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Aliases for OR56A1 Gene

Aliases for OR56A1 Gene

  • Olfactory Receptor Family 56 Subfamily A Member 1 2 3 5
  • Olfactory Receptor, Family 56, Subfamily A, Member 1 2 3
  • Olfactory Receptor OR11-75 3 4
  • OR11-75 3

External Ids for OR56A1 Gene

Previous GeneCards Identifiers for OR56A1 Gene

  • GC11U990305
  • GC11M006013
  • GC11M006004
  • GC11M006048

Summaries for OR56A1 Gene

Entrez Gene Summary for OR56A1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR56A1 Gene

OR56A1 (Olfactory Receptor Family 56 Subfamily A Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR56A4.

UniProtKB/Swiss-Prot for OR56A1 Gene

  • Odorant receptor.

Gene Wiki entry for OR56A1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR56A1 Gene

Genomics for OR56A1 Gene

Regulatory Elements for OR56A1 Gene

Genomic Location for OR56A1 Gene

Chromosome:
11
Start:
6,026,671 bp from pter
End:
6,027,741 bp from pter
Size:
1,071 bases
Orientation:
Minus strand

Genomic View for OR56A1 Gene

Genes around OR56A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR56A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR56A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR56A1 Gene

Proteins for OR56A1 Gene

  • Protein details for OR56A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGH5-O56A1_HUMAN
    Recommended name:
    Olfactory receptor 56A1
    Protein Accession:
    Q8NGH5
    Secondary Accessions:
    • B2RNI2
    • Q6IFL0

    Protein attributes for OR56A1 Gene

    Size:
    318 amino acids
    Molecular mass:
    35823 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR56A1 Gene

Proteomics data for OR56A1 Gene at MOPED

Post-translational modifications for OR56A1 Gene

  • Glycosylation at Asn 10, Asn 188, and Asn 198
  • Modification sites at PhosphoSitePlus

Other Protein References for OR56A1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR56A1 Gene

Domains & Families for OR56A1 Gene

Gene Families for OR56A1 Gene

Protein Domains for OR56A1 Gene

Suggested Antigen Peptide Sequences for OR56A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGH5

UniProtKB/Swiss-Prot:

O56A1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR56A1: view

Function for OR56A1 Gene

Molecular function for OR56A1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR56A1 Gene

genes like me logo Genes that share phenotypes with OR56A1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR56A1 Gene

Localization for OR56A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR56A1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR56A1 Gene COMPARTMENTS Subcellular localization image for OR56A1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR56A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR56A1: view

Pathways & Interactions for OR56A1 Gene

genes like me logo Genes that share pathways with OR56A1: view

Pathways by source for OR56A1 Gene

Interacting Proteins for OR56A1 Gene

Gene Ontology (GO) - Biological Process for OR56A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007267 cell-cell signaling IBA --
genes like me logo Genes that share ontologies with OR56A1: view

No data available for SIGNOR curated interactions for OR56A1 Gene

Drugs & Compounds for OR56A1 Gene

No Compound Related Data Available

Transcripts for OR56A1 Gene

mRNA/cDNA for OR56A1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR56A1 Gene

No ASD Table

Relevant External Links for OR56A1 Gene

GeneLoc Exon Structure for
OR56A1
ECgene alternative splicing isoforms for
OR56A1

Expression for OR56A1 Gene

mRNA expression in normal human tissues for OR56A1 Gene

mRNA differential expression in normal tissues according to GTEx for OR56A1 Gene

This gene is overexpressed in Testis (x53.0).

SOURCE GeneReport for Unigene cluster for OR56A1 Gene Hs.553543

genes like me logo Genes that share expression patterns with OR56A1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR56A1 Gene

Orthologs for OR56A1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR56A1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR56A1 35
  • 86.47 (n)
  • 84.98 (a)
OR56A1 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC485323 35
  • 88.6 (n)
  • 90.1 (a)
OR56A1 36
  • 92 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC466406 35
  • 99.48 (n)
  • 98.74 (a)
OR56A1 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 84 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr682-ps1 36
  • 68 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 72 (a)
ManyToMany
-- 36
  • 69 (a)
ManyToMany
Species with no ortholog for OR56A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR56A1 Gene

ENSEMBL:
Gene Tree for OR56A1 (if available)
TreeFam:
Gene Tree for OR56A1 (if available)

Paralogs for OR56A1 Gene

Paralogs for OR56A1 Gene

(440) SIMAP similar genes for OR56A1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR56A1 Gene

genes like me logo Genes that share paralogs with OR56A1: view

Variants for OR56A1 Gene

Sequence variations from dbSNP and Humsavar for OR56A1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs4522148 -- 6,029,735(+) CGTCA(A/G)TTTAA upstream-variant-2KB
rs7937144 -- 6,026,305(+) AAAGA(C/G)AAAAT downstream-variant-500B
rs10839266 -- 6,028,301(+) AAACT(A/G)AAAAA upstream-variant-2KB
rs11040335 -- 6,026,826(+) TTCAA(C/T)GCAGG reference, synonymous-codon
rs12364113 -- 6,028,658(+) acatg(A/T)ataag upstream-variant-2KB

Variation tolerance for OR56A1 Gene

Residual Variation Intolerance Score: 47.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.29; 40.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR56A1 Gene

HapMap Linkage Disequilibrium report
OR56A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OR56A1 Gene

Disorders for OR56A1 Gene

Relevant External Links for OR56A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR56A1

No disorders were found for OR56A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR56A1 Gene

Publications for OR56A1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR56A1 Gene

Sources for OR56A1 Gene

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