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Aliases for OR5AC1 Gene

Aliases for OR5AC1 Gene

  • Olfactory Receptor, Family 5, Subfamily AC, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor, Family 5, Subfamily AC, Member 1 Pseudogene 2 3
  • OR5AC1P 3 4
  • Olfactory Receptor OR3-2 4
  • Olfactory Receptor 5AC1 3

External Ids for OR5AC1 Gene

Previous Symbols for OR5AC1 Gene

  • OR5AC1P

Summaries for OR5AC1 Gene

Entrez Gene Summary for OR5AC1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR5AC1 Gene

OR5AC1 (Olfactory Receptor, Family 5, Subfamily AC, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR5H14.

UniProtKB/Swiss-Prot for OR5AC1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR5AC1 Gene

Genomics for OR5AC1 Gene

Genomic Location for OR5AC1 Gene

Start:
98,064,471 bp from pter
End:
98,065,396 bp from pter
Size:
926 bases
Orientation:
Plus strand

Genomic View for OR5AC1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR5AC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR5AC1 Gene

No data available for Regulatory Elements for OR5AC1 Gene

Proteins for OR5AC1 Gene

  • Protein details for OR5AC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C628-O5AC1_HUMAN
    Recommended name:
    Olfactory receptor 5AC1
    Protein Accession:
    P0C628
    Secondary Accessions:

    Protein attributes for OR5AC1 Gene

    Size:
    307 amino acids
    Molecular mass:
    34762 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR5AC1 Gene

Proteomics data for OR5AC1 Gene at MOPED

Post-translational modifications for OR5AC1 Gene

No Post-translational modifications

Other Protein References for OR5AC1 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for OR5AC1 Gene

Domains for OR5AC1 Gene

Gene Families for OR5AC1 Gene

HGNC:
  • OR5 :GPCR / Class A : Olfactory receptors

Protein Domains for OR5AC1 Gene

UniProtKB/Swiss-Prot:

O5AC1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • P0C628
genes like me logo Genes that share domains with OR5AC1: view

Function for OR5AC1 Gene

Molecular function for OR5AC1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR5AC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR5AC1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR5AC1 Gene

Localization for OR5AC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR5AC1 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR5AC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR5AC1: view

Pathways for OR5AC1 Gene

genes like me logo Genes that share pathways with OR5AC1: view

Pathways by source for OR5AC1 Gene

Interacting Proteins for OR5AC1 Gene

Gene Ontology (GO) - Biological Process for OR5AC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR5AC1: view

Transcripts for OR5AC1 Gene

mRNA/cDNA for OR5AC1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR5AC1 Gene

No ASD Table

Relevant External Links for OR5AC1 Gene

GeneLoc Exon Structure for
OR5AC1
ECgene alternative splicing isoforms for
OR5AC1

Expression for OR5AC1 Gene

mRNA expression in normal human tissues for OR5AC1 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OR5AC1 Gene

genes like me logo Genes that share expressions with OR5AC1: view

Orthologs for OR5AC1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR5AC1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 37
  • 35 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 31 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr199 37
  • 33 (a)
ManyToMany
Olfr201 37
  • 33 (a)
ManyToMany
Olfr202 37
  • 35 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 32 (a)
ManyToMany
-- 37
  • 33 (a)
ManyToMany
-- 37
  • 32 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 34 (a)
ManyToMany
Species with no ortholog for OR5AC1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR5AC1 Gene

ENSEMBL:
Gene Tree for OR5AC1 (if available)
TreeFam:
Gene Tree for OR5AC1 (if available)

Paralogs for OR5AC1 Gene

Paralogs for OR5AC1 Gene

Selected SIMAP similar genes for OR5AC1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR5AC1: view

Variants for OR5AC1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR5AC1 Gene

P0C628-O5AC1_HUMAN
A single nucleotide deletion at position Phe-85 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene

Relevant External Links for OR5AC1 Gene

HapMap Linkage Disequilibrium report
OR5AC1

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for OR5AC1 Gene

Disorders for OR5AC1 Gene

No disorders were found for OR5AC1 Gene.

No data available for UniProtKB/Swiss-Prot for OR5AC1 Gene

Publications for OR5AC1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Genetic elucidation of human hyperosmia to isovaleric acid. (PMID: 17973576) Menashe I. … Lancet D. (PLoS Biol. 2007) 3 4

Products for OR5AC1 Gene

Sources for OR5AC1 Gene

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