Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR51V1 Gene

Aliases for OR51V1 Gene

  • Olfactory Receptor, Family 51, Subfamily V, Member 1 2 3
  • Odorant Receptor HOR3beta1 3 4
  • Olfactory Receptor OR11-36 3 4
  • Olfactory Receptor 51A12 3 4
  • OR51A12 3 4
  • Olfactory Receptor 51V1 3
  • OR11-36 3

External Ids for OR51V1 Gene

Previous HGNC Symbols for OR51V1 Gene

  • OR51A12

Previous GeneCards Identifiers for OR51V1 Gene

  • GC00U903061
  • GC11M005187
  • GC11M005177

Summaries for OR51V1 Gene

Entrez Gene Summary for OR51V1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51V1 Gene

OR51V1 (Olfactory Receptor, Family 51, Subfamily V, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51E1.

UniProtKB/Swiss-Prot for OR51V1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51V1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51V1 Gene

Genomics for OR51V1 Gene

Regulatory Elements for OR51V1 Gene

Genomic Location for OR51V1 Gene

Start:
5,199,735 bp from pter
End:
5,200,700 bp from pter
Size:
966 bases
Orientation:
Minus strand

Genomic View for OR51V1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51V1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51V1 Gene

Proteins for OR51V1 Gene

  • Protein details for OR51V1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H2C8-O51V1_HUMAN
    Recommended name:
    Olfactory receptor 51V1
    Protein Accession:
    Q9H2C8
    Secondary Accessions:

    Protein attributes for OR51V1 Gene

    Size:
    321 amino acids
    Molecular mass:
    36749 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51V1 Gene

Proteomics data for OR51V1 Gene at MOPED

Post-translational modifications for OR51V1 Gene

  • Glycosylation at Asn18
  • Modification sites at PhosphoSitePlus

Other Protein References for OR51V1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51V1 Gene

Domains for OR51V1 Gene

Gene Families for OR51V1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51V1 Gene

Suggested Antigen Peptide Sequences for OR51V1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H2C8

UniProtKB/Swiss-Prot:

O51V1_HUMAN :
  • Q9H2C8
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51V1: view

Function for OR51V1 Gene

Molecular function for OR51V1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51V1: view

Phenotypes for OR51V1 Gene

GenomeRNAi human phenotypes for OR51V1:
genes like me logo Genes that share phenotypes with OR51V1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR51V1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51V1 Gene

Localization for OR51V1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51V1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51V1 Gene COMPARTMENTS Subcellular localization image for OR51V1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51V1: view

Pathways for OR51V1 Gene

genes like me logo Genes that share pathways with OR51V1: view

Pathways by source for OR51V1 Gene

Interacting Proteins for OR51V1 Gene

Gene Ontology (GO) - Biological Process for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 11121057
genes like me logo Genes that share ontologies with OR51V1: view

Transcripts for OR51V1 Gene

mRNA/cDNA for OR51V1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR51V1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51V1 Gene

No ASD Table

Relevant External Links for OR51V1 Gene

GeneLoc Exon Structure for
OR51V1
ECgene alternative splicing isoforms for
OR51V1

Expression for OR51V1 Gene

mRNA expression in normal human tissues for OR51V1 Gene

Protein differential expression in normal tissues for OR51V1 Gene

This gene is overexpressed in Bone marrow stromal cell (55.4) and Adipocyte (12.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR51V1 Gene

SOURCE GeneReport for Unigene cluster for OR51V1 Gene Hs.553670

genes like me logo Genes that share expressions with OR51V1: view

Expression partners for OR51V1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR51V1 Gene

Orthologs for OR51V1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR51V1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR51V1 35
  • 85.91 (n)
  • 87.7 (a)
OR51V1 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100855687 35
  • 87.16 (n)
  • 89.19 (a)
OR51V1 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC466373 35
  • 99.27 (n)
  • 98.44 (a)
OR51V1 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr624 16
Olfr624 36
  • 76 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 82 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia OR51V1 36
  • 60 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 36
  • 49 (a)
OneToMany
Species with no ortholog for OR51V1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51V1 Gene

ENSEMBL:
Gene Tree for OR51V1 (if available)
TreeFam:
Gene Tree for OR51V1 (if available)

Paralogs for OR51V1 Gene

Paralogs for OR51V1 Gene

Selected SIMAP similar genes for OR51V1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR51V1: view

Variants for OR51V1 Gene

Sequence variations from dbSNP and Humsavar for OR51V1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs7930968 -- 5,199,480(+) CATTT(C/G)AGGCA downstream-variant-500B
rs7933098 -- 5,199,607(+) TTTAA(A/G)GTCAT downstream-variant-500B
rs7933549 - 5,200,003(+) GGACT(A/G)ACTTA reference, missense
rs7933718 -- 5,200,194(+) CAGAT(A/G)ATGGG reference, synonymous-codon
rs7937649 -- 5,201,149(+) TTTCC(A/G)TCATT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51V1 Gene

Variant ID Type Subtype PubMed ID
nsv896920 CNV Loss 21882294
dgv1023n71 CNV Loss 21882294
nsv896925 CNV Gain 21882294
nsv896929 CNV Loss 21882294
nsv523914 CNV Loss 19592680

Relevant External Links for OR51V1 Gene

HapMap Linkage Disequilibrium report
OR51V1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51V1 Gene

Disorders for OR51V1 Gene

Relevant External Links for OR51V1

Genetic Association Database (GAD)
OR51V1

No disorders were found for OR51V1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR51V1 Gene

Publications for OR51V1 Gene

  1. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. Genome-wide and fine-resolution association analysis of malaria in West Africa. (PMID: 19465909) Jallow M. … . (Nat. Genet. 2009) 48
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR51V1 Gene

Sources for OR51V1 Gene

Back to Top

Content