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Aliases for OR5D16 Gene

Aliases for OR5D16 Gene

  • Olfactory Receptor Family 5 Subfamily D Member 16 2 3 5
  • Olfactory Receptor, Family 5, Subfamily D, Member 16 2 3
  • Olfactory Receptor OR11-154 3 4
  • OR11-154 3

External Ids for OR5D16 Gene

Previous GeneCards Identifiers for OR5D16 Gene

  • GC11U990431
  • GC11P055382
  • GC11P055365
  • GC11P055607

Summaries for OR5D16 Gene

Entrez Gene Summary for OR5D16 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5D16 Gene

OR5D16 (Olfactory Receptor Family 5 Subfamily D Member 16) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is ENSG00000279761.

UniProtKB/Swiss-Prot for OR5D16 Gene

  • Odorant receptor.

Gene Wiki entry for OR5D16 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5D16 Gene

Genomics for OR5D16 Gene

Regulatory Elements for OR5D16 Gene

Genomic Location for OR5D16 Gene

Chromosome:
11
Start:
55,838,752 bp from pter
End:
55,839,738 bp from pter
Size:
987 bases
Orientation:
Plus strand

Genomic View for OR5D16 Gene

Genes around OR5D16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5D16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5D16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5D16 Gene

Proteins for OR5D16 Gene

  • Protein details for OR5D16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGK9-OR5DG_HUMAN
    Recommended name:
    Olfactory receptor 5D16
    Protein Accession:
    Q8NGK9
    Secondary Accessions:
    • Q6IF65
    • Q96RB4

    Protein attributes for OR5D16 Gene

    Size:
    328 amino acids
    Molecular mass:
    37278 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5D16 Gene

Proteomics data for OR5D16 Gene at MOPED

Post-translational modifications for OR5D16 Gene

Other Protein References for OR5D16 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5D16 Gene

Domains & Families for OR5D16 Gene

Gene Families for OR5D16 Gene

Protein Domains for OR5D16 Gene

Suggested Antigen Peptide Sequences for OR5D16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGK9

UniProtKB/Swiss-Prot:

OR5DG_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5D16: view

Function for OR5D16 Gene

Molecular function for OR5D16 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5D16: view

Phenotypes for OR5D16 Gene

MGI mutant phenotypes for OR5D16:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with OR5D16: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5D16 Gene

Localization for OR5D16 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5D16 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5D16 Gene COMPARTMENTS Subcellular localization image for OR5D16 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5D16: view

Pathways & Interactions for OR5D16 Gene

genes like me logo Genes that share pathways with OR5D16: view

Pathways by source for OR5D16 Gene

Interacting Proteins for OR5D16 Gene

Gene Ontology (GO) - Biological Process for OR5D16 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5D16: view

No data available for SIGNOR curated interactions for OR5D16 Gene

Drugs & Compounds for OR5D16 Gene

No Compound Related Data Available

Transcripts for OR5D16 Gene

mRNA/cDNA for OR5D16 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5D16 Gene

No ASD Table

Relevant External Links for OR5D16 Gene

GeneLoc Exon Structure for
OR5D16
ECgene alternative splicing isoforms for
OR5D16

Expression for OR5D16 Gene

mRNA expression in normal human tissues for OR5D16 Gene

SOURCE GeneReport for Unigene cluster for OR5D16 Gene Hs.554527

genes like me logo Genes that share expression patterns with OR5D16: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR5D16 Gene

Orthologs for OR5D16 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5D16 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR5D18 35
  • 82.42 (n)
  • 78.14 (a)
-- 36
  • 62 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 60 (a)
ManyToMany
OR5D18 35
  • 83.92 (n)
  • 81.35 (a)
mouse
(Mus musculus)
Mammalia Olfr73 35
  • 77.49 (n)
  • 78.14 (a)
Olfr73 16
Olfr1155 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC686683 35
  • 78.67 (n)
  • 76.85 (a)
Species with no ortholog for OR5D16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5D16 Gene

ENSEMBL:
Gene Tree for OR5D16 (if available)
TreeFam:
Gene Tree for OR5D16 (if available)

Paralogs for OR5D16 Gene

(441) SIMAP similar genes for OR5D16 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5D16: view

Variants for OR5D16 Gene

Sequence variations from dbSNP and Humsavar for OR5D16 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs6591700 - 55,839,217(+) GAGTC(A/G/T)CATGT reference, missense
rs7105503 -- 55,838,380(+) AAATA(C/G)TTATT upstream-variant-2KB
rs10792360 -- 55,836,936(+) TCTAG(C/T)GGATG upstream-variant-2KB
rs10897297 -- 55,838,278(+) CTATA(A/T)CACAA upstream-variant-2KB
rs11231253 -- 55,839,342(+) CTCAG(C/T)CAGTT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR5D16 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
esv782 CNV CNV 17122850
nsv428256 CNV Loss 18775914
nsv437717 CNV Loss 16327808
dgv382e1 CNV Complex 17122850
dgv50e55 CNV Loss 17911159
dgv383e1 CNV Complex 17122850
dgv51e55 CNV Loss 17911159
nsv469885 CNV Loss 16826518
nsv832158 CNV Gain 17160897

Variation tolerance for OR5D16 Gene

Residual Variation Intolerance Score: 56.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.67; 65.87% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR5D16 Gene

HapMap Linkage Disequilibrium report
OR5D16

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5D16 Gene

Disorders for OR5D16 Gene

Relevant External Links for OR5D16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR5D16

No disorders were found for OR5D16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5D16 Gene

Publications for OR5D16 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3

Products for OR5D16 Gene

Sources for OR5D16 Gene

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