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Aliases for OR5B17 Gene

Aliases for OR5B17 Gene

  • Olfactory Receptor Family 5 Subfamily B Member 17 2 3 5
  • Olfactory Receptor, Family 5, Subfamily B, Member 17 2 3
  • Olfactory Receptor OR11-237 3 4
  • Olfactory Receptor 5B20 3 4
  • OR5B20P 3 4
  • Olfactory Receptor, Family 5, Subfamily B, Member 20 Pseudogene 3
  • OR11-237 3

External Ids for OR5B17 Gene

Previous HGNC Symbols for OR5B17 Gene

  • OR5B20P

Previous GeneCards Identifiers for OR5B17 Gene

  • GC11U990447
  • GC11M057902
  • GC11M057882
  • GC11M058125

Summaries for OR5B17 Gene

Entrez Gene Summary for OR5B17 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5B17 Gene

OR5B17 (Olfactory Receptor Family 5 Subfamily B Member 17) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR5B12.

UniProtKB/Swiss-Prot for OR5B17 Gene

  • Odorant receptor.

Gene Wiki entry for OR5B17 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5B17 Gene

Genomics for OR5B17 Gene

Regulatory Elements for OR5B17 Gene

Enhancers for OR5B17 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR5B17 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5B17 Gene

Chromosome:
11
Start:
58,358,124 bp from pter
End:
58,359,069 bp from pter
Size:
946 bases
Orientation:
Minus strand

Genomic View for OR5B17 Gene

Genes around OR5B17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5B17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5B17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5B17 Gene

Proteins for OR5B17 Gene

  • Protein details for OR5B17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGF7-OR5BH_HUMAN
    Recommended name:
    Olfactory receptor 5B17
    Protein Accession:
    Q8NGF7
    Secondary Accessions:
    • Q6IEX1

    Protein attributes for OR5B17 Gene

    Size:
    314 amino acids
    Molecular mass:
    35091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5B17 Gene

Proteomics data for OR5B17 Gene at MOPED

Post-translational modifications for OR5B17 Gene

  • Glycosylation at Asn 3
  • Modification sites at PhosphoSitePlus

Other Protein References for OR5B17 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5B17 Gene

Domains & Families for OR5B17 Gene

Gene Families for OR5B17 Gene

Protein Domains for OR5B17 Gene

Suggested Antigen Peptide Sequences for OR5B17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGF7

UniProtKB/Swiss-Prot:

OR5BH_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5B17: view

Function for OR5B17 Gene

Molecular function for OR5B17 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5B17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5B17: view
genes like me logo Genes that share phenotypes with OR5B17: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5B17 Gene

Localization for OR5B17 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5B17 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR5B17 Gene COMPARTMENTS Subcellular localization image for OR5B17 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5B17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5B17: view

Pathways & Interactions for OR5B17 Gene

genes like me logo Genes that share pathways with OR5B17: view

Pathways by source for OR5B17 Gene

Interacting Proteins for OR5B17 Gene

Gene Ontology (GO) - Biological Process for OR5B17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5B17: view

No data available for SIGNOR curated interactions for OR5B17 Gene

Drugs & Compounds for OR5B17 Gene

No Compound Related Data Available

Transcripts for OR5B17 Gene

mRNA/cDNA for OR5B17 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5B17 Gene

No ASD Table

Relevant External Links for OR5B17 Gene

GeneLoc Exon Structure for
OR5B17
ECgene alternative splicing isoforms for
OR5B17

Expression for OR5B17 Gene

mRNA expression in normal human tissues for OR5B17 Gene

SOURCE GeneReport for Unigene cluster for OR5B17 Gene Hs.554517

genes like me logo Genes that share expression patterns with OR5B17: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR5B17 Gene

Orthologs for OR5B17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5B17 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR5B17 35
  • 80.79 (n)
  • 73.57 (a)
OR5B17 36
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC483477 35
  • 79.08 (n)
  • 73.79 (a)
OR5B17 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1467 35
  • 75.91 (n)
  • 68.65 (a)
Olfr1467 16
Olfr1443 36
  • 69 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC466602 35
  • 98.94 (n)
  • 97.13 (a)
OR5B17 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC687092 35
  • 73.62 (n)
  • 68.08 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 61 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
-- 36
  • 60 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 61 (a)
ManyToMany
-- 36
  • 64 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 61 (a)
ManyToMany
-- 36
  • 62 (a)
ManyToMany
-- 36
  • 63 (a)
ManyToMany
-- 36
  • 66 (a)
ManyToMany
-- 36
  • 58 (a)
ManyToMany
Species with no ortholog for OR5B17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5B17 Gene

ENSEMBL:
Gene Tree for OR5B17 (if available)
TreeFam:
Gene Tree for OR5B17 (if available)

Paralogs for OR5B17 Gene

Paralogs for OR5B17 Gene

(457) SIMAP similar genes for OR5B17 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5B17: view

Variants for OR5B17 Gene

Sequence variations from dbSNP and Humsavar for OR5B17 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs4939208 - 58,358,832(+) AGTTA(A/T)AACCT reference, missense
rs4127353 - 58,358,147(+) GAGAA(C/T)ATTTT reference, missense
rs1938669 -- 58,357,843(+) AATAC(A/C)TAAAA downstream-variant-500B
rs1938670 -- 58,360,170(+) CTGAA(A/G)GTGTG upstream-variant-2KB
rs1938671 -- 58,360,306(+) AGCCA(A/T)CTAGC upstream-variant-2KB

Variation tolerance for OR5B17 Gene

Residual Variation Intolerance Score: 91.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.47; 55.03% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for OR5B17 Gene

Disorders for OR5B17 Gene

Relevant External Links for OR5B17

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR5B17

No disorders were found for OR5B17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5B17 Gene

Publications for OR5B17 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67

Products for OR5B17 Gene

Sources for OR5B17 Gene

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