Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR5D13 Gene

Aliases for OR5D13 Gene

  • Olfactory Receptor Family 5 Subfamily D Member 13 (Gene/Pseudogene) 2 3 5
  • Olfactory Receptor, Family 5, Subfamily D, Member 13 (Gene/Pseudogene) 2
  • Olfactory Receptor OR11-142 4
  • Olfactory Receptor OR11-148 4

External Ids for OR5D13 Gene

Previous GeneCards Identifiers for OR5D13 Gene

  • GC11U990434
  • GC11P055298
  • GC11P055540

Summaries for OR5D13 Gene

Entrez Gene Summary for OR5D13 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]

GeneCards Summary for OR5D13 Gene

OR5D13 (Olfactory Receptor Family 5 Subfamily D Member 13 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is ENSG00000279761.

UniProtKB/Swiss-Prot for OR5D13 Gene

  • Odorant receptor.

Gene Wiki entry for OR5D13 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5D13 Gene

Genomics for OR5D13 Gene

Regulatory Elements for OR5D13 Gene

Genomic Location for OR5D13 Gene

Chromosome:
11
Start:
55,773,438 bp from pter
End:
55,774,382 bp from pter
Size:
945 bases
Orientation:
Plus strand

Genomic View for OR5D13 Gene

Genes around OR5D13 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5D13 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5D13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5D13 Gene

Proteins for OR5D13 Gene

  • Protein details for OR5D13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGL4-OR5DD_HUMAN
    Recommended name:
    Olfactory receptor 5D13
    Protein Accession:
    Q8NGL4
    Secondary Accessions:
    • Q6IF68
    • Q6IFC9

    Protein attributes for OR5D13 Gene

    Size:
    314 amino acids
    Molecular mass:
    35447 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05998.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR5D13 Gene

Proteomics data for OR5D13 Gene at MOPED

Post-translational modifications for OR5D13 Gene

  • Glycosylation at Asn 7
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5D13 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5D13 Gene

Domains & Families for OR5D13 Gene

Gene Families for OR5D13 Gene

Protein Domains for OR5D13 Gene

Suggested Antigen Peptide Sequences for OR5D13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGL4

UniProtKB/Swiss-Prot:

OR5DD_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5D13: view

Function for OR5D13 Gene

Molecular function for OR5D13 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5D13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5D13: view

Phenotypes for OR5D13 Gene

genes like me logo Genes that share phenotypes with OR5D13: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5D13 Gene

Localization for OR5D13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5D13 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5D13 Gene COMPARTMENTS Subcellular localization image for OR5D13 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5D13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5D13: view

Pathways & Interactions for OR5D13 Gene

genes like me logo Genes that share pathways with OR5D13: view

Pathways by source for OR5D13 Gene

Interacting Proteins for OR5D13 Gene

Gene Ontology (GO) - Biological Process for OR5D13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5D13: view

No data available for SIGNOR curated interactions for OR5D13 Gene

Drugs & Compounds for OR5D13 Gene

No Compound Related Data Available

Transcripts for OR5D13 Gene

mRNA/cDNA for OR5D13 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5D13 Gene

No ASD Table

Relevant External Links for OR5D13 Gene

GeneLoc Exon Structure for
OR5D13
ECgene alternative splicing isoforms for
OR5D13

Expression for OR5D13 Gene

mRNA expression in normal human tissues for OR5D13 Gene

Protein differential expression in normal tissues from HIPED for OR5D13 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR5D13 Gene



SOURCE GeneReport for Unigene cluster for OR5D13 Gene Hs.553743

genes like me logo Genes that share expression patterns with OR5D13: view

Protein tissue co-expression partners for OR5D13 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR5D13 Gene

Orthologs for OR5D13 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5D13 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC739012 35
  • 98.73 (n)
  • 97.13 (a)
OR5D13 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR5D13 36
  • 67 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR5D13 36
  • 67 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 65 (a)
OneToMany
-- 36
  • 65 (a)
OneToMany
OPOR120 36
  • 65 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr1167 36
  • 57 (a)
OneToMany
Species with no ortholog for OR5D13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5D13 Gene

ENSEMBL:
Gene Tree for OR5D13 (if available)
TreeFam:
Gene Tree for OR5D13 (if available)

Paralogs for OR5D13 Gene

(446) SIMAP similar genes for OR5D13 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR5D13 Gene

genes like me logo Genes that share paralogs with OR5D13: view

Variants for OR5D13 Gene

Sequence variations from dbSNP and Humsavar for OR5D13 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs297118 - 55,773,622(-) AAAAG(C/T)ACATG reference, missense
rs11230983 - 55,773,808(+) TGACC(A/G/T)TTTTG reference, missense
rs7124871 - 55,774,144(+) TGGGC(A/G/T)CCAGA reference, missense
rs297119 -- 55,774,785(+) CAACC(A/C/G)TTTAC downstream-variant-500B
rs297116 -- 55,772,583(-) TATGT(A/G)CTAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5D13 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv821668 CNV Loss 15273396
esv782 CNV CNV 17122850
nsv428256 CNV Loss 18775914
nsv517440 CNV Gain+Loss 19592680
nsv437717 CNV Loss 16327808
esv22842 CNV Gain+Loss 19812545
nsv469958 CNV Loss 18288195
dgv382e1 CNV Complex 17122850
dgv50e55 CNV Loss 17911159
dgv13n68 CNV Loss 17160897
dgv212e199 CNV Deletion 23128226
dgv12n64 CNV Loss 17921354
dgv383e1 CNV Complex 17122850
dgv51e55 CNV Loss 17911159
nsv469885 CNV Loss 16826518
dgv150n27 CNV Loss 19166990
nsv442618 CNV CNV 18776908
essv101806 CNV Loss 18971310
nsv468566 CNV Loss 19166990

Variation tolerance for OR5D13 Gene

Residual Variation Intolerance Score: 71.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.01; 74.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR5D13 Gene

HapMap Linkage Disequilibrium report
OR5D13

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5D13 Gene

Disorders for OR5D13 Gene

Relevant External Links for OR5D13

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR5D13

No disorders were found for OR5D13 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5D13 Gene

Publications for OR5D13 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3
  3. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3

Products for OR5D13 Gene

Sources for OR5D13 Gene

Back to Top

Content