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Aliases for OR51F1 Gene

Aliases for OR51F1 Gene

  • Olfactory Receptor, Family 51, Subfamily F, Member 1 (Gene/Pseudogene) 2 3
  • OR51F1P 3 4
  • Olfactory Receptor, Family 51, Subfamily F, Member 1 Pseudogene 3
  • Olfactory Receptor OR11-21 Pseudogene 3
  • Olfactory Receptor 51F1 3
  • OR11-21 3

External Ids for OR51F1 Gene

Previous Symbols for OR51F1 Gene

  • OR51F1P

Summaries for OR51F1 Gene

Entrez Gene Summary for OR51F1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR51F1 Gene

OR51F1 (Olfactory Receptor, Family 51, Subfamily F, Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51I2.

UniProtKB/Swiss-Prot for OR51F1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51F1 Gene

Genomics for OR51F1 Gene

Genomic Location for OR51F1 Gene

Start:
4,768,979 bp from pter
End:
4,769,917 bp from pter
Size:
939 bases
Orientation:
Minus strand

Genomic View for OR51F1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR51F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51F1 Gene

Regulatory Elements for OR51F1 Gene

Proteins for OR51F1 Gene

  • Protein details for OR51F1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGY5-O51F1_HUMAN
    Recommended name:
    Olfactory receptor 51F1
    Protein Accession:
    A6NGY5
    Secondary Accessions:

    Protein attributes for OR51F1 Gene

    Size:
    319 amino acids
    Molecular mass:
    35849 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51F1 Gene

Proteomics data for OR51F1 Gene at MOPED

Post-translational modifications for OR51F1 Gene

No Post-translational modifications

Other Protein References for OR51F1 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR51F1 Gene

Domains for OR51F1 Gene

Gene Families for OR51F1 Gene

HGNC:
  • OR51 :GPCR / Class A : Olfactory receptors

Protein Domains for OR51F1 Gene

UniProtKB/Swiss-Prot:

O51F1_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • A6NGY5
genes like me logo Genes that share domains with OR51F1: view

Function for OR51F1 Gene

Molecular function for OR51F1 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR51F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR51F1: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR51F1 Gene

Localization for OR51F1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51F1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR51F1 Gene COMPARTMENTS Subcellular localization image for OR51F1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51F1: view

Pathways for OR51F1 Gene

genes like me logo Genes that share pathways with OR51F1: view

Pathways by source for OR51F1 Gene

Interacting Proteins for OR51F1 Gene

Gene Ontology (GO) - Biological Process for OR51F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51F1: view

Transcripts for OR51F1 Gene

mRNA/cDNA for OR51F1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51F1 Gene

No ASD Table

Relevant External Links for OR51F1 Gene

GeneLoc Exon Structure for
OR51F1
ECgene alternative splicing isoforms for
OR51F1

Expression for OR51F1 Gene

mRNA expression in normal human tissues for OR51F1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR51F1 Gene

SOURCE GeneReport for Unigene cluster for OR51F1 Gene Hs.553659

genes like me logo Genes that share expressions with OR51F1: view

Orthologs for OR51F1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51F1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466349 36
  • 98.18 (n)
  • 97.44 (a)
OR51F1 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 80 (a)
OneToMany
-- 37
  • 80 (a)
OneToMany
LOC507882 36
  • 85.15 (n)
  • 82.05 (a)
dog
(Canis familiaris)
Mammalia LOC100684107 36
  • 84.96 (n)
  • 82.47 (a)
OR51F1 37
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr566 37
  • 81 (a)
OneToMany
Olfr583 37
  • 76 (a)
OneToMany
Olfr585 16
Olfr585 37
  • 77 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 71 (a)
OneToMany
-- 37
  • 74 (a)
OneToMany
-- 37
  • 69 (a)
OneToMany
-- 37
  • 66 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia LOC684170 36
  • 82.32 (n)
  • 79.42 (a)
Species with no ortholog for OR51F1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51F1 Gene

ENSEMBL:
Gene Tree for OR51F1 (if available)
TreeFam:
Gene Tree for OR51F1 (if available)

Paralogs for OR51F1 Gene

Selected SIMAP similar genes for OR51F1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR51F1: view

Variants for OR51F1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR51F1 Gene

A6NGY5-O51F1_HUMAN
A single nucleotide deletion at position Arg-92 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The deletion is more frequent in African-Americans than in non-Africans

Sequence variations from dbSNP and Humsavar for OR51F1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1030723 - 4,769,241(-) TCGCT(C/T)TGTCC reference, missense
rs1030724 -- 4,769,180(-) TCCCA(C/T)GTGGG synonymous-codon, reference
rs1030725 -- 4,769,078(-) GCTAA(C/T)GTATA synonymous-codon, reference
rs1030726 - 4,769,038(-) TCATC(G/T)ACAGT reference, missense
rs1030727 -- 4,768,840(-) TTGTA(C/T)ATTTG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OR51F1 Gene

Variant ID Type Subtype PubMed ID
nsv896911 CNV Gain 21882294
nsv896915 CNV Gain 21882294
nsv832056 CNV Gain 17160897
nsv896916 CNV Loss 21882294
esv29053 CNV Loss 19812545

Relevant External Links for OR51F1 Gene

HapMap Linkage Disequilibrium report
OR51F1

Disorders for OR51F1 Gene

No disorders were found for OR51F1 Gene.

No data available for UniProtKB/Swiss-Prot for OR51F1 Gene

Publications for OR51F1 Gene

  1. Population differences in the human functional olfactory repertoire. (PMID: 12644552) Gilad Y. … Lancet D. (Mol. Biol. Evol. 2003) 3
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  3. Imputation-based meta-analysis of severe malaria in three African populations. (PMID: 23717212) Band G. … . (PLoS Genet. 2013) 3
  4. Different noses for different people. (PMID: 12730696) Menashe I. … Gilad Y. (Nat. Genet. 2003) 4
  5. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR51F1 Gene

  • antibodies-online peptides for OR51F1
  • antibodies-online antibodies for OR51F1
  • antibodies-online kits for OR51F1

Sources for OR51F1 Gene

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