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Aliases for OR51J1 Gene

Aliases for OR51J1 Gene

  • Olfactory Receptor Family 51 Subfamily J Member 1 (Gene/Pseudogene) 2 3 5
  • Odorant Receptor HOR5beta8 3 4
  • Olfactory Receptor 51J2 3 4
  • OR51J1P 3 4
  • OR51J2 3 4
  • Olfactory Receptor, Family 51, Subfamily J, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 51, Subfamily J, Member 1 Pseudogene 3
  • Olfactory Receptor, Family 51, Subfamily J, Member 1 2
  • Olfactory Receptor, Family 51, Subfamily J, Member 2 3
  • Olfactory Receptor 51J1 3

External Ids for OR51J1 Gene

Previous HGNC Symbols for OR51J1 Gene

  • OR51J2
  • OR51J1P

Previous GeneCards Identifiers for OR51J1 Gene

  • GC11P005389
  • GC11P005380
  • GC11P005423

Summaries for OR51J1 Gene

Entrez Gene Summary for OR51J1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jan 2017]

GeneCards Summary for OR51J1 Gene

OR51J1 (Olfactory Receptor Family 51 Subfamily J Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR51J1 Gene

  • Odorant receptor.

Additional gene information for OR51J1 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51J1 Gene

Genomics for OR51J1 Gene

GeneHancer (GH) Regulatory Elements for OR51J1 Gene

Promoters and enhancers for OR51J1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11I005361 Enhancer 0.9 Ensembl ENCODE 10.2 -37.0 -36964 7.4 JUN RELA CHAMP1 IRF9 CC2D1A ZNF316 POLR2A NFE2 MAFK CAVIN1 ENSG00000224091 OR51B5 OR51B4 OR51J1 OR51V1 OR52A4P HBB ENSG00000221031 OR51I2 ENSG00000167355
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around OR51J1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OR51J1 Gene

Genomic Locations for OR51J1 Gene
1,175 bases
Plus strand

Genomic View for OR51J1 Gene

Genes around OR51J1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51J1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51J1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51J1 Gene

Proteins for OR51J1 Gene

  • Protein details for OR51J1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51J1
    Protein Accession:

    Protein attributes for OR51J1 Gene

    316 amino acids
    Molecular mass:
    34838 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51J1 Gene

Post-translational modifications for OR51J1 Gene

No Post-translational modifications

Other Protein References for OR51J1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51J1 Gene

Domains & Families for OR51J1 Gene

Gene Families for OR51J1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR51J1 Gene

Suggested Antigen Peptide Sequences for OR51J1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51J1: view

Function for OR51J1 Gene

Molecular function for OR51J1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51J1: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51J1 Gene

Localization for OR51J1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51J1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR51J1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IBA,TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51J1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR51J1 Gene

Pathways & Interactions for OR51J1 Gene

genes like me logo Genes that share pathways with OR51J1: view

Pathways by source for OR51J1 Gene

Interacting Proteins for OR51J1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000332473 for OR51J1 Gene via STRING

Gene Ontology (GO) - Biological Process for OR51J1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IBA --
GO:0007186 G-protein coupled receptor signaling pathway TAS --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51J1: view

No data available for SIGNOR curated interactions for OR51J1 Gene

Drugs & Compounds for OR51J1 Gene

No Compound Related Data Available

Transcripts for OR51J1 Gene

mRNA/cDNA for OR51J1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51J1 Gene

No ASD Table

Relevant External Links for OR51J1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51J1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR51J1 Gene

mRNA differential expression in normal tissues according to GTEx for OR51J1 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x12.7) and Brain - Cerebellum (x11.3).

NURSA nuclear receptor signaling pathways regulating expression of OR51J1 Gene:

genes like me logo Genes that share expression patterns with OR51J1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR51J1 Gene

Orthologs for OR51J1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR51J1 Gene

Organism Taxonomy Gene Similarity Type Details
(Monodelphis domestica)
Mammalia -- 34
  • 40 (a)
-- 34
  • 39 (a)
-- 34
  • 39 (a)
-- 34
  • 38 (a)
-- 34
  • 36 (a)
(Canis familiaris)
Mammalia -- 34
  • 39 (a)
-- 34
  • 34 (a)
(Mus musculus)
Mammalia Olfr616 34
  • 39 (a)
Olfr615 34
  • 37 (a)
Olfr613 34
  • 34 (a)
(Bos Taurus)
Mammalia OR51J1 34
  • 33 (a)
(Gallus gallus)
Aves OR51J1 34
  • 28 (a)
(Danio rerio)
Actinopterygii CABZ01018874.1 34
  • 23 (a)
or112-1 34
  • 23 (a)
Species where no ortholog for OR51J1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR51J1 Gene

Gene Tree for OR51J1 (if available)
Gene Tree for OR51J1 (if available)

Paralogs for OR51J1 Gene

No data available for Paralogs for OR51J1 Gene

Variants for OR51J1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR51J1 Gene

A nonsynonymous SNP at position Cys-100, a highly conserved amino-acid, in the gene coding for this protein is responsible for functional diversity.

Sequence variations from dbSNP and Humsavar for OR51J1 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1909261 -- p.Cys100Tyr

Variation tolerance for OR51J1 Gene

Gene Damage Index Score: 18.10; 98.45% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for OR51J1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR51J1 Gene

Disorders for OR51J1 Gene

Additional Disease Information for OR51J1

No disorders were found for OR51J1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51J1 Gene

Publications for OR51J1 Gene

  1. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M … Hardison R (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4 58
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T … Lancet D (BMC genomics 2012) 3 58
  3. Exploration of human ORFeome: high-throughput preparation of ORF clones and efficient characterization of their protein products. (PMID: 18316326) Nagase T … Ohara O (DNA research : an international journal for rapid publication of reports on genes and genomes 2008) 3 58
  4. Genetic elucidation of human hyperosmia to isovaleric acid. (PMID: 17973576) Menashe I … Lancet D (PLoS biology 2007) 4 58
  5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor TD … Sakaki Y (Nature 2006) 4 58

Products for OR51J1 Gene

Sources for OR51J1 Gene

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