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Aliases for OR51I1 Gene

Aliases for OR51I1 Gene

  • Olfactory Receptor Family 51 Subfamily I Member 1 2 3 5
  • Odorant Receptor HOR5beta11 3 4
  • Olfactory Receptor OR11-39 3 4
  • Olfactory Receptor, Family 51, Subfamily I, Member 1 2
  • Olfactory Receptor 51I1 3
  • HOR5Beta11 3

External Ids for OR51I1 Gene

Previous GeneCards Identifiers for OR51I1 Gene

  • GC11U990514
  • GC11M005427
  • GC11M005409
  • GC11M005400
  • GC11M005418

Summaries for OR51I1 Gene

Entrez Gene Summary for OR51I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51I1 Gene

OR51I1 (Olfactory Receptor Family 51 Subfamily I Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51I1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51I1 Gene

Additional gene information for OR51I1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51I1 Gene

Genomics for OR51I1 Gene

Regulatory Elements for OR51I1 Gene

Enhancers for OR51I1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11H005379 0.3 FANTOM5 1.9 +61.6 61562 0 OR51V1 OR51T1 HBB OR51B5 OR51G1 OR56B1 OR52J3 OR51L1 OR52N4 OR52D1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OR51I1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for OR51I1 Gene

Genomic Locations for OR51I1 Gene
1,012 bases
Minus strand

Genomic View for OR51I1 Gene

Genes around OR51I1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51I1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51I1 Gene

Proteins for OR51I1 Gene

  • Protein details for OR51I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51I1
    Protein Accession:
    Secondary Accessions:
    • B9EKW2
    • Q6IF33

    Protein attributes for OR51I1 Gene

    314 amino acids
    Molecular mass:
    35484 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51I1 Gene

Post-translational modifications for OR51I1 Gene

No Post-translational modifications

Other Protein References for OR51I1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51I1 Gene

Domains & Families for OR51I1 Gene

Gene Families for OR51I1 Gene

Human Protein Atlas (HPA):
  • G-protein coupled receptors
  • Predicted membrane proteins

Protein Domains for OR51I1 Gene

Suggested Antigen Peptide Sequences for OR51I1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51I1: view

Function for OR51I1 Gene

Molecular function for OR51I1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

Phenotypes for OR51I1 Gene

genes like me logo Genes that share phenotypes with OR51I1: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51I1 Gene

Localization for OR51I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OR51I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS,IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for OR51I1 Gene

Pathways & Interactions for OR51I1 Gene

genes like me logo Genes that share pathways with OR51I1: view

Pathways by source for OR51I1 Gene

Interacting Proteins for OR51I1 Gene

Gene Ontology (GO) - Biological Process for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IBA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51I1: view

No data available for SIGNOR curated interactions for OR51I1 Gene

Drugs & Compounds for OR51I1 Gene

No Compound Related Data Available

Transcripts for OR51I1 Gene

mRNA/cDNA for OR51I1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR51I1 Gene

No ASD Table

Relevant External Links for OR51I1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51I1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OR51I1 Gene

mRNA differential expression in normal tissues according to GTEx for OR51I1 Gene

This gene is overexpressed in Testis (x7.8).

NURSA nuclear receptor signaling pathways regulating expression of OR51I1 Gene:


SOURCE GeneReport for Unigene cluster for OR51I1 Gene:

genes like me logo Genes that share expression patterns with OR51I1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OR51I1 Gene

Orthologs for OR51I1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51I1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC466378 33
  • 99.15 (n)
OR51I1 34
  • 96 (a)
(Bos Taurus)
Mammalia OR51I1 33 34
  • 86.5 (n)
(Rattus norvegicus)
Mammalia Olr142 33
  • 85.2 (n)
(Mus musculus)
Mammalia Or51i1 52 Olfr640 33 16 34
  • 83.71 (n)
(Monodelphis domestica)
Mammalia OR51I1 34
  • 83 (a)
(Canis familiaris)
Mammalia -- 34
  • 60 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 56 (a)
Species where no ortholog for OR51I1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51I1 Gene

Gene Tree for OR51I1 (if available)
Gene Tree for OR51I1 (if available)

Paralogs for OR51I1 Gene

Paralogs for OR51I1 Gene

(410) SIMAP similar genes for OR51I1 Gene using alignment to 1 proteins: Pseudogenes for OR51I1 Gene

genes like me logo Genes that share paralogs with OR51I1: view

Variants for OR51I1 Gene

Sequence variations from dbSNP and Humsavar for OR51I1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000134876 -- 5,440,654(+) AGCAT(A/G)GGTGG intron-variant, reference, synonymous-codon
rs1001598305 -- 5,440,922(+) AAATG(C/T)TGTTA intron-variant, reference, missense
rs1002573416 -- 5,442,468(+) ATATT(C/G)ATTCT intron-variant, upstream-variant-2KB
rs1002604449 -- 5,442,103(+) CTGGT(A/C)TATGA intron-variant, upstream-variant-2KB
rs1003597074 -- 5,443,360(+) TTTCT(C/T)TCTCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51I1 Gene

Variant ID Type Subtype PubMed ID
dgv1042n100 CNV gain 25217958
esv2664205 CNV deletion 23128226
esv2759800 CNV loss 17122850
esv34391 CNV loss 17911159
esv3625225 CNV loss 21293372
nsv1039047 CNV gain 25217958
nsv1046068 CNV gain 25217958
nsv1048608 CNV gain 25217958
nsv832057 CNV loss 17160897

Variation tolerance for OR51I1 Gene

Residual Variation Intolerance Score: 95.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.97; 98.40% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR51I1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51I1 Gene

Disorders for OR51I1 Gene

Relevant External Links for OR51I1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR51I1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51I1 Gene

Publications for OR51I1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B … Buck LB (Proceedings of the National Academy of Sciences of the United States of America 2004) 3 4 60
  2. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M … Hardison R (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 4 60
  3. Genetic determinants of haemolysis in sickle cell anaemia. (PMID: 23406172) Milton JN … Steinberg MH (British journal of haematology 2013) 3 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60

Products for OR51I1 Gene

Sources for OR51I1 Gene

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