5P3.

UniProtKB/Swiss-Prot for OR5P2 Gene

  • Odorant receptor (Potential). May be involved in taste perception.

Gene Wiki entry for OR5P2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5P2 Gene

Genomics for OR5P2 Gene

Genomic Location for OR5P2 Gene

Start:
7,795,905 bp from pter
End:
7,796,973 bp from pter
Size:
1,069 bases
Orientation:
Minus strand

Genomic View for OR5P2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5P2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5P2 Gene

Regulatory Elements for OR5P2 Gene

Proteins for OR5P2 Gene

  • Protein details for OR5P2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WZ92-OR5P2_HUMAN
    Recommended name:
    Olfactory receptor 5P2
    Protein Accession:
    Q8WZ92
    Secondary Accessions:
    • Q3MIS8

    Protein attributes for OR5P2 Gene

    Size:
    322 amino acids
    Molecular mass:
    35786 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5P2 Gene

Proteomics data for OR5P2 Gene at MOPED

Post-translational modifications for OR5P2 Gene

Other Protein References for OR5P2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR5P2 Gene

Domains for OR5P2 Gene

Gene Families for OR5P2 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5P2 Gene

Suggested Antigen Peptide Sequences for OR5P2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WZ92

UniProtKB/Swiss-Prot:

OR5P2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8WZ92
genes like me logo Genes that share domains with OR5P2: view

Function for OR5P2 Gene

Molecular function for OR5P2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor (Potential). May be involved in taste perception.

Gene Ontology (GO) - Molecular Function for OR5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5P2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5P2 Gene

Localization for OR5P2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5P2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5P2 Gene COMPARTMENTS Subcellular localization image for OR5P2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5P2: view

Pathways for OR5P2 Gene

genes like me logo Genes that share pathways with OR5P2: view

Pathways by source for OR5P2 Gene

Interacting Proteins for OR5P2 Gene

Gene Ontology (GO) - Biological Process for OR5P2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5P2: view

Transcripts for OR5P2 Gene

mRNA/cDNA for OR5P2 Gene

(1) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5P2 Gene

No ASD Table

Relevant External Links for OR5P2 Gene

GeneLoc Exon Structure for
OR5P2
ECgene alternative splicing isoforms for
OR5P2

Expression for OR5P2 Gene

mRNA expression in normal human tissues for OR5P2 Gene

mRNA differential expression in normal tissues according to GTEx for OR5P2 Gene

This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (13.2), Skin - Sun Exposed (Lower leg) (12.1), and Bladder (10.5).

SOURCE GeneReport for Unigene cluster for OR5P2 Gene Hs.351824

mRNA Expression by UniProt/SwissProt for OR5P2 Gene

Q8WZ92-OR5P2_HUMAN
Tissue specificity: Expressed in the tongue
genes like me logo Genes that share expressions with OR5P2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for OR5P2 Gene

Orthologs for OR5P2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5P2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466430 35
  • 99.07 (n)
  • 98.14 (a)
OR5P2 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 73 (a)
OneToMany
-- 36
  • 79 (a)
OneToMany
LOC516263 35
  • 84.52 (n)
  • 80.97 (a)
dog
(Canis familiaris)
Mammalia LOC100683576 35
  • 84.37 (n)
  • 79.67 (a)
OR5P2 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr469 36
  • 74 (a)
OneToMany
Olfr470 36
  • 72 (a)
OneToMany
Olfr478 36
  • 77 (a)
OneToMany
Olfr482 36
  • 71 (a)
OneToMany
Olfr483 36
  • 72 (a)
OneToMany
Olfr484 36
  • 73 (a)
OneToMany
Olfr486 36
  • 67 (a)
OneToMany
Olfr487 36
  • 67 (a)
OneToMany
Olfr488 36
  • 69 (a)
OneToMany
Olfr490 36
  • 73 (a)
OneToMany
Olfr493 36
  • 75 (a)
OneToMany
Olfr494 36
  • 74 (a)
OneToMany
Olfr495 36
  • 67 (a)
OneToMany
Olfr497 36
  • 72 (a)
OneToMany
Olfr498 36
  • 66 (a)
OneToMany
Olfr502 35
  • 81.87 (n)
  • 80.78 (a)
Olfr502 16
Olfr502 36
  • 79 (a)
OneToMany
Olfr506 36
  • 75 (a)
OneToMany
Olfr507 36
  • 73 (a)
OneToMany
Olfr510 36
  • 72 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 58 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 56 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 53 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 52 (a)
OneToMany
-- 36
  • 55 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr279 35
  • 81.43 (n)
  • 80.46 (a)
Species with no ortholog for OR5P2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5P2 Gene

ENSEMBL:
Gene Tree for OR5P2 (if available)
TreeFam:
Gene Tree for OR5P2 (if available)

Paralogs for OR5P2 Gene

Paralogs for OR5P2 Gene

Selected SIMAP similar genes for OR5P2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5P2: view

Variants for OR5P2 Gene

Sequence variations from dbSNP and Humsavar for OR5P2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs441803 -- 7,795,752(+) AAATG(C/T)TTCAT downstream-variant-500B
rs1482804 - 7,796,924(+) ATTCC(C/T)GTCCT missense, reference
rs1531810 -- 7,798,403(+) AAAAT(G/T)AGCCA upstream-variant-2KB
rs1968857 -- 7,798,573(+) GGGCC(A/G)GGCAT upstream-variant-2KB
rs1968858 -- 7,798,670(+) ACACC(A/G)TGAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5P2 Gene

Variant ID Type Subtype PubMed ID
nsv7215 OTHER Inversion 18451855
nsv499766 OTHER Inversion 21111241
nsv509387 CNV Insertion 20534489
nsv510998 CNV Complex 20534489
nsv896977 CNV Loss 21882294
nsv896978 CNV Loss 21882294
nsv7660 CNV Loss 18451855
nsv896979 CNV Gain 21882294
nsv896980 CNV Loss 21882294
dgv190e199 CNV Deletion 23128226
nsv498751 CNV Loss 21111241
nsv436124 CNV Deletion 17901297
esv22126 CNV Loss 19812545
esv2422018 CNV Deletion 20811451
nsv442601 CNV CNV 18776908
dgv199n67 CNV Loss 20364138
nsv514633 CNV Loss 21397061

Relevant External Links for OR5P2 Gene

HapMap Linkage Disequilibrium report
OR5P2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5P2 Gene

Disorders for OR5P2 Gene

No disorders were found for OR5P2 Gene.

No data available for UniProtKB/Swiss-Prot for OR5P2 Gene

Publications for OR5P2 Gene

  1. New GPCRs from a human lingual cDNA library. (PMID: 11705801) Gaudin J.-C. … Haertle T. (Chem. Senses 2001) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3

Products for OR5P2 Gene

Sources for OR5P2 Gene

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