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Aliases for OR51M1 Gene

Aliases for OR51M1 Gene

  • Olfactory Receptor Family 51 Subfamily M Member 1 2 3 5
  • Odorant Receptor HOR5beta7 3 4
  • Olfactory Receptor OR11-40 3 4
  • Olfactory Receptor, Family 51, Subfamily M, Member 1 2
  • Olfactory Receptor 51M1 3
  • HOR5Beta7 3
  • OR11-40 3

External Ids for OR51M1 Gene

Previous GeneCards Identifiers for OR51M1 Gene

  • GC11U990338
  • GC11P005348
  • GC11P005343
  • GC11P005410

Summaries for OR51M1 Gene

Entrez Gene Summary for OR51M1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51M1 Gene

OR51M1 (Olfactory Receptor Family 51 Subfamily M Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51G1.

UniProtKB/Swiss-Prot for OR51M1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51M1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51M1 Gene

Genomics for OR51M1 Gene

Regulatory Elements for OR51M1 Gene

Enhancers for OR51M1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F005287 1.3 FANTOM5 ENCODE 9.2 -100.6 -100636 3.2 YBX3 TBP HDAC1 CBX3 ATF1 ARNT TBL1XR1 GATA2 FOS CREM HBD HBG2 HBG1 ENSG00000224091 HBBP1 HBB OR51V1 ENSG00000221031 OR52A4P OR51M1
GH11F005361 1.1 Ensembl ENCODE 10.7 -23.8 -23844 7.4 CTCF HINFP DDX20 JUN PTRF CHAMP1 IRF9 ZNF316 NFE2 MAFK ENSG00000224091 OR51B5 OR51M1 OR51B4 OR51J1 OR51V1 OR52A4P HBB ENSG00000221031 OR51I2
GH11F005546 0.3 FANTOM5 7.5 +156.9 156869 0.1 OR56A1 OR56A3 OR51Q1 OR52E8 OR52N1 OR56A4 OR52N4 OR52E2 OR52E4 OR52A1
GH11F005328 0.3 FANTOM5 3 -60.2 -60199 0.4 OR51G1 OR51T1 OR52N2 OR52N4 OR52D1 OR52J3 MMP26 OR51L1 OR51B2 OR51M1
GH11F005379 0.4 FANTOM5 1.6 -9.4 -9386 0.0 ZNF316 OR51V1 OR51T1 HBB OR51B5 OR51G1 OR56B1 OR52J3 OR51L1 OR52N4 OR52D1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR51M1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR51M1 Gene

Chromosome:
11
Start:
5,389,377 bp from pter
End:
5,390,434 bp from pter
Size:
1,058 bases
Orientation:
Plus strand

Genomic View for OR51M1 Gene

Genes around OR51M1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51M1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51M1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51M1 Gene

Proteins for OR51M1 Gene

  • Protein details for OR51M1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H341-O51M1_HUMAN
    Recommended name:
    Olfactory receptor 51M1
    Protein Accession:
    Q9H341
    Secondary Accessions:
    • Q6IF80

    Protein attributes for OR51M1 Gene

    Size:
    326 amino acids
    Molecular mass:
    36669 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51M1 Gene

Post-translational modifications for OR51M1 Gene

  • Glycosylation at Asn 16
  • Modification sites at PhosphoSitePlus

Other Protein References for OR51M1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51M1 Gene

Domains & Families for OR51M1 Gene

Gene Families for OR51M1 Gene

Protein Domains for OR51M1 Gene

Suggested Antigen Peptide Sequences for OR51M1 Gene

Graphical View of Domain Structure for InterPro Entry

Q9H341

UniProtKB/Swiss-Prot:

O51M1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51M1: view

Function for OR51M1 Gene

Molecular function for OR51M1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51M1: view
genes like me logo Genes that share phenotypes with OR51M1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51M1 Gene

Localization for OR51M1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51M1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR51M1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51M1: view

Pathways & Interactions for OR51M1 Gene

genes like me logo Genes that share pathways with OR51M1: view

Pathways by source for OR51M1 Gene

Interacting Proteins for OR51M1 Gene

Gene Ontology (GO) - Biological Process for OR51M1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA,IBA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51M1: view

No data available for SIGNOR curated interactions for OR51M1 Gene

Transcripts for OR51M1 Gene

mRNA/cDNA for OR51M1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51M1 Gene

No ASD Table

Relevant External Links for OR51M1 Gene

GeneLoc Exon Structure for
OR51M1
ECgene alternative splicing isoforms for
OR51M1

Expression for OR51M1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR51M1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR51M1 Gene:

OR51M1

SOURCE GeneReport for Unigene cluster for OR51M1 Gene:

Hs.553731
genes like me logo Genes that share expression patterns with OR51M1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR51M1 Gene

Orthologs for OR51M1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR51M1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466376 34
  • 98.56 (n)
OR51M1 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR51M1 34 35
  • 85.44 (n)
cow
(Bos Taurus)
Mammalia LOC617878 34
  • 84.37 (n)
OR51M1 35
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or51m1 55 Olfr631 34 16 35
  • 83.7 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 50 (a)
ManyToMany
chicken
(Gallus gallus)
Aves COR3BETA 35
  • 52 (a)
OneToOne
Species where no ortholog for OR51M1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51M1 Gene

ENSEMBL:
Gene Tree for OR51M1 (if available)
TreeFam:
Gene Tree for OR51M1 (if available)

Paralogs for OR51M1 Gene

(422) SIMAP similar genes for OR51M1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR51M1: view

Variants for OR51M1 Gene

Sequence variations from dbSNP and Humsavar for OR51M1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10742660 -- 5,387,450(+) ATAAA(C/T)GTGGA intron-variant, upstream-variant-2KB
rs10742661 -- 5,387,525(+) TCGAA(A/G)CTCAC intron-variant, upstream-variant-2KB
rs10768903 -- 5,388,865(+) AACCC(C/T)AGGAC intron-variant, upstream-variant-2KB
rs10768906 -- 5,390,349(+) ATCAA(A/G)TTCCT intron-variant, reference, synonymous-codon
rs10768907 -- 5,390,350(+) TCAAG(C/T)TCCTA intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR51M1 Gene

Variant ID Type Subtype PubMed ID
nsv832057 CNV loss 17160897
nsv524400 CNV loss 19592680
nsv1048608 CNV gain 25217958
nsv1046068 CNV gain 25217958
nsv1044243 CNV loss 25217958
esv2761646 CNV loss 21179565
esv22160 CNV loss 19812545

Variation tolerance for OR51M1 Gene

Residual Variation Intolerance Score: 98.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.16; 92.34% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR51M1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR51M1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51M1 Gene

Disorders for OR51M1 Gene

Relevant External Links for OR51M1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR51M1

No disorders were found for OR51M1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51M1 Gene

Publications for OR51M1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  4. Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. (PMID: 10220430) Bulger M. … Groudine M. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3 64

Products for OR51M1 Gene

Sources for OR51M1 Gene

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