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Aliases for OR5G3 Gene

Aliases for OR5G3 Gene

  • Olfactory Receptor Family 5 Subfamily G Member 3 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 5, Subfamily G, Member 3 Pseudogene 2 3
  • OR5G3P 3 4
  • OR5G6P 3 4
  • Olfactory Receptor, Family 5, Subfamily G, Member 3 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 5, Subfamily G, Member 6 Pseudogene 3
  • Olfactory Receptor OR11-213 4
  • Olfactory Receptor 5G3 3
  • Olfactory Receptor 5G6 4

External Ids for OR5G3 Gene

Previous HGNC Symbols for OR5G3 Gene

  • OR5G6P
  • OR5G3P

Previous GeneCards Identifiers for OR5G3 Gene

  • GC11U990427
  • GC11M056344
  • GC11M056586

Summaries for OR5G3 Gene

Entrez Gene Summary for OR5G3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

GeneCards Summary for OR5G3 Gene

OR5G3 (Olfactory Receptor Family 5 Subfamily G Member 3 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5J2.

UniProtKB/Swiss-Prot for OR5G3 Gene

  • Odorant receptor.

Additional gene information for OR5G3 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5G3 Gene

Genomics for OR5G3 Gene

Regulatory Elements for OR5G3 Gene

Enhancers for OR5G3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H056841 0.6 ENCODE 0.3 -20.8 -20794 0 CTCF ZNF654 TRIM22 REST RAD21 MAFF ZNF143 SMC3 EMSY MAFK LOC101927120 OR5G3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR5G3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5G3 Gene

Chromosome:
11
Start:
56,819,479 bp from pter
End:
56,820,646 bp from pter
Size:
1,168 bases
Orientation:
Minus strand

Genomic View for OR5G3 Gene

Genes around OR5G3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5G3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5G3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5G3 Gene

Proteins for OR5G3 Gene

  • Protein details for OR5G3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C626-OR5G3_HUMAN
    Recommended name:
    Olfactory receptor 5G3
    Protein Accession:
    P0C626

    Protein attributes for OR5G3 Gene

    Size:
    314 amino acids
    Molecular mass:
    35647 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5G3 Gene

Post-translational modifications for OR5G3 Gene

Other Protein References for OR5G3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for OR5G3 Gene

Domains & Families for OR5G3 Gene

Gene Families for OR5G3 Gene

Protein Domains for OR5G3 Gene

Suggested Antigen Peptide Sequences for OR5G3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C626

UniProtKB/Swiss-Prot:

OR5G3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5G3: view

Function for OR5G3 Gene

Molecular function for OR5G3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5G3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5G3: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for OR5G3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5G3 Gene

Localization for OR5G3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5G3 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR5G3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5G3: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for OR5G3 Gene

Pathways & Interactions for OR5G3 Gene

genes like me logo Genes that share pathways with OR5G3: view

Pathways by source for OR5G3 Gene

Interacting Proteins for OR5G3 Gene

Gene Ontology (GO) - Biological Process for OR5G3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5G3: view

No data available for SIGNOR curated interactions for OR5G3 Gene

Drugs & Compounds for OR5G3 Gene

No Compound Related Data Available

Transcripts for OR5G3 Gene

mRNA/cDNA for OR5G3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for OR5G3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OR5G3 Gene

No ASD Table

Relevant External Links for OR5G3 Gene

GeneLoc Exon Structure for
OR5G3
ECgene alternative splicing isoforms for
OR5G3

Expression for OR5G3 Gene

Protein differential expression in normal tissues from HIPED for OR5G3 Gene

This gene is overexpressed in Spleen (49.7) and Testis (19.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OR5G3 Gene



Protein tissue co-expression partners for OR5G3 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR5G3 Gene:

OR5G3

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR5G3 Gene

Orthologs for OR5G3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5G3 Gene

Organism Taxonomy Gene Similarity Type Details
platypus
(Ornithorhynchus anatinus)
Mammalia OR5G3 34
  • 55 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or5g23 52 Olfr1000
  • chr2:85,607,967-85,608,908
Or5g24-ps 52 Olfr1001-ps1
  • chr2:85,633,431-85,634,369
Or5g27 52 Olfr996
  • chr2:85,579,241-85,580,182
Or5g28-ps 52 Olfr997-ps1
  • chr2:85,585,104-85,586,027
Or5g29 52 Olfr998
  • chr2:85,590,542-85,591,483
Or5g30-ps 52 Olfr999-ps1
  • chr2:85,601,772-85,602,717
Species where no ortholog for OR5G3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5G3 Gene

ENSEMBL:
Gene Tree for OR5G3 (if available)
TreeFam:
Gene Tree for OR5G3 (if available)

Paralogs for OR5G3 Gene

Paralogs for OR5G3 Gene

(458) SIMAP similar genes for OR5G3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5G3: view

Variants for OR5G3 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR5G3 Gene

OR5G3_HUMAN-P0C626
A single nucleotide deletion at position Leu-135 in the gene coding for this protein produces a stop codon which is responsible for functional diversity thus producing a pseudogene.

Relevant External Links for OR5G3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR5G3

No data available for Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for OR5G3 Gene

Disorders for OR5G3 Gene

Relevant External Links for OR5G3

Genetic Association Database (GAD)
OR5G3

No disorders were found for OR5G3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5G3 Gene

Publications for OR5G3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 60
  2. Different noses for different people. (PMID: 12730696) Menashe I … Gilad Y (Nature genetics 2003) 3 4 60
  3. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T … Lancet D (BMC genomics 2012) 3 60

Products for OR5G3 Gene

Sources for OR5G3 Gene

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