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Aliases for OR51L1 Gene

Aliases for OR51L1 Gene

  • Olfactory Receptor, Family 51, Subfamily L, Member 1 2 3
  • Olfactory Receptor OR11-31 3 4
  • Olfactory Receptor 51L1 3
  • OR11-31 3

External Ids for OR51L1 Gene

Summaries for OR51L1 Gene

Entrez Gene Summary for OR51L1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51L1 Gene

OR51L1 (Olfactory Receptor, Family 51, Subfamily L, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51L1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51L1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51L1 Gene

Genomics for OR51L1 Gene

Genomic Location for OR51L1 Gene

Start:
4,998,983 bp from pter
End:
4,999,930 bp from pter
Size:
948 bases
Orientation:
Plus strand

Genomic View for OR51L1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51L1 Gene

Regulatory Elements for OR51L1 Gene

Proteins for OR51L1 Gene

  • Protein details for OR51L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGJ5-O51L1_HUMAN
    Recommended name:
    Olfactory receptor 51L1
    Protein Accession:
    Q8NGJ5
    Secondary Accessions:
    • Q6IFE5

    Protein attributes for OR51L1 Gene

    Size:
    315 amino acids
    Molecular mass:
    35369 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51L1 Gene

Proteomics data for OR51L1 Gene at MOPED

Post-translational modifications for OR51L1 Gene

Other Protein References for OR51L1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51L1 Gene

Domains for OR51L1 Gene

Gene Families for OR51L1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51L1 Gene

UniProtKB/Swiss-Prot:

O51L1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGJ5
genes like me logo Genes that share domains with OR51L1: view

Function for OR51L1 Gene

Molecular function for OR51L1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51L1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51L1 Gene

Localization for OR51L1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51L1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51L1 Gene COMPARTMENTS Subcellular localization image for OR51L1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51L1: view

Pathways for OR51L1 Gene

genes like me logo Genes that share pathways with OR51L1: view

Pathways by source for OR51L1 Gene

Interacting Proteins for OR51L1 Gene

Gene Ontology (GO) - Biological Process for OR51L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51L1: view

Transcripts for OR51L1 Gene

mRNA/cDNA for OR51L1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51L1 Gene

No ASD Table

Relevant External Links for OR51L1 Gene

GeneLoc Exon Structure for
OR51L1
ECgene alternative splicing isoforms for
OR51L1

Expression for OR51L1 Gene

mRNA expression in normal human tissues for OR51L1 Gene

SOURCE GeneReport for Unigene cluster for OR51L1 Gene Hs.553559

genes like me logo Genes that share expressions with OR51L1: view

Orthologs for OR51L1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51L1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466361 36
  • 99.37 (n)
  • 98.73 (a)
OR51L1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC788739 36
  • 87.82 (n)
  • 86.54 (a)
OR51L1 37
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC610109 36
  • 88.1 (n)
  • 87.14 (a)
OR51L1 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr609 37
  • 54 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 55 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia OR51L1 37
  • 53 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr78 36
  • 84.44 (n)
  • 87.94 (a)
Species with no ortholog for OR51L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51L1 Gene

ENSEMBL:
Gene Tree for OR51L1 (if available)
TreeFam:
Gene Tree for OR51L1 (if available)

Paralogs for OR51L1 Gene

Selected SIMAP similar genes for OR51L1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR51L1 Gene

genes like me logo Genes that share paralogs with OR51L1: view

Variants for OR51L1 Gene

Sequence variations from dbSNP and Humsavar for OR51L1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs2445290 -- 4,999,186(+) ATCTT(A/G)GCAGT reference, synonymous-codon
rs2445291 -- 5,000,177(+) GCTAA(A/G)TCAAG downstream-variant-500B
rs3066001 -- 4,998,195(+) cacac(-/ACACAC)gcata upstream-variant-2KB
rs7933046 -- 4,997,521(+) GAATT(A/G)CTGAG upstream-variant-2KB
rs10768448 - 4,999,569(+) CAGGA(C/T)CAACA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR51L1 Gene

Variant ID Type Subtype PubMed ID
dgv340e1 CNV Complex 17122850
nsv526998 CNV Loss 19592680
esv33877 CNV Gain 17666407

Relevant External Links for OR51L1 Gene

HapMap Linkage Disequilibrium report
OR51L1
Human Gene Mutation Database (HGMD)
OR51L1

Disorders for OR51L1 Gene

No disorders were found for OR51L1 Gene.

No data available for UniProtKB/Swiss-Prot for OR51L1 Gene

Publications for OR51L1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Genetic determinants of haemolysis in sickle cell anaemia. (PMID: 23406172) Milton J.N. … Steinberg M.H. (Br. J. Haematol. 2013) 3

Products for OR51L1 Gene

Sources for OR51L1 Gene

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