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Aliases for OR5M10 Gene

Aliases for OR5M10 Gene

  • Olfactory Receptor Family 5 Subfamily M Member 10 2 3 5
  • Olfactory Receptor OR11-207 3 4
  • Olfactory Receptor, Family 5, Subfamily M, Member 10 2
  • Olfactory Receptor 5M10 3
  • OR11-207 3

External Ids for OR5M10 Gene

Previous GeneCards Identifiers for OR5M10 Gene

  • GC11U990424
  • GC11M056119
  • GC11M056066
  • GC11M056100
  • GC11M056345
  • GC11M056346

Summaries for OR5M10 Gene

Entrez Gene Summary for OR5M10 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5M10 Gene

OR5M10 (Olfactory Receptor Family 5 Subfamily M Member 10) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR5M1.

UniProtKB/Swiss-Prot for OR5M10 Gene

  • Odorant receptor.

Gene Wiki entry for OR5M10 Gene

Additional gene information for OR5M10 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5M10 Gene

Genomics for OR5M10 Gene

Regulatory Elements for OR5M10 Gene

Enhancers for OR5M10 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H056895 0.3 FANTOM5 14.9 -318.0 -318029 0 OR5M10 OR5M9 OR5AP2 OR5M1 OR5M3 OR5AR1 OR5M8 OR5R1 OR5M11 FADS2P1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR5M10 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5M10 Gene

Chromosome:
11
Start:
56,576,736 bp from pter
End:
56,577,787 bp from pter
Size:
1,052 bases
Orientation:
Minus strand

Genomic View for OR5M10 Gene

Genes around OR5M10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5M10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5M10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5M10 Gene

Proteins for OR5M10 Gene

  • Protein details for OR5M10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IEU7-OR5MA_HUMAN
    Recommended name:
    Olfactory receptor 5M10
    Protein Accession:
    Q6IEU7
    Secondary Accessions:
    • B9EIL9

    Protein attributes for OR5M10 Gene

    Size:
    315 amino acids
    Molecular mass:
    35592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5M10 Gene

Post-translational modifications for OR5M10 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR5M10 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5M10 Gene

Domains & Families for OR5M10 Gene

Gene Families for OR5M10 Gene

HGNC:
Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR5M10 Gene

Suggested Antigen Peptide Sequences for OR5M10 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6IEU7

UniProtKB/Swiss-Prot:

OR5MA_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5M10: view

Function for OR5M10 Gene

Molecular function for OR5M10 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5M10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5M10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR5M10
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5M10 Gene

Localization for OR5M10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5M10 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR5M10 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5M10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5M10: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR5M10 Gene

Pathways & Interactions for OR5M10 Gene

genes like me logo Genes that share pathways with OR5M10: view

Pathways by source for OR5M10 Gene

Interacting Proteins for OR5M10 Gene

Gene Ontology (GO) - Biological Process for OR5M10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5M10: view

No data available for SIGNOR curated interactions for OR5M10 Gene

Drugs & Compounds for OR5M10 Gene

No Compound Related Data Available

Transcripts for OR5M10 Gene

mRNA/cDNA for OR5M10 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OR5M10
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OR5M10 Gene

No ASD Table

Relevant External Links for OR5M10 Gene

GeneLoc Exon Structure for
OR5M10
ECgene alternative splicing isoforms for
OR5M10

Expression for OR5M10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR5M10 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR5M10 Gene:

OR5M10

SOURCE GeneReport for Unigene cluster for OR5M10 Gene:

Hs.553750
genes like me logo Genes that share expression patterns with OR5M10: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR5M10 Gene

Orthologs for OR5M10 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5M10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466570 33
  • 98.41 (n)
OR5M10 34
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 34
  • 87 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 83 (a)
ManyToMany
-- 34
  • 83 (a)
ManyToMany
-- 34
  • 79 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Or5m10 52 Olfr1023 34
  • 83 (a)
ManyToMany
Or5m10b 52 Olfr1022 33 16 34
  • 82.21 (n)
rat
(Rattus norvegicus)
Mammalia Olr465 33
  • 82.64 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 78 (a)
ManyToMany
-- 34
  • 75 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 66 (a)
OneToMany
Species where no ortholog for OR5M10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5M10 Gene

ENSEMBL:
Gene Tree for OR5M10 (if available)
TreeFam:
Gene Tree for OR5M10 (if available)

Paralogs for OR5M10 Gene

Paralogs for OR5M10 Gene

(450) SIMAP similar genes for OR5M10 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR5M10 Gene

genes like me logo Genes that share paralogs with OR5M10: view

Variants for OR5M10 Gene

Sequence variations from dbSNP and Humsavar for OR5M10 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1001764636 -- 56,578,461(+) TGAGC(C/T)GAGAT upstream-variant-2KB
rs1003471730 -- 56,577,622(+) GTAGA(G/T)CGCCA reference, missense
rs1005448875 -- 56,579,706(+) TGAGG(G/T)GTAGA upstream-variant-2KB
rs1006054292 -- 56,576,679(+) GGTTA(C/G/T)TAAGA downstream-variant-500B
rs1007716626 -- 56,577,811(+) CATTC(A/G)CTCAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5M10 Gene

Variant ID Type Subtype PubMed ID
dgv69n21 CNV loss 19592680
esv2421725 CNV deletion 20811451
esv2760201 CNV loss 21179565
esv3626481 CNV loss 21293372
nsv1037096 CNV loss 25217958
nsv516558 CNV loss 19592680
nsv555099 CNV loss 21841781
nsv971950 OTHER complex 23825009

Variation tolerance for OR5M10 Gene

Residual Variation Intolerance Score: 70.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.25; 62.42% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR5M10 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR5M10

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5M10 Gene

Disorders for OR5M10 Gene

Relevant External Links for OR5M10

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR5M10

No disorders were found for OR5M10 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5M10 Gene

Publications for OR5M10 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 3 4 60
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for OR5M10 Gene

Sources for OR5M10 Gene

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