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Aliases for OR5M3 Gene

Aliases for OR5M3 Gene

  • Olfactory Receptor Family 5 Subfamily M Member 3 2 3 5
  • Olfactory Receptor, Family 5, Subfamily M, Member 3 2 3
  • Olfactory Receptor OR11-191 3 4
  • OR11-191 3

External Ids for OR5M3 Gene

Previous GeneCards Identifiers for OR5M3 Gene

  • GC11U990361
  • GC11M056014
  • GC11M055993
  • GC11M056237

Summaries for OR5M3 Gene

Entrez Gene Summary for OR5M3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5M3 Gene

OR5M3 (Olfactory Receptor Family 5 Subfamily M Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR5M11.

UniProtKB/Swiss-Prot for OR5M3 Gene

  • Odorant receptor.

Gene Wiki entry for OR5M3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5M3 Gene

Genomics for OR5M3 Gene

Regulatory Elements for OR5M3 Gene

Enhancers for OR5M3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR5M3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5M3 Gene

56,469,488 bp from pter
56,470,538 bp from pter
1,051 bases
Minus strand

Genomic View for OR5M3 Gene

Genes around OR5M3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5M3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5M3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5M3 Gene

Proteins for OR5M3 Gene

  • Protein details for OR5M3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5M3
    Protein Accession:
    Secondary Accessions:
    • B2RNM7
    • Q6IEW4
    • Q96RC0

    Protein attributes for OR5M3 Gene

    307 amino acids
    Molecular mass:
    35156 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5M3 Gene

Proteomics data for OR5M3 Gene at MOPED

Post-translational modifications for OR5M3 Gene

  • Glycosylation at Asn 3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5M3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5M3 Gene

Domains & Families for OR5M3 Gene

Gene Families for OR5M3 Gene

Protein Domains for OR5M3 Gene

Suggested Antigen Peptide Sequences for OR5M3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5M3: view

Function for OR5M3 Gene

Molecular function for OR5M3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5M3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5M3: view

Phenotypes for OR5M3 Gene

genes like me logo Genes that share phenotypes with OR5M3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5M3 Gene

Localization for OR5M3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5M3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5M3 Gene COMPARTMENTS Subcellular localization image for OR5M3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5M3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5M3: view

Pathways & Interactions for OR5M3 Gene

genes like me logo Genes that share pathways with OR5M3: view

Pathways by source for OR5M3 Gene

Interacting Proteins for OR5M3 Gene

Gene Ontology (GO) - Biological Process for OR5M3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5M3: view

No data available for SIGNOR curated interactions for OR5M3 Gene

Drugs & Compounds for OR5M3 Gene

No Compound Related Data Available

Transcripts for OR5M3 Gene

mRNA/cDNA for OR5M3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5M3 Gene

No ASD Table

Relevant External Links for OR5M3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5M3 Gene

mRNA expression in normal human tissues for OR5M3 Gene

Protein differential expression in normal tissues from HIPED for OR5M3 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR5M3 Gene

SOURCE GeneReport for Unigene cluster for OR5M3 Gene Hs.553631

genes like me logo Genes that share expression patterns with OR5M3: view

Protein tissue co-expression partners for OR5M3 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR5M3 Gene

Orthologs for OR5M3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5M3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR5M3 35
  • 87.58 (n)
  • 89.54 (a)
OR5M3 36
  • 88 (a)
(Canis familiaris)
Mammalia OR5M3 35
  • 87.73 (n)
  • 90.55 (a)
OR5M3 36
  • 90 (a)
(Mus musculus)
Mammalia Olfr1032 35
  • 85.62 (n)
  • 92.48 (a)
Olfr1032 16
Olfr1032 36
  • 91 (a)
Olfr1033 36
  • 89 (a)
(Rattus norvegicus)
Mammalia Olr473 35
  • 85.73 (n)
  • 92.48 (a)
(Monodelphis domestica)
Mammalia OR5M3 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 58 (a)
Species with no ortholog for OR5M3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5M3 Gene

Gene Tree for OR5M3 (if available)
Gene Tree for OR5M3 (if available)

Paralogs for OR5M3 Gene

Paralogs for OR5M3 Gene

(448) SIMAP similar genes for OR5M3 Gene using alignment to 1 proteins: Pseudogenes for OR5M3 Gene

genes like me logo Genes that share paralogs with OR5M3: view

Variants for OR5M3 Gene

Sequence variations from dbSNP and Humsavar for OR5M3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs605734 - 56,470,246(-) CTGTT(A/G/T)TCAGA reference, missense
rs17150664 - 56,470,011(+) CAAGC(A/C/T)GTAAG reference, missense
rs617315 -- 56,469,934(-) TGTGC(C/T)GGGAC reference, synonymous-codon
rs620166 -- 56,469,301(-) CAACC(A/C)AAAGA downstream-variant-500B
rs625007 -- 56,472,154(+) AGATT(A/G)CATTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5M3 Gene

Variant ID Type Subtype PubMed ID
dgv220n67 CNV Gain 20364138
nsv825910 CNV Gain 20364138
nsv825911 CNV Gain 20364138

Variation tolerance for OR5M3 Gene

Residual Variation Intolerance Score: 97.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.46; 71.57% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR5M3 Gene

Disorders for OR5M3 Gene

Relevant External Links for OR5M3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR5M3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5M3 Gene

Publications for OR5M3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR5M3 Gene

Sources for OR5M3 Gene