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Aliases for OR51I1 Gene

Aliases for OR51I1 Gene

  • Olfactory Receptor, Family 51, Subfamily I, Member 1 2 3
  • Odorant Receptor HOR5beta11 3 4
  • Olfactory Receptor OR11-39 3 4
  • Olfactory Receptor 51I1 3
  • HOR5Beta11 3

External Ids for OR51I1 Gene

Summaries for OR51I1 Gene

Entrez Gene Summary for OR51I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51I1 Gene

OR51I1 (Olfactory Receptor, Family 51, Subfamily I, Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51I1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51I1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51I1 Gene

Genomics for OR51I1 Gene

Genomic Location for OR51I1 Gene

Start:
5,440,542 bp from pter
End:
5,441,553 bp from pter
Size:
1,012 bases
Orientation:
Minus strand

Genomic View for OR51I1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51I1 Gene

Regulatory Elements for OR51I1 Gene

Proteins for OR51I1 Gene

  • Protein details for OR51I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H343-O51I1_HUMAN
    Recommended name:
    Olfactory receptor 51I1
    Protein Accession:
    Q9H343
    Secondary Accessions:
    • B9EKW2
    • Q6IF33

    Protein attributes for OR51I1 Gene

    Size:
    314 amino acids
    Molecular mass:
    35484 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51I1 Gene

Proteomics data for OR51I1 Gene at MOPED

Post-translational modifications for OR51I1 Gene

No Post-translational modifications

Other Protein References for OR51I1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51I1 Gene

Domains for OR51I1 Gene

Gene Families for OR51I1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51I1 Gene

UniProtKB/Swiss-Prot:

O51I1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q9H343
genes like me logo Genes that share domains with OR51I1: view

Function for OR51I1 Gene

Molecular function for OR51I1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51I1 Gene

Localization for OR51I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51I1 Gene COMPARTMENTS Subcellular localization image for OR51I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

Pathways for OR51I1 Gene

genes like me logo Genes that share pathways with OR51I1: view

Pathways by source for OR51I1 Gene

Interacting Proteins for OR51I1 Gene

Gene Ontology (GO) - Biological Process for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

Transcripts for OR51I1 Gene

mRNA/cDNA for OR51I1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51I1 Gene

No ASD Table

Relevant External Links for OR51I1 Gene

GeneLoc Exon Structure for
OR51I1
ECgene alternative splicing isoforms for
OR51I1

Expression for OR51I1 Gene

mRNA expression in normal human tissues for OR51I1 Gene

mRNA differential expression in normal tissues according to GTEx for OR51I1 Gene

This gene is overexpressed in Testis (7.8).

SOURCE GeneReport for Unigene cluster for OR51I1 Gene Hs.553732

genes like me logo Genes that share expressions with OR51I1: view

Orthologs for OR51I1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51I1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466378 36
  • 99.15 (n)
  • 97.77 (a)
OR51I1 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OR51I1 36
  • 86.5 (n)
  • 86.82 (a)
OR51I1 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 60 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Olfr640 36
  • 83.71 (n)
  • 88.18 (a)
Olfr640 16
Olfr640 37
  • 88 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OR51I1 37
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 56 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr142 36
  • 85.2 (n)
  • 88.18 (a)
Species with no ortholog for OR51I1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51I1 Gene

ENSEMBL:
Gene Tree for OR51I1 (if available)
TreeFam:
Gene Tree for OR51I1 (if available)

Paralogs for OR51I1 Gene

Selected SIMAP similar genes for OR51I1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR51I1 Gene

genes like me logo Genes that share paralogs with OR51I1: view

Variants for OR51I1 Gene

Sequence variations from dbSNP and Humsavar for OR51I1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1498486 - 5,440,761(+) AAAGG(A/C)CAGCA reference, missense
rs1498487 -- 5,441,675(+) GCAAC(C/T)GGGTT upstream-variant-2KB
rs1498488 -- 5,442,308(+) CTTAA(A/C)CATTA upstream-variant-2KB
rs1498489 -- 5,442,873(+) ATCTT(C/T)TTGCT upstream-variant-2KB
rs4910793 -- 5,441,831(+) GGAAA(C/T)GCATC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51I1 Gene

Variant ID Type Subtype PubMed ID
nsv896931 CNV Loss 21882294
nsv832057 CNV Loss 17160897
essv3627 CNV CNV 17122850
dgv1025n71 CNV Loss 21882294
esv2664205 CNV Deletion 23128226
esv34391 CNV Loss 17911159

Relevant External Links for OR51I1 Gene

HapMap Linkage Disequilibrium report
OR51I1

Disorders for OR51I1 Gene

Relevant External Links for OR51I1

Genetic Association Database (GAD)
OR51I1
genes like me logo Genes that share disorders with OR51I1: view

No data available for UniProtKB/Swiss-Prot for OR51I1 Gene

Publications for OR51I1 Gene

  1. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. Genetic determinants of haemolysis in sickle cell anaemia. (PMID: 23406172) Milton J.N. … Steinberg M.H. (Br. J. Haematol. 2013) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR51I1 Gene

Sources for OR51I1 Gene

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