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Aliases for OR5AN1 Gene

Aliases for OR5AN1 Gene

  • Olfactory Receptor Family 5 Subfamily AN Member 1 2 3 5
  • Olfactory Receptor OR11-244 3 4
  • Olfactory Receptor, Family 5, Subfamily AN, Member 1 2
  • Olfactory Receptor 5AN1 3
  • Muscone Receptor 3
  • OR11-244 3

External Ids for OR5AN1 Gene

Previous GeneCards Identifiers for OR5AN1 Gene

  • GC11U990459
  • GC11P058908
  • GC11P058888
  • GC11P059131

Summaries for OR5AN1 Gene

Entrez Gene Summary for OR5AN1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5AN1 Gene

OR5AN1 (Olfactory Receptor Family 5 Subfamily AN Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR5A2.

UniProtKB/Swiss-Prot for OR5AN1 Gene

  • Odorant receptor involved in the detection of muscone.

Gene Wiki entry for OR5AN1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5AN1 Gene

Genomics for OR5AN1 Gene

Regulatory Elements for OR5AN1 Gene

Enhancers for OR5AN1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F059289 1.4 FANTOM5 Ensembl 10.5 -75.2 -75161 1.7 SPI1 OR5A2 GLYATL1 OR5AN1 OR4D6 OSBP DTX4 SLC25A47P1 LOC643709
GH11F059288 0.2 Ensembl 10.3 -76.3 -76312 0.2 MAFG NFE2 OR5A2 OR5AN1 OR4D6 SLC25A47P1 LOC643709
GH11F059283 0.5 Ensembl ENCODE 10.1 -80.1 -80112 2.2 CTCF WRNIP1 IRF3 ASH2L BMI1 EBF1 RAD21 YY1 EED ZNF143 OR5A2 OR5AN1 FAM111A ENSG00000214797 SLC25A47P1
GH11F059201 0.6 ENCODE 9.5 -162.8 -162830 0.2 CTCF NR2F1 TAL1 ZBTB11 SMC3 RAD21 GABPA OR5A2 OR5AN1 DTX4 GC11M058947
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR5AN1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR5AN1 Gene

59,364,412 bp from pter
59,365,448 bp from pter
1,037 bases
Plus strand

Genomic View for OR5AN1 Gene

Genes around OR5AN1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR5AN1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR5AN1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5AN1 Gene

Proteins for OR5AN1 Gene

  • Protein details for OR5AN1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 5AN1
    Protein Accession:
    Secondary Accessions:
    • B9EIS2
    • Q6IEV4

    Protein attributes for OR5AN1 Gene

    311 amino acids
    Molecular mass:
    34789 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5AN1 Gene

Post-translational modifications for OR5AN1 Gene

Other Protein References for OR5AN1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR5AN1 Gene

Domains & Families for OR5AN1 Gene

Gene Families for OR5AN1 Gene

Protein Domains for OR5AN1 Gene

Suggested Antigen Peptide Sequences for OR5AN1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR5AN1: view

Function for OR5AN1 Gene

Molecular function for OR5AN1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor involved in the detection of muscone.

Gene Ontology (GO) - Molecular Function for OR5AN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR5AN1: view

Phenotypes for OR5AN1 Gene

GenomeRNAi human phenotypes for OR5AN1:
genes like me logo Genes that share phenotypes with OR5AN1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR5AN1 Gene

Localization for OR5AN1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5AN1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR5AN1 Gene COMPARTMENTS Subcellular localization image for OR5AN1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR5AN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5AN1: view

Pathways & Interactions for OR5AN1 Gene

genes like me logo Genes that share pathways with OR5AN1: view

Pathways by source for OR5AN1 Gene

Gene Ontology (GO) - Biological Process for OR5AN1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5AN1: view

No data available for SIGNOR curated interactions for OR5AN1 Gene

Transcripts for OR5AN1 Gene

mRNA/cDNA for OR5AN1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR5AN1 Gene

No ASD Table

Relevant External Links for OR5AN1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR5AN1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR5AN1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR5AN1 Gene:


SOURCE GeneReport for Unigene cluster for OR5AN1 Gene:

genes like me logo Genes that share expression patterns with OR5AN1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR5AN1 Gene

Orthologs for OR5AN1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5AN1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OR5AN1 35
  • 100 (a)
LOC466609 34
  • 99.67 (n)
(Canis familiaris)
Mammalia OR04E07 34
  • 84.74 (n)
-- 35
  • 83 (a)
-- 35
  • 83 (a)
-- 35
  • 82 (a)
(Bos Taurus)
Mammalia LOC100299686 34
  • 83.28 (n)
-- 35
  • 80 (a)
-- 35
  • 79 (a)
-- 35
  • 78 (a)
-- 35
  • 77 (a)
(Mus musculus)
Mammalia Or5an1c 55 Olfr262 35
  • 81 (a)
Or5an1 55 Olfr1433 34 35
  • 80.81 (n)
Or5an1b 55 Olfr1437 35
  • 80 (a)
Or5an9 55 Olfr1431 35
  • 79 (a)
Or5an11 55 Olfr235 35
  • 79 (a)
Or5an10 55 Olfr1436 35
  • 78 (a)
Olfr1434 16
Or5an8-ps 55 Olfr1430-ps1
  • chr19:12,177,610-12,178,523
Or5q1-ps 55 Olfr1439-ps1
  • chr19:12,340,440-12,341,124
(Rattus norvegicus)
Mammalia Olr330 34
  • 80.49 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 52 (a)
Species where no ortholog for OR5AN1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5AN1 Gene

Gene Tree for OR5AN1 (if available)
Gene Tree for OR5AN1 (if available)

Paralogs for OR5AN1 Gene

Paralogs for OR5AN1 Gene

(449) SIMAP similar genes for OR5AN1 Gene using alignment to 1 proteins: Pseudogenes for OR5AN1 Gene

genes like me logo Genes that share paralogs with OR5AN1: view

Variants for OR5AN1 Gene

Sequence variations from dbSNP and Humsavar for OR5AN1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10896964 -- 59,365,409(+) TTCTG(A/G)GATTT downstream-variant-500B
rs111359240 -- 59,364,465(+) TGACT(-/G)GGGGA reference, frameshift-variant
rs111726902 -- 59,364,713(+) TCCAA(C/T)CTCTT reference, synonymous-codon
rs112933266 -- 59,363,972(+) TGGCC(A/G)GGCTG upstream-variant-2KB
rs113313120 -- 59,365,582(+) CAGGA(A/T)CTTTA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR5AN1 Gene

Variant ID Type Subtype PubMed ID
nsv1050013 CNV gain 25217958

Variation tolerance for OR5AN1 Gene

Residual Variation Intolerance Score: 70.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.73; 32.82% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR5AN1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR5AN1 Gene

Disorders for OR5AN1 Gene

Relevant External Links for OR5AN1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR5AN1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR5AN1 Gene

Publications for OR5AN1 Gene

  1. Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors. (PMID: 24361078) Shirasu M. … Touhara K. (Neuron 2014) 3 4 64
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR5AN1 Gene

Sources for OR5AN1 Gene

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