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Aliases for OR5F1 Gene

Aliases for OR5F1 Gene

  • Olfactory Receptor, Family 5, Subfamily F, Member 1 2 3
  • Olfactory Receptor OR11-167 3 4
  • Olfactory Receptor 11-10 3 4
  • OR11-10 3 4
  • Olfactory Receptor 5F1 3

External Ids for OR5F1 Gene

Previous GeneCards Identifiers for OR5F1 Gene

  • GC11M058154
  • GC11M057274
  • GC11M055536
  • GC11M055517
  • GC11M055761

Summaries for OR5F1 Gene

Entrez Gene Summary for OR5F1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5F1 Gene

OR5F1 (Olfactory Receptor, Family 5, Subfamily F, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR8H2.

UniProtKB/Swiss-Prot for OR5F1 Gene

  • Odorant receptor.

Gene Wiki entry for OR5F1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5F1 Gene

Genomics for OR5F1 Gene

Regulatory Elements for OR5F1 Gene

Genomic Location for OR5F1 Gene

Start:
55,993,681 bp from pter
End:
55,994,625 bp from pter
Size:
945 bases
Orientation:
Minus strand

Genomic View for OR5F1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5F1 Gene

Proteins for OR5F1 Gene

  • Protein details for OR5F1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95221-OR5F1_HUMAN
    Recommended name:
    Olfactory receptor 5F1
    Protein Accession:
    O95221
    Secondary Accessions:
    • Q495D1
    • Q6IFB9

    Protein attributes for OR5F1 Gene

    Size:
    314 amino acids
    Molecular mass:
    35132 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5F1 Gene

Proteomics data for OR5F1 Gene at MOPED

Post-translational modifications for OR5F1 Gene

  • Glycosylation at Asn5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5F1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5F1 Gene

Domains for OR5F1 Gene

Gene Families for OR5F1 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5F1 Gene

Suggested Antigen Peptide Sequences for OR5F1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O95221

UniProtKB/Swiss-Prot:

OR5F1_HUMAN :
  • O95221
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5F1: view

Function for OR5F1 Gene

Molecular function for OR5F1 Gene

GENATLAS Biochemistry: olfactory receptor,family 5,subfamily F,member 1,G protein coupled receptor superfamily
UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9787077
genes like me logo Genes that share ontologies with OR5F1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5F1 Gene

Localization for OR5F1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5F1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5F1 Gene COMPARTMENTS Subcellular localization image for OR5F1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 9787077
genes like me logo Genes that share ontologies with OR5F1: view

Pathways for OR5F1 Gene

genes like me logo Genes that share pathways with OR5F1: view

Pathways by source for OR5F1 Gene

1 KEGG pathway for OR5F1 Gene

Interacting Proteins for OR5F1 Gene

Gene Ontology (GO) - Biological Process for OR5F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 9787077
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9787077
genes like me logo Genes that share ontologies with OR5F1: view

Transcripts for OR5F1 Gene

mRNA/cDNA for OR5F1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5F1 Gene

No ASD Table

Relevant External Links for OR5F1 Gene

GeneLoc Exon Structure for
OR5F1
ECgene alternative splicing isoforms for
OR5F1

Expression for OR5F1 Gene

mRNA expression in normal human tissues for OR5F1 Gene

SOURCE GeneReport for Unigene cluster for OR5F1 Gene Hs.553702

genes like me logo Genes that share expressions with OR5F1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR5F1 Gene

Orthologs for OR5F1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR5F1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC747344 35
  • 98.09 (n)
  • 96.5 (a)
OR5F1 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 83 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
dog
(Canis familiaris)
Mammalia OR5F1 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1323 16
Olfr1323 36
  • 50 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
OneToMany
OPOR117 36
  • 75 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 53 (a)
ManyToMany
chicken
(Gallus gallus)
Aves COR3 36
  • 51 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 55 (a)
OneToMany
-- 36
  • 54 (a)
OneToMany
Species with no ortholog for OR5F1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5F1 Gene

ENSEMBL:
Gene Tree for OR5F1 (if available)
TreeFam:
Gene Tree for OR5F1 (if available)

Paralogs for OR5F1 Gene

Selected SIMAP similar genes for OR5F1 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR5F1 Gene

genes like me logo Genes that share paralogs with OR5F1: view

Variants for OR5F1 Gene

Sequence variations from dbSNP and Humsavar for OR5F1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2128152 -- 55,994,262(+) ATACC(G/T)GTCAT reference, synonymous-codon
rs2449134 - 55,993,745(-) CAGGA(A/G)TAAGG missense, reference
rs2512749 -- 55,996,450(+) AAGCA(C/T)GTAGG upstream-variant-2KB
rs7104912 -- 55,996,259(+) AACTG(C/T)TGGTA upstream-variant-2KB
rs7105199 -- 55,996,467(+) CAGCA(G/T)CTAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5F1 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
nsv437718 CNV Loss 16327808
nsv468568 CNV Loss 19166990
nsv469959 CNV Loss 18288195
nsv517590 CNV Loss 19592680
dgv52e55 CNV Loss 17911159
dgv384e1 CNV Complex 17122850
esv2666045 CNV Deletion 23128226

Relevant External Links for OR5F1 Gene

HapMap Linkage Disequilibrium report
OR5F1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5F1 Gene

Disorders for OR5F1 Gene

No disorders were found for OR5F1 Gene.

No data available for UniProtKB/Swiss-Prot for OR5F1 Gene

Publications for OR5F1 Gene

  1. Organization and evolution of olfactory receptor genes on human chromosome 11. (PMID: 9787077) Buettner J.A. … Evans G.A. (Genomics 1998) 2 3 4
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  3. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR5F1 Gene

Sources for OR5F1 Gene

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