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Aliases for OR51F1 Gene

Aliases for OR51F1 Gene

  • Olfactory Receptor Family 51 Subfamily F Member 1 (Gene/Pseudogene) 2 3 5
  • OR51F1P 3 4
  • Olfactory Receptor, Family 51, Subfamily F, Member 1 (Gene/Pseudogene) 2
  • Olfactory Receptor, Family 51, Subfamily F, Member 1 Pseudogene 3
  • Olfactory Receptor OR11-21 Pseudogene 3
  • OR11-21 3

External Ids for OR51F1 Gene

Previous HGNC Symbols for OR51F1 Gene

  • OR51F1P

Previous GeneCards Identifiers for OR51F1 Gene

  • GC11M004756
  • GC11M004746

Summaries for OR51F1 Gene

Entrez Gene Summary for OR51F1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]

GeneCards Summary for OR51F1 Gene

OR51F1 (Olfactory Receptor Family 51 Subfamily F Member 1 (Gene/Pseudogene)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51E1.

UniProtKB/Swiss-Prot for OR51F1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR51F1 Gene

Genomics for OR51F1 Gene

Regulatory Elements for OR51F1 Gene

Enhancers for OR51F1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR51F1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR51F1 Gene

4,768,979 bp from pter
4,769,917 bp from pter
939 bases
Minus strand

Genomic View for OR51F1 Gene

Genes around OR51F1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR51F1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR51F1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR51F1 Gene

Proteins for OR51F1 Gene

  • Protein details for OR51F1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 51F1
    Protein Accession:

    Protein attributes for OR51F1 Gene

    319 amino acids
    Molecular mass:
    35849 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR51F1 Gene

Proteomics data for OR51F1 Gene at MOPED

Post-translational modifications for OR51F1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OR51F1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR51F1 Gene

Domains & Families for OR51F1 Gene

Gene Families for OR51F1 Gene

Protein Domains for OR51F1 Gene

Suggested Antigen Peptide Sequences for OR51F1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR51F1: view

Function for OR51F1 Gene

Molecular function for OR51F1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Phenotypes for OR51F1 Gene

genes like me logo Genes that share phenotypes with OR51F1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR51F1 Gene

Localization for OR51F1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR51F1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR51F1 Gene COMPARTMENTS Subcellular localization image for OR51F1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR51F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR51F1: view

Pathways & Interactions for OR51F1 Gene

genes like me logo Genes that share pathways with OR51F1: view

Pathways by source for OR51F1 Gene

Interacting Proteins for OR51F1 Gene

Gene Ontology (GO) - Biological Process for OR51F1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR51F1: view

No data available for SIGNOR curated interactions for OR51F1 Gene

Drugs & Compounds for OR51F1 Gene

No Compound Related Data Available

Transcripts for OR51F1 Gene

mRNA/cDNA for OR51F1 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR51F1 Gene

No ASD Table

Relevant External Links for OR51F1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR51F1 Gene

mRNA expression in normal human tissues for OR51F1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR51F1 Gene

SOURCE GeneReport for Unigene cluster for OR51F1 Gene Hs.553659

genes like me logo Genes that share expression patterns with OR51F1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR51F1 Gene

Orthologs for OR51F1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR51F1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC507882 35
  • 85.15 (n)
  • 82.05 (a)
-- 36
  • 80 (a)
-- 36
  • 80 (a)
(Canis familiaris)
Mammalia LOC100684107 35
  • 84.96 (n)
  • 82.47 (a)
OR51F1 36
  • 80 (a)
(Pan troglodytes)
Mammalia LOC466349 35
  • 98.18 (n)
  • 97.44 (a)
OR51F1 36
  • 95 (a)
(Rattus norvegicus)
Mammalia LOC684170 35
  • 82.32 (n)
  • 79.42 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 71 (a)
-- 36
  • 74 (a)
-- 36
  • 69 (a)
-- 36
  • 66 (a)
(Mus musculus)
Mammalia Olfr566 36
  • 81 (a)
Olfr583 36
  • 76 (a)
Olfr585 36
  • 77 (a)
Species with no ortholog for OR51F1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR51F1 Gene

Gene Tree for OR51F1 (if available)
Gene Tree for OR51F1 (if available)

Paralogs for OR51F1 Gene

(358) SIMAP similar genes for OR51F1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with OR51F1: view

Variants for OR51F1 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for OR51F1 Gene

A single nucleotide deletion at position Arg-92 in the gene coding for this protein is responsible for functional diversity thus producing a pseudogene. The deletion is more frequent in African-Americans than in non-Africans.

Sequence variations from dbSNP and Humsavar for OR51F1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs17324812 - 4,769,881(+) GAAGG(C/T)TGGAA reference, missense
rs11033801 - 4,769,721(+) GCATG(A/G)AGAGG reference, missense
rs11033800 - 4,769,718(+) ATAGC(A/C)TGGAG reference, missense
rs11033793 - 4,769,244(+) CAGAG(C/T)GAATA reference, missense
rs1030726 - 4,769,038(-) TCATC(A/G/T)ACAGT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for OR51F1 Gene

Variant ID Type Subtype PubMed ID
nsv896911 CNV Gain 21882294
nsv896915 CNV Gain 21882294
nsv832056 CNV Gain 17160897
nsv896916 CNV Loss 21882294
esv29053 CNV Loss 19812545

Variation tolerance for OR51F1 Gene

Residual Variation Intolerance Score: 95.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 21.33; 99.26% of all genes are more intolerant (likely to be disease-causing)

No data available for Relevant External Links for OR51F1 Gene

Disorders for OR51F1 Gene

Relevant External Links for OR51F1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR51F1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR51F1 Gene

Publications for OR51F1 Gene

  1. Imputation-based meta-analysis of severe malaria in three African populations. (PMID: 23717212) Band G. … . (PLoS Genet. 2013) 3 67
  2. Personal receptor repertoires: olfaction as a model. (PMID: 22908908) Olender T. … Lancet D. (BMC Genomics 2012) 3
  3. A probabilistic classifier for olfactory receptor pseudogenes. (PMID: 16939646) Menashe I. … Lancet D. (BMC Bioinformatics 2006) 3
  4. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  5. Population differences in the human functional olfactory repertoire. (PMID: 12644552) Gilad Y. … Lancet D. (Mol. Biol. Evol. 2003) 3

Products for OR51F1 Gene

Sources for OR51F1 Gene