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Aliases for OR51V1 Gene

Aliases for OR51V1 Gene

  • Olfactory Receptor Family 51 Subfamily V Member 1 2 3 5
  • Odorant Receptor HOR3beta1 3 4
  • Olfactory Receptor OR11-36 3 4
  • Olfactory Receptor 51A12 3 4
  • OR51A12 3 4
  • Olfactory Receptor, Family 51, Subfamily V, Member 1 2
  • Olfactory Receptor 51V1 3
  • OR11-36 3

External Ids for OR51V1 Gene

Previous HGNC Symbols for OR51V1 Gene

  • OR51A12

Previous GeneCards Identifiers for OR51V1 Gene

  • GC00U903061
  • GC11M005187
  • GC11M005177

Summaries for OR51V1 Gene

Entrez Gene Summary for OR51V1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51V1 Gene

OR51V1 (Olfactory Receptor Family 51 Subfamily V Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51G1.

UniProtKB/Swiss-Prot for OR51V1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51V1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51V1 Gene

Genomics for OR51V1 Gene

Regulatory Elements for OR51V1 Gene

Enhancers for OR51V1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F005287 1.3 FANTOM5 ENCODE 10.9 -88.0 -88042 3.2 YBX3 TBP HDAC1 CBX3 ATF1 ARNT TBL1XR1 GATA2 FOS CREM HBD HBG2 HBG1 ENSG00000224091 HBBP1 HBB OR51V1 ENSG00000221031 OR52A4P OR51M1
GH11F005274 1.2 FANTOM5 ENCODE 10.2 -74.8 -74842 2.2 TBP HDAC1 CBX3 ATF1 ARNT TBL1XR1 CHAMP1 GATA2 CREM ZBTB2 HBD HBG2 HBB HBG1 HBBP1 ENSG00000221031 OR51V1 OR51B4 GC11M005280 ENSG00000279346
GH11F005361 1.1 Ensembl ENCODE 10.1 -164.8 -164834 7.4 CTCF HINFP DDX20 JUN PTRF CHAMP1 IRF9 ZNF316 NFE2 MAFK ENSG00000224091 OR51B5 OR51M1 OR51B4 OR51J1 OR51V1 OR52A4P HBB ENSG00000221031 OR51I2
GH11F005284 0.8 ENCODE 10.8 -85.2 -85158 1.8 TAL1 RELA ZKSCAN1 ZNF316 NCOR1 POLR2A NR2F6 STAT1 ZBTB11 NCOA1 ENSG00000224091 HBB ENSG00000221031 HBBP1 HBD OR51V1 HBG1 OR51B5 GC11M005283 LCRB
GH11F005379 0.4 FANTOM5 12.9 -179.3 -179292 0.0 ZNF316 OR51V1 OR51T1 HBB OR51B5 OR51G1 OR56B1 OR52J3 OR51L1 OR52N4 OR52D1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR51V1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR51V1 Gene

5,199,735 bp from pter
5,200,700 bp from pter
966 bases
Minus strand

Genomic View for OR51V1 Gene

Genes around OR51V1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51V1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51V1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51V1 Gene

Proteins for OR51V1 Gene

  • Protein details for OR51V1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51V1
    Protein Accession:

    Protein attributes for OR51V1 Gene

    321 amino acids
    Molecular mass:
    36749 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51V1 Gene

Post-translational modifications for OR51V1 Gene

  • Glycosylation at Asn 18
  • Modification sites at PhosphoSitePlus

Other Protein References for OR51V1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51V1 Gene

Domains & Families for OR51V1 Gene

Gene Families for OR51V1 Gene

Protein Domains for OR51V1 Gene

Suggested Antigen Peptide Sequences for OR51V1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51V1: view

Function for OR51V1 Gene

Molecular function for OR51V1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51V1: view
genes like me logo Genes that share phenotypes with OR51V1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51V1 Gene

Localization for OR51V1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51V1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR51V1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51V1: view

Pathways & Interactions for OR51V1 Gene

genes like me logo Genes that share pathways with OR51V1: view

Pathways by source for OR51V1 Gene

Interacting Proteins for OR51V1 Gene

Gene Ontology (GO) - Biological Process for OR51V1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA,IBA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51V1: view

No data available for SIGNOR curated interactions for OR51V1 Gene

Transcripts for OR51V1 Gene

mRNA/cDNA for OR51V1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51V1 Gene

No ASD Table

Relevant External Links for OR51V1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51V1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR51V1 Gene

Protein differential expression in normal tissues from HIPED for OR51V1 Gene

This gene is overexpressed in Bone marrow stromal cell (55.4) and Adipocyte (12.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR51V1 Gene

Protein tissue co-expression partners for OR51V1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR51V1 Gene:


SOURCE GeneReport for Unigene cluster for OR51V1 Gene:

genes like me logo Genes that share expression patterns with OR51V1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR51V1 Gene

Orthologs for OR51V1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR51V1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466373 34
  • 99.27 (n)
OR51V1 35
  • 98 (a)
(Canis familiaris)
Mammalia LOC100855687 34
  • 87.16 (n)
OR51V1 35
  • 85 (a)
(Bos Taurus)
Mammalia OR51V1 34 35
  • 85.91 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 82 (a)
(Mus musculus)
Mammalia Or51v8 55 Olfr624 35
  • 76 (a)
Or51v14 55 Olfr620
  • chr7:103,611,413-103,612,351
Or51v15-ps 55 Olfr621-ps1
  • chr7:103,629,018-103,629,943
Or51v16-ps 55 Olfr626-ps1
  • chr7:103,691,755-103,692,102
(Ornithorhynchus anatinus)
Mammalia OR51V1 35
  • 60 (a)
(Gallus gallus)
Aves -- 35
  • 49 (a)
Species where no ortholog for OR51V1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51V1 Gene

Gene Tree for OR51V1 (if available)
Gene Tree for OR51V1 (if available)

Paralogs for OR51V1 Gene

(377) SIMAP similar genes for OR51V1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR51V1: view

Variants for OR51V1 Gene

Sequence variations from dbSNP and Humsavar for OR51V1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10837569 -- 5,202,205(+) TTCAA(C/T)TTTAA upstream-variant-2KB
rs11036212 -- 5,200,595(+) GGAAA(A/G)CCAGG reference, missense
rs11036224 -- 5,202,506(+) GTCCC(C/T)TTTCT upstream-variant-2KB
rs11036225 -- 5,202,641(+) TCTAC(C/G)ATTTC upstream-variant-2KB
rs11036227 -- 5,202,690(+) TTGCC(C/T)GTCTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51V1 Gene

Variant ID Type Subtype PubMed ID
dgv1041n100 CNV loss 25217958
dgv182e214 CNV loss 21293372
esv2760169 CNV gain+loss 21179565
esv3891916 CNV loss 25118596
esv3891917 CNV loss 25118596
nsv1048350 CNV gain 25217958
nsv523914 CNV loss 19592680

Variation tolerance for OR51V1 Gene

Residual Variation Intolerance Score: 75% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.37; 76.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR51V1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51V1 Gene

Disorders for OR51V1 Gene

Relevant External Links for OR51V1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR51V1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51V1 Gene

Publications for OR51V1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4 64
  3. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. (PMID: 26354767) Bailey M.L. … Hieter P. (Genetics 2015) 3 64
  4. Genome-wide and fine-resolution association analysis of malaria in West Africa. (PMID: 19465909) Jallow M. … . (Nat. Genet. 2009) 46 64
  5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 64

Products for OR51V1 Gene

Sources for OR51V1 Gene

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