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Aliases for OR5H1 Gene

Aliases for OR5H1 Gene

  • Olfactory Receptor, Family 5, Subfamily H, Member 1 2 3
  • HTPCRX14 3 4
  • Olfactory Receptor 5H1 3
  • HSHTPCRX14 3

External Ids for OR5H1 Gene

Previous GeneCards Identifiers for OR5H1 Gene

  • GC03P094471
  • GC03P097190
  • GC03P099132
  • GC03U900512
  • GC03P099335
  • GC03P097851

Summaries for OR5H1 Gene

Entrez Gene Summary for OR5H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5H1 Gene

OR5H1 (Olfactory Receptor, Family 5, Subfamily H, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5H14.

UniProtKB/Swiss-Prot for OR5H1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5H1 Gene

Genomics for OR5H1 Gene

Regulatory Elements for OR5H1 Gene

Genomic Location for OR5H1 Gene

98,132,698 bp from pter
98,133,639 bp from pter
942 bases
Plus strand

Genomic View for OR5H1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5H1 Gene

Proteins for OR5H1 Gene

  • Protein details for OR5H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5H1
    Protein Accession:
    Secondary Accessions:

    Protein attributes for OR5H1 Gene

    313 amino acids
    Molecular mass:
    35387 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5H1 Gene

Proteomics data for OR5H1 Gene at MOPED

Post-translational modifications for OR5H1 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5H1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for OR5H1

No data available for DME Specific Peptides for OR5H1 Gene

Domains for OR5H1 Gene

Gene Families for OR5H1 Gene

Protein Domains for OR5H1 Gene

Suggested Antigen Peptide Sequences for OR5H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5H1: view

Function for OR5H1 Gene

Molecular function for OR5H1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5H1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5H1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5H1 Gene

Localization for OR5H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5H1 Gene COMPARTMENTS Subcellular localization image for OR5H1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5H1: view

Pathways for OR5H1 Gene

genes like me logo Genes that share pathways with OR5H1: view

Pathways by source for OR5H1 Gene

Interacting Proteins for OR5H1 Gene

Gene Ontology (GO) - Biological Process for OR5H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5H1: view

Transcripts for OR5H1 Gene

mRNA/cDNA for OR5H1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5H1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5H1 Gene

No ASD Table

Relevant External Links for OR5H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5H1 Gene

mRNA expression in normal human tissues for OR5H1 Gene

SOURCE GeneReport for Unigene cluster for OR5H1 Gene Hs.537383

genes like me logo Genes that share expressions with OR5H1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR5H1 Gene

Orthologs for OR5H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC789957 35
  • 82.64 (n)
  • 77 (a)
-- 36
  • 72 (a)
-- 36
  • 72 (a)
-- 36
  • 76 (a)
(Canis familiaris)
Mammalia LOC100684793 35
  • 80.84 (n)
  • 77.92 (a)
-- 36
  • 78 (a)
(Rattus norvegicus)
Mammalia Olr1541 35
  • 79.98 (n)
  • 73.7 (a)
(Mus musculus)
Mammalia Olfr196 16
Olfr183 36
  • 75 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
Species with no ortholog for OR5H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5H1 Gene

Gene Tree for OR5H1 (if available)
Gene Tree for OR5H1 (if available)

Paralogs for OR5H1 Gene

Paralogs for OR5H1 Gene

(451) SIMAP similar genes for OR5H1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5H1: view

Variants for OR5H1 Gene

Sequence variations from dbSNP and Humsavar for OR5H1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs5009896 - 98,133,139(+) TCTTG(C/T)CATAT missense, reference
rs5009897 -- 98,133,048(+) GCAAC(A/G)ATGGC synonymous-codon, reference
rs9826076 - 98,133,239(+) TGACA(C/T)TATCC reference, missense
rs9845327 - 98,133,154(+) GTGGT(A/C)TTCTT reference, missense
rs9849637 - 98,133,385(+) AGAAA(A/T)CTGAT missense, reference

Structural Variations from Database of Genomic Variants (DGV) for OR5H1 Gene

Variant ID Type Subtype PubMed ID
nsv877207 CNV Gain 21882294
nsv877209 CNV Gain 21882294
dgv823e201 CNV Deletion 23290073
esv2677041 CNV Deletion 23128226
dgv824e201 CNV Deletion 23290073

Relevant External Links for OR5H1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5H1 Gene

Disorders for OR5H1 Gene

No disorders were found for OR5H1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR5H1 Gene

Publications for OR5H1 Gene

  1. Expression of members of the putative olfactory receptor gene family in mammalian germ cells. (PMID: 1370859) Parmentier M. … Vassart G. (Nature 1992) 2 3 4
  2. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4

Products for OR5H1 Gene

Sources for OR5H1 Gene

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