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Aliases for OR56A3 Gene

Aliases for OR56A3 Gene

  • Olfactory Receptor, Family 56, Subfamily A, Member 3 2 3
  • Olfactory Receptor 56A6 3 4
  • OR56A3P 3 4
  • OR56A6 3 4
  • Olfactory Receptor, Family 56, Subfamily A, Member 2 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 6 3
  • Olfactory Receptor OR11-51 3
  • Olfactory Receptor 56A3 3
  • OR56A2P 3

External Ids for OR56A3 Gene

Previous Symbols for OR56A3 Gene

  • OR56A6
  • OR56A3P

Summaries for OR56A3 Gene

Entrez Gene Summary for OR56A3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56A3 Gene

OR56A3 (Olfactory Receptor, Family 56, Subfamily A, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56A4.

UniProtKB/Swiss-Prot for OR56A3 Gene

  • Odorant receptor.

Gene Wiki entry for OR56A3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A3 Gene

Genomics for OR56A3 Gene

Genomic Location for OR56A3 Gene

Start:
5,947,340 bp from pter
End:
5,948,361 bp from pter
Size:
1,022 bases
Orientation:
Plus strand

Genomic View for OR56A3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR56A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A3 Gene

Regulatory Elements for OR56A3 Gene

Proteins for OR56A3 Gene

  • Protein details for OR56A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH54-O56A3_HUMAN
    Recommended name:
    Olfactory receptor 56A3
    Protein Accession:
    Q8NH54
    Secondary Accessions:
    • A6NN77
    • Q6IFF7

    Protein attributes for OR56A3 Gene

    Size:
    315 amino acids
    Molecular mass:
    35611 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05783.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for OR56A3 Gene

Proteomics data for OR56A3 Gene at MOPED

Post-translational modifications for OR56A3 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn6 and Asn185

Other Protein References for OR56A3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR56A3 Gene

Domains for OR56A3 Gene

Gene Families for OR56A3 Gene

HGNC:
  • OR56 :GPCR / Class A : Olfactory receptors

Protein Domains for OR56A3 Gene

UniProtKB/Swiss-Prot:

O56A3_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NH54
genes like me logo Genes that share domains with OR56A3: view

Function for OR56A3 Gene

Molecular function for OR56A3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR56A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR56A3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR56A3 Gene

Localization for OR56A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR56A3 Gene COMPARTMENTS Subcellular localization image for OR56A3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56A3: view

Pathways for OR56A3 Gene

genes like me logo Genes that share pathways with OR56A3: view

Pathways by source for OR56A3 Gene

Interacting Proteins for OR56A3 Gene

Gene Ontology (GO) - Biological Process for OR56A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56A3: view

Transcripts for OR56A3 Gene

mRNA/cDNA for OR56A3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A3 Gene

No ASD Table

Relevant External Links for OR56A3 Gene

GeneLoc Exon Structure for
OR56A3
ECgene alternative splicing isoforms for
OR56A3

Expression for OR56A3 Gene

mRNA expression in normal human tissues for OR56A3 Gene

mRNA differential expression in normal tissues according to GTEx for OR56A3 Gene

This gene is overexpressed in Testis (30.8), Liver (10.7), Bladder (6.0), and Cervix - Endocervix (5.5).

SOURCE GeneReport for Unigene cluster for OR56A3 Gene Hs.553741

genes like me logo Genes that share expressions with OR56A3: view

Orthologs for OR56A3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466402 36
  • 99.05 (n)
  • 99.37 (a)
OR56A3 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR56A3 36
  • 87.05 (n)
  • 87.58 (a)
OR56A3 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 83 (a)
OneToMany
-- 37
  • 86 (a)
OneToMany
-- 37
  • 83 (a)
OneToMany
LOC485316 36
  • 85.99 (n)
  • 86.31 (a)
mouse
(Mus musculus)
Mammalia Olfr679 36
  • 83.55 (n)
  • 85.35 (a)
Olfr679 37
  • 85 (a)
OneToMany
Olfr681 16
Olfr681 37
  • 85 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 80 (a)
OneToMany
-- 37
  • 80 (a)
OneToMany
-- 37
  • 84 (a)
OneToMany
-- 37
  • 80 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 68 (a)
ManyToMany
-- 37
  • 67 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr190 36
  • 83.86 (n)
  • 86.62 (a)
Species with no ortholog for OR56A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A3 Gene

ENSEMBL:
Gene Tree for OR56A3 (if available)
TreeFam:
Gene Tree for OR56A3 (if available)

Paralogs for OR56A3 Gene

Paralogs for OR56A3 Gene

Selected SIMAP similar genes for OR56A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR56A3: view

Variants for OR56A3 Gene

Sequence variations from dbSNP and Humsavar for OR56A3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1453430 -- 5,946,717(-) CATAG(A/G)TTCCA upstream-variant-2KB
rs1453431 -- 5,946,517(-) CCTTT(A/G)AAGTC upstream-variant-2KB
rs1840178 - 5,947,498(-) TGGTC(A/G)TCAGG reference, missense
rs3082300 -- 5,945,580(+) AAAAA(-/A)AAATT upstream-variant-2KB
rs6578710 -- 5,945,601(+) AAAAA(A/G)AATTA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR56A3 Gene

Variant ID Type Subtype PubMed ID
dgv341e1 CNV Complex 17122850
dgv345e1 CNV Complex 17122850
dgv40e55 CNV Gain 17911159

Relevant External Links for OR56A3 Gene

HapMap Linkage Disequilibrium report
OR56A3

Disorders for OR56A3 Gene

No disorders were found for OR56A3 Gene.

No data available for UniProtKB/Swiss-Prot for OR56A3 Gene

Publications for OR56A3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR56A3 Gene

Sources for OR56A3 Gene

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