Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR56A5 Gene

Aliases for OR56A5 Gene

  • Olfactory Receptor Family 56 Subfamily A Member 5 2 3 5
  • OR56A5P 3 4
  • Olfactory Receptor, Family 56, Subfamily A, Member 5 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 5 2
  • Olfactory Receptor 56A5 3

External Ids for OR56A5 Gene

Previous HGNC Symbols for OR56A5 Gene

  • OR56A5P

Previous GeneCards Identifiers for OR56A5 Gene

  • GC11U900569
  • GC11M005946
  • GC11M005949

Summaries for OR56A5 Gene

Entrez Gene Summary for OR56A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Mar 2009]

GeneCards Summary for OR56A5 Gene

OR56A5 (Olfactory Receptor Family 56 Subfamily A Member 5) is a Protein Coding gene. Among its related pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56A4.

UniProtKB/Swiss-Prot for OR56A5 Gene

  • Odorant receptor.

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A5 Gene

Genomics for OR56A5 Gene

Regulatory Elements for OR56A5 Gene

Enhancers for OR56A5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G005546 0.3 FANTOM5 8.7 +422.2 422249 0.1 OR56A1 OR56A3 OR51Q1 OR52E8 OR52N1 OR56A4 OR52N4 OR52E2 OR52E4 OR52A1
GH11G006094 0.4 FANTOM5 1.4 -125.9 -125926 0.1 GATA2 OR56A1 OR52W1 FAM160A2 C11orf42 TRIM5 TRIM34 OR52N1 OR56A3 OR52E8 TRIM22
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR56A5 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR56A5 Gene

Chromosome:
11
Start:
5,967,177 bp from pter
End:
5,968,494 bp from pter
Size:
1,318 bases
Orientation:
Minus strand

Genomic View for OR56A5 Gene

Genes around OR56A5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56A5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A5 Gene

Proteins for OR56A5 Gene

  • Protein details for OR56A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7T3-O56A5_HUMAN
    Recommended name:
    Olfactory receptor 56A5
    Protein Accession:
    P0C7T3

    Protein attributes for OR56A5 Gene

    Size:
    313 amino acids
    Molecular mass:
    35317 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR56A5 Gene

Post-translational modifications for OR56A5 Gene

  • Glycosylation at posLast=66, posLast=77, Asn184, and posLast=198198

Other Protein References for OR56A5 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56A5 Gene

Domains & Families for OR56A5 Gene

Gene Families for OR56A5 Gene

Protein Domains for OR56A5 Gene

Suggested Antigen Peptide Sequences for OR56A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7T3

UniProtKB/Swiss-Prot:

O56A5_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56A5: view

Function for OR56A5 Gene

Molecular function for OR56A5 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IBA --
GO:0004871 signal transducer activity IEA --
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004935 NOT adrenergic receptor activity IBA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56A5: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56A5 Gene

Localization for OR56A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A5 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0030672 synaptic vesicle membrane IBA --
genes like me logo Genes that share ontologies with OR56A5: view

No data available for Subcellular locations from COMPARTMENTS for OR56A5 Gene

Pathways & Interactions for OR56A5 Gene

genes like me logo Genes that share pathways with OR56A5: view

Pathways by source for OR56A5 Gene

Interacting Proteins for OR56A5 Gene

Gene Ontology (GO) - Biological Process for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001963 synaptic transmission, dopaminergic IBA --
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007194 negative regulation of adenylate cyclase activity IBA --
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with OR56A5: view

No data available for SIGNOR curated interactions for OR56A5 Gene

Drugs & Compounds for OR56A5 Gene

No Compound Related Data Available

Transcripts for OR56A5 Gene

mRNA/cDNA for OR56A5 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A5 Gene

ExUns: 1a · 1b ^ 2
SP1:
SP2:

Relevant External Links for OR56A5 Gene

GeneLoc Exon Structure for
OR56A5
ECgene alternative splicing isoforms for
OR56A5

Expression for OR56A5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR56A5 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR56A5 Gene:

OR56A5

SOURCE GeneReport for Unigene cluster for OR56A5 Gene:

Hs.719888
genes like me logo Genes that share expression patterns with OR56A5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR56A5 Gene

Orthologs for OR56A5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR56A5 34
  • 99.47 (n)
dog
(Canis familiaris)
Mammalia cOR56A24 34
  • 88.18 (n)
cow
(Bos Taurus)
Mammalia OR56A4 34
  • 85.73 (n)
mouse
(Mus musculus)
Mammalia Or56a5 55 Olfr683 34 16
  • 85.42 (n)
rat
(Rattus norvegicus)
Mammalia Olr192 34
  • 84.46 (n)
Species where no ortholog for OR56A5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A5 Gene

ENSEMBL:
Gene Tree for OR56A5 (if available)
TreeFam:
Gene Tree for OR56A5 (if available)

Paralogs for OR56A5 Gene

Paralogs for OR56A5 Gene

(429) SIMAP similar genes for OR56A5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR56A5: view

Variants for OR56A5 Gene

Sequence variations from dbSNP and Humsavar for OR56A5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000610464 -- 5,967,838(+) TAAGA(A/G)AGAAC reference, synonymous-codon
rs1000961430 -- 5,967,467(+) GCAGT(A/G)ACAAT downstream-variant-500B
rs1001839470 -- 5,968,620(+) TGAGA(C/T)ACAGA upstream-variant-2KB
rs1003500856 -- 5,969,500(+) CTCTA(C/T)CCCTT upstream-variant-2KB
rs1003846448 -- 5,969,878(+) ATGAG(A/T)AAAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR56A5 Gene

Variant ID Type Subtype PubMed ID
esv2759801 CNV gain+loss 17122850
nsv1046068 CNV gain 25217958
nsv1053414 CNV gain 25217958
nsv553241 CNV gain 21841781
nsv553277 CNV gain 21841781
nsv975875 CNV duplication 23825009

Relevant External Links for OR56A5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR56A5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR56A5 Gene

Disorders for OR56A5 Gene

Relevant External Links for OR56A5

Genetic Association Database (GAD)
OR56A5
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR56A5

No disorders were found for OR56A5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR56A5 Gene

Publications for OR56A5 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4 64

Products for OR56A5 Gene

Sources for OR56A5 Gene

Content
Loading form....