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Aliases for OR51I1 Gene

Aliases for OR51I1 Gene

  • Olfactory Receptor Family 51 Subfamily I Member 1 2 3 5
  • Olfactory Receptor, Family 51, Subfamily I, Member 1 2 3
  • Odorant Receptor HOR5beta11 3 4
  • Olfactory Receptor OR11-39 3 4
  • HOR5Beta11 3

External Ids for OR51I1 Gene

Previous GeneCards Identifiers for OR51I1 Gene

  • GC11U990514
  • GC11M005427
  • GC11M005409
  • GC11M005400
  • GC11M005418

Summaries for OR51I1 Gene

Entrez Gene Summary for OR51I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51I1 Gene

OR51I1 (Olfactory Receptor Family 51 Subfamily I Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51E1.

UniProtKB/Swiss-Prot for OR51I1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51I1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51I1 Gene

Genomics for OR51I1 Gene

Regulatory Elements for OR51I1 Gene

Enhancers for OR51I1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR51I1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR51I1 Gene

5,440,542 bp from pter
5,441,553 bp from pter
1,012 bases
Minus strand

Genomic View for OR51I1 Gene

Genes around OR51I1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51I1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51I1 Gene

Proteins for OR51I1 Gene

  • Protein details for OR51I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51I1
    Protein Accession:
    Secondary Accessions:
    • B9EKW2
    • Q6IF33

    Protein attributes for OR51I1 Gene

    314 amino acids
    Molecular mass:
    35484 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51I1 Gene

Proteomics data for OR51I1 Gene at MOPED

Post-translational modifications for OR51I1 Gene

No Post-translational modifications

Other Protein References for OR51I1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51I1 Gene

Domains & Families for OR51I1 Gene

Gene Families for OR51I1 Gene

Protein Domains for OR51I1 Gene

Suggested Antigen Peptide Sequences for OR51I1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51I1: view

Function for OR51I1 Gene

Molecular function for OR51I1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR51I1 Gene

GenomeRNAi human phenotypes for OR51I1:
genes like me logo Genes that share phenotypes with OR51I1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51I1 Gene

Localization for OR51I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR51I1 Gene COMPARTMENTS Subcellular localization image for OR51I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA,NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

Pathways & Interactions for OR51I1 Gene

genes like me logo Genes that share pathways with OR51I1: view

Pathways by source for OR51I1 Gene

Interacting Proteins for OR51I1 Gene

Gene Ontology (GO) - Biological Process for OR51I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 11121057
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 11121057
genes like me logo Genes that share ontologies with OR51I1: view

No data available for SIGNOR curated interactions for OR51I1 Gene

Drugs & Compounds for OR51I1 Gene

No Compound Related Data Available

Transcripts for OR51I1 Gene

mRNA/cDNA for OR51I1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51I1 Gene

No ASD Table

Relevant External Links for OR51I1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51I1 Gene

mRNA expression in normal human tissues for OR51I1 Gene

mRNA differential expression in normal tissues according to GTEx for OR51I1 Gene

This gene is overexpressed in Testis (x7.8).

SOURCE GeneReport for Unigene cluster for OR51I1 Gene Hs.553732

genes like me logo Genes that share expression patterns with OR51I1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR51I1 Gene

Orthologs for OR51I1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51I1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR51I1 35
  • 86.5 (n)
  • 86.82 (a)
OR51I1 36
  • 85 (a)
(Mus musculus)
Mammalia Olfr640 35
  • 83.71 (n)
  • 88.18 (a)
Olfr640 16
Olfr640 36
  • 88 (a)
(Pan troglodytes)
Mammalia LOC466378 35
  • 99.15 (n)
  • 97.77 (a)
OR51I1 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Olr142 35
  • 85.2 (n)
  • 88.18 (a)
(Canis familiaris)
Mammalia -- 36
  • 60 (a)
(Monodelphis domestica)
Mammalia OR51I1 36
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 56 (a)
Species with no ortholog for OR51I1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51I1 Gene

Gene Tree for OR51I1 (if available)
Gene Tree for OR51I1 (if available)

Paralogs for OR51I1 Gene

(410) SIMAP similar genes for OR51I1 Gene using alignment to 1 proteins: Pseudogenes for OR51I1 Gene

genes like me logo Genes that share paralogs with OR51I1: view

Variants for OR51I1 Gene

Sequence variations from dbSNP and Humsavar for OR51I1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
VAR_024142 -
VAR_034320 -
VAR_053328 -

Structural Variations from Database of Genomic Variants (DGV) for OR51I1 Gene

Variant ID Type Subtype PubMed ID
nsv896931 CNV Loss 21882294
nsv832057 CNV Loss 17160897
essv3627 CNV CNV 17122850
dgv1025n71 CNV Loss 21882294
esv2664205 CNV Deletion 23128226
esv34391 CNV Loss 17911159

Variation tolerance for OR51I1 Gene

Residual Variation Intolerance Score: 95.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 17.97; 98.40% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR51I1 Gene

Disorders for OR51I1 Gene

Relevant External Links for OR51I1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR51I1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51I1 Gene

Publications for OR51I1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Genetic determinants of haemolysis in sickle cell anaemia. (PMID: 23406172) Milton J.N. … Steinberg M.H. (Br. J. Haematol. 2013) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. (PMID: 11121057) Bulger M. … Hardison R. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  5. Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. (PMID: 10220430) Bulger M. … Groudine M. (Proc. Natl. Acad. Sci. U.S.A. 1999) 3

Products for OR51I1 Gene

Sources for OR51I1 Gene