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Aliases for OR52H1 Gene

Aliases for OR52H1 Gene

  • Olfactory Receptor, Family 52, Subfamily H, Member 1 2 3
  • Olfactory Receptor OR11-45 3 4
  • Olfactory Receptor OR11-41 Pseudogene 3
  • Olfactory Receptor 52H1 3
  • OR11-41 3
  • OR11-45 3

External Ids for OR52H1 Gene

Previous GeneCards Identifiers for OR52H1 Gene

  • GC11U990496
  • GC11M005531
  • GC11M005522
  • GC11M005526
  • GC11M005534
  • GC11M005555
  • GC11M005559
  • GC11M005563
  • GC11M005566
  • GC11M005570

Summaries for OR52H1 Gene

Entrez Gene Summary for OR52H1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR52H1 Gene

OR52H1 (Olfactory Receptor, Family 52, Subfamily H, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR52D1.

UniProtKB/Swiss-Prot for OR52H1 Gene

  • Odorant receptor.

Gene Wiki entry for OR52H1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR52H1 Gene

Genomics for OR52H1 Gene

Regulatory Elements for OR52H1 Gene

Genomic Location for OR52H1 Gene

5,544,561 bp from pter
5,545,523 bp from pter
963 bases
Minus strand

Genomic View for OR52H1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR52H1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR52H1 Gene

Proteins for OR52H1 Gene

  • Protein details for OR52H1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 52H1
    Protein Accession:
    Secondary Accessions:
    • B9EH26
    • Q6IF79

    Protein attributes for OR52H1 Gene

    320 amino acids
    Molecular mass:
    35592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR52H1 Gene

Proteomics data for OR52H1 Gene at MOPED

Post-translational modifications for OR52H1 Gene

  • Glycosylation at Asn11 and Asn275
  • Modification sites at PhosphoSitePlus

Other Protein References for OR52H1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR52H1 Gene

Domains for OR52H1 Gene

Gene Families for OR52H1 Gene

Protein Domains for OR52H1 Gene

Suggested Antigen Peptide Sequences for OR52H1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR52H1: view

Function for OR52H1 Gene

Molecular function for OR52H1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR52H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR52H1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR52H1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR52H1 Gene

Localization for OR52H1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR52H1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR52H1 Gene COMPARTMENTS Subcellular localization image for OR52H1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR52H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR52H1: view

Pathways for OR52H1 Gene

genes like me logo Genes that share pathways with OR52H1: view

Pathways by source for OR52H1 Gene

Interacting Proteins for OR52H1 Gene

Gene Ontology (GO) - Biological Process for OR52H1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR52H1: view

Transcripts for OR52H1 Gene

mRNA/cDNA for OR52H1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR52H1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR52H1 Gene

No ASD Table

Relevant External Links for OR52H1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR52H1 Gene

mRNA expression in normal human tissues for OR52H1 Gene

SOURCE GeneReport for Unigene cluster for OR52H1 Gene Hs.554540

genes like me logo Genes that share expressions with OR52H1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for OR52H1 Gene

Orthologs for OR52H1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR52H1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC515619 35
  • 90.11 (n)
  • 89.35 (a)
-- 36
  • 89 (a)
-- 36
  • 88 (a)
(Canis familiaris)
Mammalia LOC100684706 35
  • 88.15 (n)
  • 89.52 (a)
-- 36
  • 88 (a)
-- 36
  • 89 (a)
(Mus musculus)
Mammalia Olfr648 35
  • 86.56 (n)
  • 89.68 (a)
Olfr648 16
Olfr648 36
  • 88 (a)
(Pan troglodytes)
Mammalia OR52H1 35
  • 97.92 (n)
  • 95 (a)
OR52H1 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Olr149 35
  • 86.02 (n)
  • 89.03 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
-- 36
  • 77 (a)
Species with no ortholog for OR52H1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR52H1 Gene

Gene Tree for OR52H1 (if available)
Gene Tree for OR52H1 (if available)

Paralogs for OR52H1 Gene

(410) SIMAP similar genes for OR52H1 Gene using alignment to 1 proteins: Pseudogenes for OR52H1 Gene

genes like me logo Genes that share paralogs with OR52H1: view

Variants for OR52H1 Gene

Sequence variations from dbSNP and Humsavar for OR52H1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs368824 -- 5,547,236(-) gctca(C/T)gcctg upstream-variant-2KB
rs369118 -- 5,547,209(-) ggagg(C/T)tgagg upstream-variant-2KB
rs380372 -- 5,547,135(-) ctact(A/G)aaaat upstream-variant-2KB
rs417272 -- 5,547,263(-) GAACT(A/G)CACTG upstream-variant-2KB
rs437746 -- 5,547,189(-) cacct(A/G)aggtc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR52H1 Gene

Variant ID Type Subtype PubMed ID
nsv832057 CNV Loss 17160897
nsv896939 CNV Loss 21882294
nsv510997 CNV Complex 20534489
nsv896940 CNV Loss 21882294

Relevant External Links for OR52H1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR52H1 Gene

Disorders for OR52H1 Gene

No disorders were found for OR52H1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for OR52H1 Gene

Publications for OR52H1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR52H1 Gene

Sources for OR52H1 Gene

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