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Aliases for OR52J3 Gene

Aliases for OR52J3 Gene

  • Olfactory Receptor, Family 52, Subfamily J, Member 3 2 3
  • Olfactory Receptor OR11-32 3 4
  • Olfactory Receptor 52J3 3
  • OR11-32 3

External Ids for OR52J3 Gene

Summaries for OR52J3 Gene

Entrez Gene Summary for OR52J3 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR52J3 Gene

OR52J3 (Olfactory Receptor, Family 52, Subfamily J, Member 3) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR52D1.

UniProtKB/Swiss-Prot for OR52J3 Gene

  • Odorant receptor.

Gene Wiki entry for OR52J3 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR52J3 Gene

Genomics for OR52J3 Gene

Genomic Location for OR52J3 Gene

Start:
5,046,526 bp from pter
End:
5,047,461 bp from pter
Size:
936 bases
Orientation:
Plus strand

Genomic View for OR52J3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR52J3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR52J3 Gene

Regulatory Elements for OR52J3 Gene

Proteins for OR52J3 Gene

  • Protein details for OR52J3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NH60-O52J3_HUMAN
    Recommended name:
    Olfactory receptor 52J3
    Protein Accession:
    Q8NH60
    Secondary Accessions:
    • Q6IFE4

    Protein attributes for OR52J3 Gene

    Size:
    311 amino acids
    Molecular mass:
    35091 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR52J3 Gene

Proteomics data for OR52J3 Gene at MOPED

Post-translational modifications for OR52J3 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn5

Other Protein References for OR52J3 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR52J3 Gene

Domains for OR52J3 Gene

Gene Families for OR52J3 Gene

HGNC:
  • OR52 :GPCR / Class A : Olfactory receptors

Protein Domains for OR52J3 Gene

UniProtKB/Swiss-Prot:

O52J3_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NH60
genes like me logo Genes that share domains with OR52J3: view

Function for OR52J3 Gene

Molecular function for OR52J3 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR52J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR52J3: view

Phenotypes for OR52J3 Gene

GenomeRNAi human phenotypes for OR52J3:
genes like me logo Genes that share phenotypes with OR52J3: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR52J3 Gene

Localization for OR52J3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR52J3 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR52J3 Gene COMPARTMENTS Subcellular localization image for OR52J3 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR52J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR52J3: view

Pathways for OR52J3 Gene

genes like me logo Genes that share pathways with OR52J3: view

Pathways by source for OR52J3 Gene

Interacting Proteins for OR52J3 Gene

Gene Ontology (GO) - Biological Process for OR52J3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR52J3: view

Compounds for OR52J3 Gene

(1) PharmGKB related drug/compound annotations for OR52J3 Gene

Drug/compound Annotation
lithium CA
genes like me logo Genes that share compounds with OR52J3: view

Transcripts for OR52J3 Gene

mRNA/cDNA for OR52J3 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR52J3 Gene

No ASD Table

Relevant External Links for OR52J3 Gene

GeneLoc Exon Structure for
OR52J3
ECgene alternative splicing isoforms for
OR52J3

Expression for OR52J3 Gene

mRNA expression in normal human tissues for OR52J3 Gene

SOURCE GeneReport for Unigene cluster for OR52J3 Gene Hs.553558

genes like me logo Genes that share expressions with OR52J3: view

Orthologs for OR52J3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR52J3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466364 36
  • 99.04 (n)
  • 98.71 (a)
OR52J3 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 84 (a)
OneToMany
-- 37
  • 85 (a)
OneToMany
LOC100852055 36
  • 85.96 (n)
  • 88.71 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 90 (a)
OneToMany
-- 37
  • 89 (a)
OneToMany
OR52J3 36
  • 87.03 (n)
  • 90.68 (a)
mouse
(Mus musculus)
Mammalia Olfr592 36
  • 80.8 (n)
  • 82.2 (a)
Olfr592 16
Olfr592 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 75 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
-- 37
  • 73 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia OR52J3 37
  • 54 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr81 36
  • 80.46 (n)
  • 82.08 (a)
Species with no ortholog for OR52J3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR52J3 Gene

ENSEMBL:
Gene Tree for OR52J3 (if available)
TreeFam:
Gene Tree for OR52J3 (if available)

Paralogs for OR52J3 Gene

Selected SIMAP similar genes for OR52J3 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR52J3 Gene

genes like me logo Genes that share paralogs with OR52J3: view

Variants for OR52J3 Gene

Sequence variations from dbSNP and Humsavar for OR52J3 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1378736 -- 5,044,857(+) TTAAT(A/G)TAAAA upstream-variant-2KB
rs1378737 -- 5,044,986(+) GTATT(A/G)CATTG upstream-variant-2KB
rs2445280 -- 5,045,124(+) ACGAT(C/T)TAGAA upstream-variant-2KB
rs2500007 -- 5,044,610(+) CACTT(A/G)GAAAT upstream-variant-2KB
rs2500008 -- 5,044,765(+) TTAAC(A/C)ATCTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR52J3 Gene

Variant ID Type Subtype PubMed ID
dgv340e1 CNV Complex 17122850
nsv526998 CNV Loss 19592680
nsv515951 CNV Loss 19592680
nsv896919 CNV Loss 21882294
nsv896920 CNV Loss 21882294

Relevant External Links for OR52J3 Gene

HapMap Linkage Disequilibrium report
OR52J3

Disorders for OR52J3 Gene

No disorders were found for OR52J3 Gene.

No data available for UniProtKB/Swiss-Prot for OR52J3 Gene

Publications for OR52J3 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR52J3 Gene

Sources for OR52J3 Gene

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