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Aliases for OR51G1 Gene

Aliases for OR51G1 Gene

  • Olfactory Receptor, Family 51, Subfamily G, Member 1 (Gene/Pseudogene) 2 3
  • Olfactory Receptor OR11-29 3 4
  • Olfactory Receptor 51G3 3 4
  • OR51G3P 3 4
  • Olfactory Receptor 51G1 3
  • OR11-29 3

External Ids for OR51G1 Gene

Previous Symbols for OR51G1 Gene

  • OR51G3P

Summaries for OR51G1 Gene

Entrez Gene Summary for OR51G1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51G1 Gene

OR51G1 (Olfactory Receptor, Family 51, Subfamily G, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51G1 Gene

  • Odorant receptor.

Gene Wiki entry for OR51G1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51G1 Gene

Genomics for OR51G1 Gene

Genomic Location for OR51G1 Gene

Start:
4,923,374 bp from pter
End:
4,924,339 bp from pter
Size:
966 bases
Orientation:
Minus strand

Genomic View for OR51G1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51G1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51G1 Gene

Regulatory Elements for OR51G1 Gene

Proteins for OR51G1 Gene

  • Protein details for OR51G1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGK1-O51G1_HUMAN
    Recommended name:
    Olfactory receptor 51G1
    Protein Accession:
    Q8NGK1
    Secondary Accessions:
    • B9EGW8
    • Q6IFH6

    Protein attributes for OR51G1 Gene

    Size:
    321 amino acids
    Molecular mass:
    36290 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51G1 Gene

Proteomics data for OR51G1 Gene at MOPED

Post-translational modifications for OR51G1 Gene

Other Protein References for OR51G1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51G1 Gene

Domains for OR51G1 Gene

Gene Families for OR51G1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51G1 Gene

UniProtKB/Swiss-Prot:

O51G1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGK1
genes like me logo Genes that share domains with OR51G1: view

Function for OR51G1 Gene

Molecular function for OR51G1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51G1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51G1 Gene

Localization for OR51G1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51G1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51G1 Gene COMPARTMENTS Subcellular localization image for OR51G1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51G1: view

Pathways for OR51G1 Gene

genes like me logo Genes that share pathways with OR51G1: view

Pathways by source for OR51G1 Gene

Interacting Proteins for OR51G1 Gene

Gene Ontology (GO) - Biological Process for OR51G1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51G1: view

Transcripts for OR51G1 Gene

mRNA/cDNA for OR51G1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51G1 Gene

No ASD Table

Relevant External Links for OR51G1 Gene

GeneLoc Exon Structure for
OR51G1
ECgene alternative splicing isoforms for
OR51G1

Expression for OR51G1 Gene

mRNA expression in normal human tissues for OR51G1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR51G1 Gene

SOURCE GeneReport for Unigene cluster for OR51G1 Gene Hs.554541

genes like me logo Genes that share expressions with OR51G1: view

Orthologs for OR51G1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51G1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC748426 36
  • 99.07 (n)
  • 97.82 (a)
OR51G1 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC504551 36
  • 87.44 (n)
  • 89.1 (a)
OR51G1 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OR51G1 36
  • 87.32 (n)
  • 89.62 (a)
OR51G1 37
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr578 36
  • 84.56 (n)
  • 89.14 (a)
Olfr578 16
Olfr578 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 49 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Olr70 36
  • 83.49 (n)
  • 87.54 (a)
Species with no ortholog for OR51G1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51G1 Gene

ENSEMBL:
Gene Tree for OR51G1 (if available)
TreeFam:
Gene Tree for OR51G1 (if available)

Paralogs for OR51G1 Gene

Selected SIMAP similar genes for OR51G1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR51G1: view

Variants for OR51G1 Gene

Sequence variations from dbSNP and Humsavar for OR51G1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1378739 - 4,923,966(-) CCGCT(A/C)CGTGG reference, missense
rs1469750 -- 4,926,083(+) GCACA(C/T)TGAAG upstream-variant-2KB
rs2570587 -- 4,923,085(-) CAATT(C/T)TCAAT downstream-variant-500B
rs7947422 -- 4,925,320(+) CATTA(C/G)AAGAG upstream-variant-2KB
rs7947674 -- 4,925,508(+) GGAGA(C/G)GGTCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR51G1 Gene

Variant ID Type Subtype PubMed ID
dgv340e1 CNV Complex 17122850

Relevant External Links for OR51G1 Gene

HapMap Linkage Disequilibrium report
OR51G1
Human Gene Mutation Database (HGMD)
OR51G1

Disorders for OR51G1 Gene

Relevant External Links for OR51G1

Genetic Association Database (GAD)
OR51G1
Human Genome Epidemiology (HuGE) Navigator
OR51G1
genes like me logo Genes that share disorders with OR51G1: view

No data available for UniProtKB/Swiss-Prot for OR51G1 Gene

Publications for OR51G1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR51G1 Gene

Sources for OR51G1 Gene

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