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Aliases for OR5K1 Gene

Aliases for OR5K1 Gene

  • Olfactory Receptor, Family 5, Subfamily K, Member 1 2 3
  • Olfactory Receptor OR3-8 3 4
  • HTPCRX10 3 4
  • Olfactory Receptor 5K1 3
  • HSHTPCRX10 3
  • OR3-8 3

External Ids for OR5K1 Gene

Summaries for OR5K1 Gene

Entrez Gene Summary for OR5K1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5K1 Gene

OR5K1 (Olfactory Receptor, Family 5, Subfamily K, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5H14.

UniProtKB/Swiss-Prot for OR5K1 Gene

  • Odorant receptor.

Gene Wiki entry for OR5K1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5K1 Gene

Genomics for OR5K1 Gene

Genomic Location for OR5K1 Gene

Start:
98,469,480 bp from pter
End:
98,470,576 bp from pter
Size:
1,097 bases
Orientation:
Plus strand

Genomic View for OR5K1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5K1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5K1 Gene

Regulatory Elements for OR5K1 Gene

Proteins for OR5K1 Gene

  • Protein details for OR5K1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NHB7-OR5K1_HUMAN
    Recommended name:
    Olfactory receptor 5K1
    Protein Accession:
    Q8NHB7
    Secondary Accessions:
    • B9EGY5
    • Q6IF46

    Protein attributes for OR5K1 Gene

    Size:
    308 amino acids
    Molecular mass:
    35185 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05718.1; Type=Frameshift; Positions=308; Evidence={ECO:0000305};

neXtProt entry for OR5K1 Gene

Proteomics data for OR5K1 Gene at MOPED

Post-translational modifications for OR5K1 Gene

Other Protein References for OR5K1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR5K1 Gene

Domains for OR5K1 Gene

Gene Families for OR5K1 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5K1 Gene

UniProtKB/Swiss-Prot:

OR5K1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NHB7
genes like me logo Genes that share domains with OR5K1: view

Function for OR5K1 Gene

Molecular function for OR5K1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5K1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5K1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5K1 Gene

Localization for OR5K1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5K1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5K1 Gene COMPARTMENTS Subcellular localization image for OR5K1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5K1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5K1: view

Pathways for OR5K1 Gene

genes like me logo Genes that share pathways with OR5K1: view

Pathways by source for OR5K1 Gene

Interacting Proteins for OR5K1 Gene

Gene Ontology (GO) - Biological Process for OR5K1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5K1: view

Transcripts for OR5K1 Gene

mRNA/cDNA for OR5K1 Gene

(1) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5K1 Gene

No ASD Table

Relevant External Links for OR5K1 Gene

GeneLoc Exon Structure for
OR5K1
ECgene alternative splicing isoforms for
OR5K1

Expression for OR5K1 Gene

mRNA expression in normal human tissues for OR5K1 Gene

SOURCE GeneReport for Unigene cluster for OR5K1 Gene Hs.621533

genes like me logo Genes that share expressions with OR5K1: view

Orthologs for OR5K1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5K1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC470870 36
  • 99.13 (n)
  • 99.03 (a)
cow
(Bos Taurus)
Mammalia -- 37
  • 83 (a)
OneToMany
OR5K1 36
  • 88.2 (n)
  • 87.01 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 84 (a)
OneToMany
LOC100856070 36
  • 87.77 (n)
  • 87.34 (a)
mouse
(Mus musculus)
Mammalia Olfr172 16
Olfr172 37
  • 82 (a)
ManyToMany
Olfr173 36
  • 84.09 (n)
  • 85.06 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 68 (a)
ManyToMany
-- 37
  • 66 (a)
ManyToMany
-- 37
  • 68 (a)
ManyToMany
Species with no ortholog for OR5K1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5K1 Gene

ENSEMBL:
Gene Tree for OR5K1 (if available)
TreeFam:
Gene Tree for OR5K1 (if available)

Paralogs for OR5K1 Gene

Paralogs for OR5K1 Gene

Selected SIMAP similar genes for OR5K1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5K1: view

Variants for OR5K1 Gene

Sequence variations from dbSNP and Humsavar for OR5K1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs4857390 -- 98,468,733(+) TTTGG(G/T)TTGCT upstream-variant-2KB
rs6785945 -- 98,469,177(+) TAATG(A/G)AGGAA upstream-variant-2KB
rs9861575 -- 98,469,521(+) CTGTG(C/G)CATAT upstream-variant-2KB
rs12632043 -- 98,470,973(+) AGCAA(C/T)AAAAT downstream-variant-500B
rs34478238 -- 98,469,771(+) GAAAT(-/G)CTGGC reference, frameshift-variant

Structural Variations from Database of Genomic Variants (DGV) for OR5K1 Gene

Variant ID Type Subtype PubMed ID
dgv293n21 CNV Loss 19592680
nsv834774 CNV Loss 17160897
nsv834775 CNV Gain 17160897

Relevant External Links for OR5K1 Gene

HapMap Linkage Disequilibrium report
OR5K1

Disorders for OR5K1 Gene

No disorders were found for OR5K1 Gene.

No data available for UniProtKB/Swiss-Prot for OR5K1 Gene

Publications for OR5K1 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR5K1 Gene

Sources for OR5K1 Gene

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