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Aliases for OR56A5 Gene

Aliases for OR56A5 Gene

  • Olfactory Receptor, Family 56, Subfamily A, Member 5 2 3
  • OR56A5P 3 4
  • Olfactory Receptor, Family 56, Subfamily A, Member 5 Pseudogene 3
  • Olfactory Receptor 56A5 3

External Ids for OR56A5 Gene

Previous HGNC Symbols for OR56A5 Gene

  • OR56A5P

Previous GeneCards Identifiers for OR56A5 Gene

  • GC11U900569
  • GC11M005946
  • GC11M005949

Summaries for OR56A5 Gene

Entrez Gene Summary for OR56A5 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Mar 2009]

GeneCards Summary for OR56A5 Gene

OR56A5 (Olfactory Receptor, Family 56, Subfamily A, Member 5) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and adrenergic receptor activity.

UniProtKB/Swiss-Prot for OR56A5 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A5 Gene

Genomics for OR56A5 Gene

Regulatory Elements for OR56A5 Gene

Genomic Location for OR56A5 Gene

Start:
5,967,177 bp from pter
End:
5,968,494 bp from pter
Size:
1,318 bases
Orientation:
Minus strand

Genomic View for OR56A5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR56A5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A5 Gene

Proteins for OR56A5 Gene

  • Protein details for OR56A5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7T3-O56A5_HUMAN
    Recommended name:
    Olfactory receptor 56A5
    Protein Accession:
    P0C7T3
    Secondary Accessions:

    Protein attributes for OR56A5 Gene

    Size:
    313 amino acids
    Molecular mass:
    35317 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR56A5 Gene

Proteomics data for OR56A5 Gene at MOPED

Post-translational modifications for OR56A5 Gene

  • Glycosylation at Asn6, Asn7, Asn184, and Asn198

Other Protein References for OR56A5 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56A5 Gene

Domains for OR56A5 Gene

Gene Families for OR56A5 Gene

HGNC:
  • OR56 :GPCR / Class A : Olfactory receptors

Protein Domains for OR56A5 Gene

Suggested Antigen Peptide Sequences for OR56A5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7T3

UniProtKB/Swiss-Prot:

O56A5_HUMAN :
  • P0C7T3
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56A5: view

Function for OR56A5 Gene

Molecular function for OR56A5 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56A5: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR56A5

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR56A5 Gene

Localization for OR56A5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A5 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR56A5 Gene COMPARTMENTS Subcellular localization image for OR56A5 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56A5: view

Pathways for OR56A5 Gene

genes like me logo Genes that share pathways with OR56A5: view

Pathways by source for OR56A5 Gene

Interacting Proteins for OR56A5 Gene

Gene Ontology (GO) - Biological Process for OR56A5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56A5: view

Transcripts for OR56A5 Gene

mRNA/cDNA for OR56A5 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR56A5

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A5 Gene

ExUns: 1a · 1b ^ 2
SP1:
SP2:

Relevant External Links for OR56A5 Gene

GeneLoc Exon Structure for
OR56A5
ECgene alternative splicing isoforms for
OR56A5

Expression for OR56A5 Gene

mRNA expression in normal human tissues for OR56A5 Gene

SOURCE GeneReport for Unigene cluster for OR56A5 Gene Hs.719888

genes like me logo Genes that share expressions with OR56A5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR56A5 Gene

Orthologs for OR56A5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OR56A5 35
  • 99.47 (n)
  • 99.68 (a)
cow
(Bos Taurus)
Mammalia OR56A4 35
  • 85.73 (n)
  • 84.35 (a)
dog
(Canis familiaris)
Mammalia cOR56A24 35
  • 88.18 (n)
  • 89.46 (a)
mouse
(Mus musculus)
Mammalia Olfr683 35
  • 85.42 (n)
  • 84.89 (a)
Olfr683 16
rat
(Rattus norvegicus)
Mammalia Olr192 35
  • 84.46 (n)
  • 84.89 (a)
Species with no ortholog for OR56A5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A5 Gene

ENSEMBL:
Gene Tree for OR56A5 (if available)
TreeFam:
Gene Tree for OR56A5 (if available)

Paralogs for OR56A5 Gene

Selected SIMAP similar genes for OR56A5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR56A5: view

No data available for Paralogs for OR56A5 Gene

Variants for OR56A5 Gene

Sequence variations from dbSNP and Humsavar for OR56A5 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs4237764 -- 5,969,863(+) TAAAT(A/G)GCTCT upstream-variant-2KB
rs4237765 -- 5,969,891(+) GCATA(A/T)TTTAG upstream-variant-2KB
rs4758275 -- 5,967,110(+) GTCCA(C/T)AAGAG downstream-variant-500B
rs4758276 -- 5,967,216(+) GGAAT(C/T)GAGAA downstream-variant-500B
rs5789430 -- 5,969,932(+) CAGTG(-/ATT/G/T/TTA)AGACT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR56A5 Gene

Variant ID Type Subtype PubMed ID
dgv345e1 CNV Complex 17122850

Relevant External Links for OR56A5 Gene

HapMap Linkage Disequilibrium report
OR56A5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR56A5 Gene

Disorders for OR56A5 Gene

Relevant External Links for OR56A5

Genetic Association Database (GAD)
OR56A5
genes like me logo Genes that share disorders with OR56A5: view

No data available for UniProtKB/Swiss-Prot for OR56A5 Gene

Publications for OR56A5 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4

Products for OR56A5 Gene

Sources for OR56A5 Gene

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