Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR56A3 Gene

Aliases for OR56A3 Gene

  • Olfactory Receptor Family 56 Subfamily A Member 3 2 3 5
  • Olfactory Receptor 56A6 3 4
  • OR56A3P 3 4
  • OR56A6 3 4
  • Olfactory Receptor, Family 56, Subfamily A, Member 2 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 3 Pseudogene 3
  • Olfactory Receptor, Family 56, Subfamily A, Member 3 2
  • Olfactory Receptor, Family 56, Subfamily A, Member 6 3
  • Olfactory Receptor OR11-51 3
  • OR56A2P 3

External Ids for OR56A3 Gene

Previous HGNC Symbols for OR56A3 Gene

  • OR56A6
  • OR56A3P

Previous GeneCards Identifiers for OR56A3 Gene

  • GC11P005933
  • GC11P005925

Summaries for OR56A3 Gene

Entrez Gene Summary for OR56A3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56A3 Gene

OR56A3 (Olfactory Receptor Family 56 Subfamily A Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56A4.

UniProtKB/Swiss-Prot for OR56A3 Gene

  • Odorant receptor.

Gene Wiki entry for OR56A3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A3 Gene

Genomics for OR56A3 Gene

Regulatory Elements for OR56A3 Gene

Enhancers for OR56A3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR56A3 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR56A3 Gene

5,947,340 bp from pter
5,948,361 bp from pter
1,022 bases
Plus strand

Genomic View for OR56A3 Gene

Genes around OR56A3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56A3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A3 Gene

Proteins for OR56A3 Gene

  • Protein details for OR56A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 56A3
    Protein Accession:
    Secondary Accessions:
    • A6NN77
    • Q6IFF7

    Protein attributes for OR56A3 Gene

    315 amino acids
    Molecular mass:
    35611 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC05783.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for OR56A3 Gene

Proteomics data for OR56A3 Gene at MOPED

Post-translational modifications for OR56A3 Gene

  • Glycosylation at Asn 6 and Asn 185
  • Modification sites at PhosphoSitePlus

Other Protein References for OR56A3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56A3 Gene

Domains & Families for OR56A3 Gene

Gene Families for OR56A3 Gene

Protein Domains for OR56A3 Gene

Suggested Antigen Peptide Sequences for OR56A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56A3: view

Function for OR56A3 Gene

Molecular function for OR56A3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR56A3 Gene

genes like me logo Genes that share phenotypes with OR56A3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56A3 Gene

Localization for OR56A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR56A3 Gene COMPARTMENTS Subcellular localization image for OR56A3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56A3: view

Pathways & Interactions for OR56A3 Gene

genes like me logo Genes that share pathways with OR56A3: view

Pathways by source for OR56A3 Gene

Interacting Proteins for OR56A3 Gene

Gene Ontology (GO) - Biological Process for OR56A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR56A3: view

No data available for SIGNOR curated interactions for OR56A3 Gene

Drugs & Compounds for OR56A3 Gene

No Compound Related Data Available

Transcripts for OR56A3 Gene

mRNA/cDNA for OR56A3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A3 Gene

No ASD Table

Relevant External Links for OR56A3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR56A3 Gene

mRNA expression in normal human tissues for OR56A3 Gene

mRNA differential expression in normal tissues according to GTEx for OR56A3 Gene

This gene is overexpressed in Testis (x30.8), Liver (x10.7), Bladder (x6.0), and Cervix - Endocervix (x5.5).

SOURCE GeneReport for Unigene cluster for OR56A3 Gene Hs.553741

genes like me logo Genes that share expression patterns with OR56A3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR56A3 Gene

Orthologs for OR56A3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR56A3 35
  • 87.05 (n)
  • 87.58 (a)
OR56A3 36
  • 87 (a)
(Canis familiaris)
Mammalia LOC485316 35
  • 85.99 (n)
  • 86.31 (a)
-- 36
  • 83 (a)
-- 36
  • 86 (a)
-- 36
  • 83 (a)
(Mus musculus)
Mammalia Olfr679 35
  • 83.55 (n)
  • 85.35 (a)
Olfr681 16
Olfr679 36
  • 85 (a)
Olfr681 36
  • 85 (a)
(Pan troglodytes)
Mammalia LOC466402 35
  • 99.05 (n)
  • 99.37 (a)
OR56A3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Olr190 35
  • 83.86 (n)
  • 86.62 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
-- 36
  • 80 (a)
-- 36
  • 84 (a)
-- 36
  • 80 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 68 (a)
-- 36
  • 67 (a)
Species with no ortholog for OR56A3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A3 Gene

Gene Tree for OR56A3 (if available)
Gene Tree for OR56A3 (if available)

Paralogs for OR56A3 Gene

Paralogs for OR56A3 Gene

(421) SIMAP similar genes for OR56A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR56A3: view

Variants for OR56A3 Gene

Sequence variations from dbSNP and Humsavar for OR56A3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1840178 - 5,947,498(-) TGGTC(A/G)TCAGG reference, missense
rs1453430 -- 5,946,717(-) CATAG(A/G)TTCCA upstream-variant-2KB
rs1453431 -- 5,946,517(-) CCTTT(A/G)AAGTC upstream-variant-2KB
rs112549328 -- 5,947,426(+) CAGCT(A/G)GCAGC reference, stop-gained
rs113017536 -- 5,946,751(+) TAGAC(A/G)AAATA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR56A3 Gene

Variant ID Type Subtype PubMed ID
dgv341e1 CNV Complex 17122850
dgv345e1 CNV Complex 17122850
dgv40e55 CNV Gain 17911159

Variation tolerance for OR56A3 Gene

Residual Variation Intolerance Score: 60.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.48; 10.50% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR56A3 Gene

Disorders for OR56A3 Gene

Relevant External Links for OR56A3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR56A3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR56A3 Gene

Publications for OR56A3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67

Products for OR56A3 Gene

Sources for OR56A3 Gene