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Aliases for OR51S1 Gene

Aliases for OR51S1 Gene

  • Olfactory Receptor, Family 51, Subfamily S, Member 1 2 3
  • Olfactory Receptor OR11-24 3 4
  • Olfactory Receptor 51S1 3
  • OR11-24 3

External Ids for OR51S1 Gene

Summaries for OR51S1 Gene

Entrez Gene Summary for OR51S1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51S1 Gene

OR51S1 (Olfactory Receptor, Family 51, Subfamily S, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR51S1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51S1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51S1 Gene

Genomics for OR51S1 Gene

Genomic Location for OR51S1 Gene

Start:
4,848,237 bp from pter
End:
4,849,208 bp from pter
Size:
972 bases
Orientation:
Minus strand

Genomic View for OR51S1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51S1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51S1 Gene

Regulatory Elements for OR51S1 Gene

Proteins for OR51S1 Gene

  • Protein details for OR51S1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGJ8-O51S1_HUMAN
    Recommended name:
    Olfactory receptor 51S1
    Protein Accession:
    Q8NGJ8
    Secondary Accessions:
    • B9EGZ1
    • Q6IFI2

    Protein attributes for OR51S1 Gene

    Size:
    323 amino acids
    Molecular mass:
    35313 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51S1 Gene

Proteomics data for OR51S1 Gene at MOPED

Post-translational modifications for OR51S1 Gene

Other Protein References for OR51S1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51S1 Gene

Domains for OR51S1 Gene

Gene Families for OR51S1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

UniProtKB/Swiss-Prot:

O51S1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGJ8
genes like me logo Genes that share domains with OR51S1: view

Function for OR51S1 Gene

Molecular function for OR51S1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51S1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51S1 Gene

Localization for OR51S1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51S1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51S1 Gene COMPARTMENTS Subcellular localization image for OR51S1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51S1: view

Pathways for OR51S1 Gene

genes like me logo Genes that share pathways with OR51S1: view

Pathways by source for OR51S1 Gene

Interacting Proteins for OR51S1 Gene

Gene Ontology (GO) - Biological Process for OR51S1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51S1: view

Transcripts for OR51S1 Gene

mRNA/cDNA for OR51S1 Gene

(2) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51S1 Gene

No ASD Table

Relevant External Links for OR51S1 Gene

GeneLoc Exon Structure for
OR51S1
ECgene alternative splicing isoforms for
OR51S1

Expression for OR51S1 Gene

mRNA expression in normal human tissues for OR51S1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR51S1 Gene

SOURCE GeneReport for Unigene cluster for OR51S1 Gene Hs.553561

genes like me logo Genes that share expressions with OR51S1: view

Orthologs for OR51S1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51S1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 37
  • 81 (a)
OneToMany
-- 37
  • 82 (a)
OneToMany
OR51S1 36
  • 85.71 (n)
  • 81.99 (a)
dog
(Canis familiaris)
Mammalia LOC100684755 36
  • 85.36 (n)
  • 82.87 (a)
OR51S1 37
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr571 36
  • 81.26 (n)
  • 80.12 (a)
Olfr571 16
Olfr571 37
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR51S1 37
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr49 36
  • 82.41 (n)
  • 80.78 (a)
Species with no ortholog for OR51S1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51S1 Gene

ENSEMBL:
Gene Tree for OR51S1 (if available)
TreeFam:
Gene Tree for OR51S1 (if available)

Paralogs for OR51S1 Gene

Selected SIMAP similar genes for OR51S1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR51S1: view

No data available for Paralogs for OR51S1 Gene

Variants for OR51S1 Gene

Sequence variations from dbSNP and Humsavar for OR51S1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1368823 -- 4,850,276(-) CTTTG(A/G)ATTAT upstream-variant-2KB
rs1368824 -- 4,850,251(-) CCTGG(A/G)ACATC upstream-variant-2KB
rs2412395 -- 4,849,806(+) CTTAA(C/T)TTTGC upstream-variant-2KB
rs7117260 - 4,848,676(+) GTGGG(A/C)GGCAG missense, reference
rs7117389 -- 4,848,762(+) TTGCT(A/G)ATTAC synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for OR51S1 Gene

Variant ID Type Subtype PubMed ID
esv2673268 CNV Deletion 23128226
nsv467666 CNV Loss 19166990
nsv7651 CNV Insertion 18451855

Relevant External Links for OR51S1 Gene

HapMap Linkage Disequilibrium report
OR51S1

Disorders for OR51S1 Gene

No disorders were found for OR51S1 Gene.

No data available for UniProtKB/Swiss-Prot for OR51S1 Gene

Publications for OR51S1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR51S1 Gene

  • antibodies-online peptides for OR51S1
  • antibodies-online antibodies for OR51S1
  • antibodies-online kits for OR51S1

Sources for OR51S1 Gene

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