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Aliases for OR5M1 Gene

Aliases for OR5M1 Gene

  • Olfactory Receptor, Family 5, Subfamily M, Member 1 2 3
  • Olfactory Receptor OR11-208 3 4
  • OST050 3 4
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor 5M1 3
  • OR11-208 3

External Ids for OR5M1 Gene

Summaries for OR5M1 Gene

Entrez Gene Summary for OR5M1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5M1 Gene

OR5M1 (Olfactory Receptor, Family 5, Subfamily M, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5M11.

UniProtKB/Swiss-Prot for OR5M1 Gene

  • Odorant receptor.

Gene Wiki entry for OR5M1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5M1 Gene

Genomics for OR5M1 Gene

Genomic Location for OR5M1 Gene

Start:
56,612,555 bp from pter
End:
56,613,502 bp from pter
Size:
948 bases
Orientation:
Minus strand

Genomic View for OR5M1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5M1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5M1 Gene

Regulatory Elements for OR5M1 Gene

Proteins for OR5M1 Gene

  • Protein details for OR5M1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGP8-OR5M1_HUMAN
    Recommended name:
    Olfactory receptor 5M1
    Protein Accession:
    Q8NGP8
    Secondary Accessions:
    • Q6IF60
    • Q96RB6

    Protein attributes for OR5M1 Gene

    Size:
    315 amino acids
    Molecular mass:
    35608 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5M1 Gene

Proteomics data for OR5M1 Gene at MOPED

Post-translational modifications for OR5M1 Gene

Other Protein References for OR5M1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR5M1 Gene

Domains for OR5M1 Gene

Gene Families for OR5M1 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5M1 Gene

UniProtKB/Swiss-Prot:

OR5M1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGP8
genes like me logo Genes that share domains with OR5M1: view

Function for OR5M1 Gene

Molecular function for OR5M1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5M1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5M1 Gene

Localization for OR5M1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5M1 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR5M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5M1: view

Pathways for OR5M1 Gene

genes like me logo Genes that share pathways with OR5M1: view

Pathways by source for OR5M1 Gene

Interacting Proteins for OR5M1 Gene

Gene Ontology (GO) - Biological Process for OR5M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5M1: view

Transcripts for OR5M1 Gene

mRNA/cDNA for OR5M1 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5M1 Gene

No ASD Table

Relevant External Links for OR5M1 Gene

GeneLoc Exon Structure for
OR5M1
ECgene alternative splicing isoforms for
OR5M1

Expression for OR5M1 Gene

mRNA expression in normal human tissues for OR5M1 Gene

SOURCE GeneReport for Unigene cluster for OR5M1 Gene Hs.553751

genes like me logo Genes that share expressions with OR5M1: view

Orthologs for OR5M1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5M1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466572 36
  • 99.05 (n)
  • 98.73 (a)
OR5M1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 83 (a)
ManyToMany
-- 37
  • 78 (a)
ManyToMany
-- 37
  • 82 (a)
ManyToMany
OR5M10 36
  • 86.38 (n)
  • 83.99 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 86 (a)
OneToMany
LOC100684561 36
  • 86.67 (n)
  • 86.03 (a)
mouse
(Mus musculus)
Mammalia Olfr1022 37
  • 80 (a)
ManyToMany
Olfr1023 36
  • 82.74 (n)
  • 83.39 (a)
Olfr1023 16
Olfr1023 37
  • 83 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 74 (a)
ManyToMany
-- 37
  • 77 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 65 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr466 36
  • 84.1 (n)
  • 84.21 (a)
Species with no ortholog for OR5M1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5M1 Gene

ENSEMBL:
Gene Tree for OR5M1 (if available)
TreeFam:
Gene Tree for OR5M1 (if available)

Paralogs for OR5M1 Gene

Paralogs for OR5M1 Gene

Selected SIMAP similar genes for OR5M1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5M1: view

Variants for OR5M1 Gene

Sequence variations from dbSNP and Humsavar for OR5M1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1001967 -- 56,612,252(-) CTTAG(C/G)CTGAG downstream-variant-500B
rs2019246 -- 56,612,533(-) AGTCA(A/C/T)GAATT downstream-variant-500B
rs3071382 -- 56,614,817(+) ACACA(-/CA/CACA/CACACA)AATTG upstream-variant-2KB
rs4939078 - 56,612,658(+) TTGGG(C/G)TCAAA missense, reference
rs11228681 -- 56,615,482(+) TAAAA(C/T)TGATG upstream-variant-2KB

Relevant External Links for OR5M1 Gene

HapMap Linkage Disequilibrium report
OR5M1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR5M1 Gene

Disorders for OR5M1 Gene

No disorders were found for OR5M1 Gene.

No data available for UniProtKB/Swiss-Prot for OR5M1 Gene

Publications for OR5M1 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR5M1 Gene

Sources for OR5M1 Gene

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