OR51E2 Gene

Aliases
for OR51E2 gene

Previous GC identifers: GC11M005267 GC11M005003 GC11M004660 GC11M004665 GC11M004657

Summaries
for OR51E2 gene

Genomic Views
for OR51E2 gene

RefSeq DNA sequence:

NC_000011.9  NC_018922.1  NT_009237.18  

SwitchGear Promoter luciferase reporter plasmid: OR51E2 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR51E2

OR51E2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M004701:  view genomic region     (about GC identifiers)

Proteins
for OR51E2 gene

Explore the universe of human proteins at neXtProt for OR51E2: NX_Q9H255

HORDE protein sequence for OR51E2
OR51E2 Protein expression data from MOPED and PaxDb:    About this image 

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: OR51E2 OriGene Protein Over-expression Lysate: OR51E2 OriGene Custom Protein Services for OR51E2
	GenScript Custom Purified and Recombinant Proteins Services for OR51E2
	Novus Biologicals OR51E2 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for OR51E2

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	Browse OriGene Antibodies OriGene Custom Antibody Services for OR51E2
	GenScript Custom Superior Antibodies Services for OR51E2
	Novus Biologicals OR51E2 Antibodies
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	Uscn Antibodies for OR51E2
	ThermoFisher Antibodies for OR51E2

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for OR51E2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for OR51E2

Protein Domains /
Families
for OR51E2 gene

ProtoNet protein and cluster: Q9H255

Function
for OR51E2 gene

miRNA Products:		OriGene 3'-UTR Clone: OR51E2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OR51E2
		8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate OR51E2 (see all 10):
		hsa-miR-3164 hsa-miR-875-3p hsa-miR-1271 hsa-miR-4282 hsa-miR-410 hsa-miR-570 hsa-miR-514 hsa-miR-3915
		SwitchGear 3'UTR luciferase reporter plasmid: OR51E2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OR51E2 (see all 4) OriGene shRNA RFP: OR51E2 OriGene siRNA: OR51E2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR51E2

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for OR51E2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OR51E2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OR51E2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OR51E2 (NM_030774)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51E2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for OR51E2
		Search LifeMap BioReagents cell lines for OR51E2

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E2

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

(inferred from 2 alleles) (MGI details for Olfr78)

Pathways & Interactions
for OR51E2 gene

	Super-pathway	contained gene-specific pathways
1	Signaling by GPCR	Signaling by GPCR 1.00 Signal Transduction 0.56 GPCR downstream signaling 0.89
2	Olfactory transduction	Olfactory transduction 1.00 Olfactory Signaling Pathway 0.77

4        Reactome Pathways for OR51E2

	GPCR downstream signaling
	Olfactory Signaling Pathway
	Signal Transduction
	Signaling by GPCR

1         Kegg Pathway  (Kegg details for OR51E2)

Olfactory transduction

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for OR51E2 gene

Transcripts
for OR51E2 gene

Expression
for OR51E2 gene

OR51E2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTATTGTCTG

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	TestisSeminiferous TubulesSertoli cells			Testis
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OR51E2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OR51E2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR51E2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR51E2

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E2

Orthologs
for OR51E2 gene

Paralogs
for OR51E2 gene

Paralogs for OR51E2 gene

OR51D1²  OR51T1²  OR51F5P²  OR51F2²  OR51G2²  OR51A7²  OR51A2²  OR51F1²  

OR51L1²  OR51C1P²  OR51A4²  OR51I1²  OR51G1²  OR51H1P²  OR51I2²  OR51E1²  

18/421 SIMAP similar genes for OR51E2 using alignment to 2 protein entries:     O51E2_HUMAN (see all proteins) (see all similar genes):

OR51E1    OR51D1    OR51G2    OR52K1    OR52K2    OR51A4

OR51A2    OR51G1    OR51A7    OR51F2    OR52J3    OR52M1

OR51B6    OR51H1P    OR51L1    OR51V1    OR52D1    OR52L1

OR51E2 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for OR51E2
PGOHUM00000257871

Genomic Variants
for OR51E2 gene

10/390 NCBI SNPs in OR51E2 are shown (see all 390)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1424865611,2		--	4701486(+)	GGTACA/GGAGCA	1	--	ut31		0	--	--	--	--
rs16851,2	C,F,O,H,	--	4701510(+)	AGACAT/CGATCA	1	--	ut31 ese3		15		MN NA NS EA	1294
rs1471729701,2		--	4701585(+)	GATCAC/TGAAAG	1	--	ut31		0	--	--	--	--
rs22921571,2	C,F,O,H,	--	4701586(-)	CCTTTC/TGTGAT	1	--	ut31		14		EA NA NS WA	2468
rs1403666241,2		--	4701625(+)	TGTTGC/TCCACA	1	--	ut31		0	--	--	--	--
rs1859057921,2		--	4701737(+)	GATGTA/TACACA	1	--	ut31		0	--	--	--	--
rs1455942661,2		--	4701825(+)	AAGCCA/GTGTGA	1	--	ut31		0	--	--	--	--
rs1899750101,2		--	4701894(+)	ATGGTA/GCCTAC	1	--	ut31		0	--	--	--	--
rs1812699671,2		--	4701912(+)	AGTTAC/TGAAGA	1	--	ut31		0	--	--	--	--
rs71118831,2	C,F,A,H,	--	4701913(+)	GTTACG/AAAGAA	1	--	ut31 ese3		18		NS EA NA WA	2342

HapMap Linkage Disequilibrium report for OR51E2 ( 4702982 - 4703941 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for OR51E2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OR51E2

DNA2.0 Custom Variant and Variant Library Synthesis for OR51E2

Disorders / Diseases
for OR51E2 gene

3 diseases for OR51E2

2 Novoseek disease relationships for OR51E2 gene    About this table

Publications
for OR51E2 gene

PubMed articles for OR51E2 gene, integrated from 9 sources (see all 15): (articles sorted by number of sources associating them with OR51E2)

Utopia: connect your pdf to the dynamic world of online information

1. PSGR, a novel prostate-specific gene with homology to a G protein- coupled receptor, is overexpressed in prostate cancer. (PubMed id 11118034)^{1, 2, 3, 9} Xu L.L.... Srivastava S. (2000)
2. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. (PubMed id 16491480)^{1, 2, 9} Wang J....Ittmann M. (2006)
3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
4. The human olfactory receptor gene family. (PubMed id 14983052)^{1, 2} Malnic B.... Buck L.B. (2004)
5. Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species. (PubMed id 11707321)^{1, 2} Yuan T.T....Kretschmer P.J. (2001)
6. Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors. (PubMed id 16149059)^{1, 9} Weng J....Liu M. (2005)
7. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. (PubMed id 15499628)^{1, 9} Weng J....Liu M. (2005)
8. Activation of an olfactory receptor inhibits prolifer ation of prostate cancer cells. (PubMed id 19389702)^{1, 9} Neuhaus E.M....Hatt H. (2009)
9. Identification of a prostate-specific G-protein coupled receptor in prostate cancer. (PubMed id 11593396)^{1, 9} Xia C....Liu M. (2001)
10. Quantitative expression profile of PSGR in prostate cancer. (PubMed id 16231015)¹ Xu L.L....Srivastava S. (2006)

External Searches for OR51E2 gene

Genome Databases showing OR51E2 gene

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Products
for OR51E2 gene