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Aliases for OR56A4 Gene

Aliases for OR56A4 Gene

  • Olfactory Receptor, Family 56, Subfamily A, Member 4 2 3
  • Olfactory Receptor OR11-49 3 4
  • Olfactory Receptor 56A4 3
  • OR11-49 3

External Ids for OR56A4 Gene

Summaries for OR56A4 Gene

Entrez Gene Summary for OR56A4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56A4 Gene

OR56A4 (Olfactory Receptor, Family 56, Subfamily A, Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include olfactory receptor activity and adrenergic receptor activity. An important paralog of this gene is OR56B1.

UniProtKB/Swiss-Prot for OR56A4 Gene

  • Odorant receptor.

Gene Wiki entry for OR56A4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A4 Gene

Genomics for OR56A4 Gene

Genomic Location for OR56A4 Gene

Start:
6,001,986 bp from pter
End:
6,003,194 bp from pter
Size:
1,209 bases
Orientation:
Minus strand

Genomic View for OR56A4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR56A4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A4 Gene

Regulatory Elements for OR56A4 Gene

Proteins for OR56A4 Gene

  • Protein details for OR56A4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGH8-O56A4_HUMAN
    Recommended name:
    Olfactory receptor 56A4
    Protein Accession:
    Q8NGH8
    Secondary Accessions:
    • B9EH17

    Protein attributes for OR56A4 Gene

    Size:
    313 amino acids
    Molecular mass:
    35116 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI36987.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR56A4 Gene

Proteomics data for OR56A4 Gene at MOPED

Post-translational modifications for OR56A4 Gene

Other Protein References for OR56A4 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR56A4 Gene

Domains for OR56A4 Gene

Gene Families for OR56A4 Gene

HGNC:
  • OR56 :GPCR / Class A : Olfactory receptors

Protein Domains for OR56A4 Gene

Suggested Antigen Peptide Sequences for OR56A4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGH8

UniProtKB/Swiss-Prot:

O56A4_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGH8
genes like me logo Genes that share domains with OR56A4: view

Function for OR56A4 Gene

Molecular function for OR56A4 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56A4: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR56A4 Gene

Localization for OR56A4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR56A4 Gene COMPARTMENTS Subcellular localization image for OR56A4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56A4: view

Pathways for OR56A4 Gene

genes like me logo Genes that share pathways with OR56A4: view

Pathways by source for OR56A4 Gene

Interacting Proteins for OR56A4 Gene

Gene Ontology (GO) - Biological Process for OR56A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56A4: view

Transcripts for OR56A4 Gene

mRNA/cDNA for OR56A4 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A4 Gene

No ASD Table

Relevant External Links for OR56A4 Gene

GeneLoc Exon Structure for
OR56A4
ECgene alternative splicing isoforms for
OR56A4

Expression for OR56A4 Gene

mRNA expression in normal human tissues for OR56A4 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR56A4 Gene

SOURCE GeneReport for Unigene cluster for OR56A4 Gene Hs.553571

genes like me logo Genes that share expressions with OR56A4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR56A4 Gene

Orthologs for OR56A4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR56A4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466405 35
  • 99.18 (n)
  • 98.08 (a)
OR56A4 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 88 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
LOC100298165 35
  • 88.07 (n)
  • 87.86 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 91 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
LOC610901 35
  • 79.98 (n)
  • 81.47 (a)
mouse
(Mus musculus)
Mammalia Olfr683 36
  • 82 (a)
OneToMany
Olfr684 35
  • 83.82 (n)
  • 87.06 (a)
Olfr684 16
Olfr684 36
  • 87 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 82 (a)
OneToMany
-- 36
  • 80 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 69 (a)
ManyToMany
-- 36
  • 67 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr193 35
  • 84.4 (n)
  • 87.5 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 35
Species with no ortholog for OR56A4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR56A4 Gene

ENSEMBL:
Gene Tree for OR56A4 (if available)
TreeFam:
Gene Tree for OR56A4 (if available)

Paralogs for OR56A4 Gene

Paralogs for OR56A4 Gene

Selected SIMAP similar genes for OR56A4 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR56A4 Gene

genes like me logo Genes that share paralogs with OR56A4: view

Variants for OR56A4 Gene

Sequence variations from dbSNP and Humsavar for OR56A4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs17480 -- 6,004,881(+) AGTAC(A/G)TTGCA upstream-variant-2KB
rs4313568 -- 6,004,273(+) GAACC(A/G)GACCT upstream-variant-2KB
rs4315052 -- 6,005,096(+) TGATC(A/G)TGTAA upstream-variant-2KB
rs4758066 -- 6,001,561(+) GCACT(C/G)AACCC downstream-variant-500B
rs7926146 -- 6,004,522(+) TATTT(A/C)TTTAA upstream-variant-2KB

Relevant External Links for OR56A4 Gene

HapMap Linkage Disequilibrium report
OR56A4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR56A4 Gene

Disorders for OR56A4 Gene

No disorders were found for OR56A4 Gene.

No data available for UniProtKB/Swiss-Prot for OR56A4 Gene

Publications for OR56A4 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR56A4 Gene

Sources for OR56A4 Gene

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