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Aliases for OR5B3 Gene

Aliases for OR5B3 Gene

  • Olfactory Receptor, Family 5, Subfamily B, Member 3 2 3
  • Olfactory Receptor OR11-239 3 4
  • Olfactory Receptor 5B13 3 4
  • OR5B13 3 4
  • Olfactory Receptor, Family 5, Subfamily B, Member 13 3
  • Olfactory Receptor 5B3 3
  • OR11-239 3
  • OST129 3

External Ids for OR5B3 Gene

Previous HGNC Symbols for OR5B3 Gene

  • OR5B13

Previous GeneCards Identifiers for OR5B3 Gene

  • GC00U990607
  • GC11U900574
  • GC11M057926
  • GC11M058169

Summaries for OR5B3 Gene

Entrez Gene Summary for OR5B3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5B3 Gene

OR5B3 (Olfactory Receptor, Family 5, Subfamily B, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR8H2.

UniProtKB/Swiss-Prot for OR5B3 Gene

  • Odorant receptor.

Gene Wiki entry for OR5B3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5B3 Gene

Genomics for OR5B3 Gene

Regulatory Elements for OR5B3 Gene

Genomic Location for OR5B3 Gene

Start:
58,402,464 bp from pter
End:
58,403,409 bp from pter
Size:
946 bases
Orientation:
Minus strand

Genomic View for OR5B3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5B3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5B3 Gene

Proteins for OR5B3 Gene

  • Protein details for OR5B3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH48-OR5B3_HUMAN
    Recommended name:
    Olfactory receptor 5B3
    Protein Accession:
    Q8NH48
    Secondary Accessions:
    • Q6IEV6

    Protein attributes for OR5B3 Gene

    Size:
    314 amino acids
    Molecular mass:
    35258 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5B3 Gene

Proteomics data for OR5B3 Gene at MOPED

Post-translational modifications for OR5B3 Gene

  • Glycosylation at Asn3, Asn17, and Asn153
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5B3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5B3 Gene

Domains for OR5B3 Gene

Gene Families for OR5B3 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5B3 Gene

Suggested Antigen Peptide Sequences for OR5B3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH48

UniProtKB/Swiss-Prot:

OR5B3_HUMAN :
  • Q8NH48
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5B3: view

Function for OR5B3 Gene

Molecular function for OR5B3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5B3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5B3 Gene

Localization for OR5B3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5B3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5B3 Gene COMPARTMENTS Subcellular localization image for OR5B3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR5B3: view

Pathways for OR5B3 Gene

genes like me logo Genes that share pathways with OR5B3: view

Pathways by source for OR5B3 Gene

Interacting Proteins for OR5B3 Gene

Gene Ontology (GO) - Biological Process for OR5B3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5B3: view

Transcripts for OR5B3 Gene

mRNA/cDNA for OR5B3 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR5B3

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR5B3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5B3 Gene

No ASD Table

Relevant External Links for OR5B3 Gene

GeneLoc Exon Structure for
OR5B3
ECgene alternative splicing isoforms for
OR5B3

Expression for OR5B3 Gene

mRNA expression in normal human tissues for OR5B3 Gene

SOURCE GeneReport for Unigene cluster for OR5B3 Gene Hs.553826

genes like me logo Genes that share expressions with OR5B3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR5B3 Gene

Orthologs for OR5B3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5B3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC748371 35
  • 97.98 (n)
  • 95.22 (a)
cow
(Bos Taurus)
Mammalia LOC526857 35
  • 78.95 (n)
  • 73.36 (a)
OR5B3 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 80 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
LOC483470 35
  • 84.35 (n)
  • 80.71 (a)
mouse
(Mus musculus)
Mammalia Olfr1446 36
  • 69 (a)
OneToMany
Olfr1447 36
  • 70 (a)
OneToMany
Olfr1453 36
  • 72 (a)
OneToMany
Olfr1454 36
  • 73 (a)
OneToMany
Olfr1457 16
Olfr1457 36
  • 75 (a)
OneToMany
Olfr1458 36
  • 75 (a)
OneToMany
Olfr1459 36
  • 73 (a)
OneToMany
Olfr1461 36
  • 72 (a)
OneToMany
Olfr1462 36
  • 71 (a)
OneToMany
Olfr1463 35
  • 76.55 (n)
  • 73.62 (a)
Olfr1463 36
  • 73 (a)
OneToMany
Olfr1465 36
  • 77 (a)
OneToMany
Olfr1466 36
  • 74 (a)
OneToMany
Olfr1467 36
  • 78 (a)
OneToMany
Olfr1469 36
  • 81 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 66 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
-- 36
  • 67 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
-- 36
  • 64 (a)
ManyToMany
-- 36
  • 70 (a)
ManyToMany
-- 36
  • 69 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
-- 36
  • 65 (a)
ManyToMany
-- 36
  • 64 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 55 (a)
ManyToMany
-- 36
  • 64 (a)
ManyToMany
-- 36
  • 68 (a)
ManyToMany
-- 36
  • 75 (a)
ManyToMany
-- 36
  • 71 (a)
ManyToMany
-- 36
  • 68 (a)
ManyToMany
-- 36
  • 68 (a)
ManyToMany
-- 36
  • 69 (a)
ManyToMany
-- 36
  • 71 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC687088 35
  • 79.76 (n)
  • 79.21 (a)
Species with no ortholog for OR5B3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5B3 Gene

ENSEMBL:
Gene Tree for OR5B3 (if available)
TreeFam:
Gene Tree for OR5B3 (if available)

Paralogs for OR5B3 Gene

Selected SIMAP similar genes for OR5B3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR5B3 Gene

genes like me logo Genes that share paralogs with OR5B3: view

Variants for OR5B3 Gene

Sequence variations from dbSNP and Humsavar for OR5B3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs7931126 -- 58,402,064(+) accat(C/G)aGAAC downstream-variant-500B
rs10896770 -- 58,404,863(+) TGTTT(A/T)GGAAC upstream-variant-2KB
rs10896771 -- 58,404,962(+) GAATA(G/T)GCATG upstream-variant-2KB
rs10896772 -- 58,404,979(+) AGGTT(C/T)GGAGT upstream-variant-2KB
rs10896773 -- 58,405,207(+) TCCAC(A/G)TTGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR5B3 Gene

Variant ID Type Subtype PubMed ID
nsv517849 CNV Gain 19592680

Relevant External Links for OR5B3 Gene

HapMap Linkage Disequilibrium report
OR5B3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5B3 Gene

Disorders for OR5B3 Gene

No disorders were found for OR5B3 Gene.

No data available for UniProtKB/Swiss-Prot for OR5B3 Gene

Publications for OR5B3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4

Products for OR5B3 Gene

Sources for OR5B3 Gene

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