Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR52J3 Gene

Aliases for OR52J3 Gene

  • Olfactory Receptor Family 52 Subfamily J Member 3 2 3 5
  • Olfactory Receptor, Family 52, Subfamily J, Member 3 2 3
  • Olfactory Receptor OR11-32 3 4
  • OR11-32 3

External Ids for OR52J3 Gene

Previous GeneCards Identifiers for OR52J3 Gene

  • GC11U990367
  • GC11P005034

Summaries for OR52J3 Gene

Entrez Gene Summary for OR52J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR52J3 Gene

OR52J3 (Olfactory Receptor Family 52 Subfamily J Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR52D1.

UniProtKB/Swiss-Prot for OR52J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR52J3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR52J3 Gene

Genomics for OR52J3 Gene

Regulatory Elements for OR52J3 Gene

Genomic Location for OR52J3 Gene

Chromosome:
11
Start:
5,046,526 bp from pter
End:
5,047,461 bp from pter
Size:
936 bases
Orientation:
Plus strand

Genomic View for OR52J3 Gene

Genes around OR52J3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR52J3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR52J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR52J3 Gene

Proteins for OR52J3 Gene

  • Protein details for OR52J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH60-O52J3_HUMAN
    Recommended name:
    Olfactory receptor 52J3
    Protein Accession:
    Q8NH60
    Secondary Accessions:
    • Q6IFE4

    Protein attributes for OR52J3 Gene

    Size:
    311 amino acids
    Molecular mass:
    35091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR52J3 Gene

Proteomics data for OR52J3 Gene at MOPED

Post-translational modifications for OR52J3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR52J3 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR52J3 Gene

Domains & Families for OR52J3 Gene

Gene Families for OR52J3 Gene

Protein Domains for OR52J3 Gene

Suggested Antigen Peptide Sequences for OR52J3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NH60

UniProtKB/Swiss-Prot:

O52J3_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR52J3: view

Function for OR52J3 Gene

Molecular function for OR52J3 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR52J3 Gene

genes like me logo Genes that share phenotypes with OR52J3: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR52J3 Gene

Localization for OR52J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR52J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR52J3 Gene COMPARTMENTS Subcellular localization image for OR52J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR52J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR52J3: view

Pathways & Interactions for OR52J3 Gene

genes like me logo Genes that share pathways with OR52J3: view

Pathways by source for OR52J3 Gene

Interacting Proteins for OR52J3 Gene

Gene Ontology (GO) - Biological Process for OR52J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR52J3: view

No data available for SIGNOR curated interactions for OR52J3 Gene

Drugs & Compounds for OR52J3 Gene

(1) Drugs for OR52J3 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Lithium Approved Pharma 0
genes like me logo Genes that share compounds with OR52J3: view

Transcripts for OR52J3 Gene

mRNA/cDNA for OR52J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR52J3 Gene

No ASD Table

Relevant External Links for OR52J3 Gene

GeneLoc Exon Structure for
OR52J3
ECgene alternative splicing isoforms for
OR52J3

Expression for OR52J3 Gene

mRNA expression in normal human tissues for OR52J3 Gene

SOURCE GeneReport for Unigene cluster for OR52J3 Gene Hs.553558

genes like me logo Genes that share expression patterns with OR52J3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR52J3 Gene

Orthologs for OR52J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR52J3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466364 35
  • 99.04 (n)
  • 98.71 (a)
OR52J3 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 84 (a)
OneToMany
-- 36
  • 85 (a)
OneToMany
LOC100852055 35
  • 85.96 (n)
  • 88.71 (a)
dog
(Canis familiaris)
Mammalia OR52J3 35
  • 87.03 (n)
  • 90.68 (a)
-- 36
  • 90 (a)
OneToMany
-- 36
  • 89 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Olfr592 16
Olfr592 36
  • 82 (a)
OneToOne
Olfr592 35
  • 80.8 (n)
  • 82.2 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 75 (a)
OneToMany
-- 36
  • 74 (a)
OneToMany
-- 36
  • 73 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia OR52J3 36
  • 54 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr81 35
  • 80.46 (n)
  • 82.08 (a)
Species with no ortholog for OR52J3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR52J3 Gene

ENSEMBL:
Gene Tree for OR52J3 (if available)
TreeFam:
Gene Tree for OR52J3 (if available)

Paralogs for OR52J3 Gene

(454) SIMAP similar genes for OR52J3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR52J3 Gene

genes like me logo Genes that share paralogs with OR52J3: view

Variants for OR52J3 Gene

Sequence variations from dbSNP and Humsavar for OR52J3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs2500016 - 5,046,754(+) TTTCT(A/G)CAACC reference, missense
rs2500017 - 5,046,907(+) TGGCC(A/G)TCTGT reference, missense
rs2500018 - 5,046,947(+) ATCCC(A/T)AGTGT reference, missense
rs17350764 - 5,047,201(+) GTGCT(A/G)TCTTC reference, missense
rs2500019 -- 5,047,431(+) CGAGA(A/G)CGAGT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR52J3 Gene

Variant ID Type Subtype PubMed ID
dgv340e1 CNV Complex 17122850
nsv526998 CNV Loss 19592680
nsv515951 CNV Loss 19592680
nsv896919 CNV Loss 21882294
nsv896920 CNV Loss 21882294

Variation tolerance for OR52J3 Gene

Residual Variation Intolerance Score: 97% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 23.28; 99.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR52J3 Gene

HapMap Linkage Disequilibrium report
OR52J3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR52J3 Gene

Disorders for OR52J3 Gene

Relevant External Links for OR52J3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR52J3

No disorders were found for OR52J3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR52J3 Gene

Publications for OR52J3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67

Products for OR52J3 Gene

Sources for OR52J3 Gene

Back to Top

Content