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Aliases for OR51G2 Gene

Aliases for OR51G2 Gene

  • Olfactory Receptor, Family 51, Subfamily G, Member 2 2 3
  • Olfactory Receptor OR11-28 3 4
  • Olfactory Receptor 51G2 3
  • OR11-28 3

External Ids for OR51G2 Gene

Previous GeneCards Identifiers for OR51G2 Gene

  • GC11U990516
  • GC11M004892

Summaries for OR51G2 Gene

Entrez Gene Summary for OR51G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51G2 Gene

OR51G2 (Olfactory Receptor, Family 51, Subfamily G, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR51G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51G2 Gene

Genomics for OR51G2 Gene

Regulatory Elements for OR51G2 Gene

Genomic Location for OR51G2 Gene

Start:
4,914,719 bp from pter
End:
4,915,663 bp from pter
Size:
945 bases
Orientation:
Minus strand

Genomic View for OR51G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51G2 Gene

Proteins for OR51G2 Gene

  • Protein details for OR51G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGK0-O51G2_HUMAN
    Recommended name:
    Olfactory receptor 51G2
    Protein Accession:
    Q8NGK0
    Secondary Accessions:
    • Q6IFH7

    Protein attributes for OR51G2 Gene

    Size:
    314 amino acids
    Molecular mass:
    35012 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51G2 Gene

Proteomics data for OR51G2 Gene at MOPED

Post-translational modifications for OR51G2 Gene

  • Glycosylation at Asn8
  • Modification sites at PhosphoSitePlus

Other Protein References for OR51G2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51G2 Gene

Domains for OR51G2 Gene

Gene Families for OR51G2 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51G2 Gene

Suggested Antigen Peptide Sequences for OR51G2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGK0

UniProtKB/Swiss-Prot:

O51G2_HUMAN :
  • Q8NGK0
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51G2: view

Function for OR51G2 Gene

Molecular function for OR51G2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51G2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51G2 Gene

Localization for OR51G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51G2 Gene COMPARTMENTS Subcellular localization image for OR51G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51G2: view

Pathways for OR51G2 Gene

genes like me logo Genes that share pathways with OR51G2: view

Pathways by source for OR51G2 Gene

Interacting Proteins for OR51G2 Gene

Gene Ontology (GO) - Biological Process for OR51G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51G2: view

Transcripts for OR51G2 Gene

mRNA/cDNA for OR51G2 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR51G2 Gene

Olfactory receptor, family 51, subfamily G, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR51G2 Gene

No ASD Table

Relevant External Links for OR51G2 Gene

GeneLoc Exon Structure for
OR51G2
ECgene alternative splicing isoforms for
OR51G2

Expression for OR51G2 Gene

mRNA expression in normal human tissues for OR51G2 Gene

SOURCE GeneReport for Unigene cluster for OR51G2 Gene Hs.542302

genes like me logo Genes that share expressions with OR51G2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR51G2 Gene

Orthologs for OR51G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51G2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 54 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 90 (a)
OneToMany
-- 36
  • 87 (a)
OneToMany
LOC508595 35
  • 88.14 (n)
  • 89.74 (a)
dog
(Canis familiaris)
Mammalia OR51G2 35
  • 89.71 (n)
  • 93.29 (a)
OR51G2 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr577 35
  • 85.62 (n)
  • 92.64 (a)
Olfr577 16
Olfr577 36
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr69 35
  • 86.18 (n)
  • 92.64 (a)
Species with no ortholog for OR51G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51G2 Gene

ENSEMBL:
Gene Tree for OR51G2 (if available)
TreeFam:
Gene Tree for OR51G2 (if available)

Paralogs for OR51G2 Gene

Selected SIMAP similar genes for OR51G2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR51G2 Gene

genes like me logo Genes that share paralogs with OR51G2: view

Variants for OR51G2 Gene

Sequence variations from dbSNP and Humsavar for OR51G2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs919900 -- 4,915,908(+) TGAGC(C/T)AAACT upstream-variant-2KB
rs956917 -- 4,916,222(+) ggcag(G/T)ggctg upstream-variant-2KB
rs2570580 -- 4,917,122(+) GAACA(C/T)GCCCC upstream-variant-2KB
rs2595976 -- 4,917,183(-) TTAGC(G/T)AAATA upstream-variant-2KB
rs2595977 -- 4,916,089(-) CGCCC(A/G)CCTCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51G2 Gene

Variant ID Type Subtype PubMed ID
dgv340e1 CNV Complex 17122850
nsv507580 CNV Insertion 20534489

Relevant External Links for OR51G2 Gene

HapMap Linkage Disequilibrium report
OR51G2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR51G2 Gene

Disorders for OR51G2 Gene

Relevant External Links for OR51G2

Genetic Association Database (GAD)
OR51G2
genes like me logo Genes that share disorders with OR51G2: view

No data available for UniProtKB/Swiss-Prot for OR51G2 Gene

Publications for OR51G2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 48
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Natural selection on the olfactory receptor gene family in humans and chimpanzees. (PMID: 12908129) Gilad Y. … Paabo S. (Am. J. Hum. Genet. 2003) 3

Products for OR51G2 Gene

Sources for OR51G2 Gene

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