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OR51E2 Gene

protein-coding   GIFtS: 55
GCID: GC11M004701

Olfactory Receptor, Family 51, Subfamily E, Member 2

  See OR51E2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Olfactory Receptor, Family 51, Subfamily E, Member 21 2     OR52A22
PSGR2 3 5     Olfactory Receptor 51E22
Olfactory Receptor OR11-162 3     Olfactory Receptor, Family 51, Subfamily E, Member 3 Pseudogene2
Prostate-Specific G-Protein Coupled Receptor2 3     Olfactory Receptor, Family 52, Subfamily A, Member 22
HPRAJ2 3     Prostate Specific G-Protein Coupled Receptor2
OR51E3P2     

External Ids:    HGNC: 151951   Entrez Gene: 812852   Ensembl: ENSG000001673327   OMIM: 6112685   UniProtKB: Q9H2553   

Export aliases for OR51E2 gene to outside databases

Previous GC identifers: GC11M005267 GC11M005003 GC11M004660 GC11M004665 GC11M004657


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OR51E2 Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for OR51E2 Gene:
OR51E2 (olfactory receptor, family 51, subfamily E, member 2) is a protein-coding gene. Diseases associated with OR51E2 include prostate cancer. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51M1.

UniProtKB/Swiss-Prot: O51E2_HUMAN, Q9H255
Function: Odorant receptor (Potential)

Gene Wiki entry for OR51E2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the OR51E2 gene promoter:
         STAT1   STAT4   STAT1beta   CUTL1   STAT1alpha   FOXJ2 (long isoform)   STAT2   STAT3   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOR51E2 promoter sequence
   Search Chromatin IP Primers for OR51E2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR51E2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15

OR51E2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OR51E2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M004701:  view genomic region     (about GC identifiers)

Start:
4,702,982 bp from pter      End:
4,703,941 bp from pter
Size:
960 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: O51E2_HUMAN, Q9H255 (See protein sequence)
Recommended Name: Olfactory receptor 51E2  
Size: 320 amino acids; 35493 Da
Secondary accessions: B2RA63 Q6IF94

Explore the universe of human proteins at neXtProt for OR51E2: NX_Q9H255

Explore proteomics data for OR51E2 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn5
  • HORDE protein sequence for OR51E2

    See OR51E2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_110401.1  
    ENSEMBL proteins: 
     ENSP00000380153   ENSP00000432644  
    Reactome Protein details: Q9H255

    OR51E2 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OR51: GPCR / Class A : Olfactory receptors

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000725 Olfact_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q9H255

    ProtoNet protein and cluster: Q9H255

    1 Blocks protein domain: IPB000725 Olfactory receptor signature

    UniProtKB/Swiss-Prot: O51E2_HUMAN, Q9H255
    Similarity: Belongs to the G-protein coupled receptor 1 family


    Find genes that share domains with OR51E2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: O51E2_HUMAN, Q9H255
    Function: Odorant receptor (Potential)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0004984olfactory receptor activity IEA--
         
    Find genes that share ontologies with OR51E2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for OR51E2:
     Decreased viability  Increased gamma-H2AX phosphory 

         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Olfr78):
     craniofacial  nervous system  no phenotypic analysis  respiratory system  taste/olfaction 

    Find genes that share phenotypes with OR51E2           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Olfr78tm1Mom for OR51E2

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OR51E2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OR51E2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OR51E2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OR51E2

    miRNA
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    miRTarBase miRNAs that target OR51E2:
    hsa-mir-1303 (MIRT035900)

    Block miRNA regulation of human, mouse, rat OR51E2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OR51E2 (see all 10):
    hsa-miR-3164 hsa-miR-875-3p hsa-miR-1271 hsa-miR-4282 hsa-miR-410 hsa-miR-570 hsa-miR-514 hsa-miR-3915
    SwitchGear 3'UTR luciferase reporter plasmidOR51E2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat OR51E2

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    Addgene plasmids for OR51E2 

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    eBioscience FlowRNA Probe Sets ( VA1-10604) for OR51E2 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    O51E2_HUMAN, Q9H255: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with OR51E2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for OR51E2 About    
    See pathways by source

    SuperPathContained pathways About
    1Olfactory Signaling Pathway
    Olfactory Signaling Pathway0.82
    Olfactory transduction0.82
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90


    Find genes that share SuperPaths with OR51E2           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for OR51E2
        Olfactory Signaling Pathway


    1 Kegg Pathway  (Kegg details for OR51E2):
        Olfactory transduction

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OR51E2
    Interactions:

        GeneGlobe Interaction Network for OR51E2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for OR51E2 (ENSP000003801534) via UniProtKB, MINT, STRING, and/or I2D (see all 273)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OR52E6ENSP000003288784STRING: ENSP00000369279 STRING: ENSP00000328878
    OR10A3ENSP000003539884STRING: ENSP00000353988
    OR10A7ENSP000003267184STRING: ENSP00000326718
    OR10J5ENSP000003344414STRING: ENSP00000334441
    OR1D2ENSP000003275854STRING: ENSP00000327585
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007608sensory perception of smell ----
    GO:0050911detection of chemical stimulus involved in sensory perception of smell ----

    Find genes that share ontologies with OR51E2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OR51E2 (O51E2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OR51E2 gene: 
    NM_030774.3  

    Unigene Clusters for OR51E2:

    Olfactory receptor, family 51, subfamily E, member 2
    Hs.501758  [show with all ESTs], Hs.606330
    Unigene Representative Sequences: AY033942, BC020768
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396950(uc001lzk.2) ENST00000532598
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate OR51E2 (see all 10):
    hsa-miR-3164 hsa-miR-875-3p hsa-miR-1271 hsa-miR-4282 hsa-miR-410 hsa-miR-570 hsa-miR-514 hsa-miR-3915
    SwitchGear 3'UTR luciferase reporter plasmidOR51E2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: BC020768.1 

    2 DOTS entries:

    DT.95263462  DT.97823575 

    Selected AceView cDNA sequences (see all 28):

    AA313094 AA298489 CN836105 BX096699 AW263421 AY033942 AI432462 AA135870 
    NM_030774 AF369708 AA298464 CN836310 BC020768 AI805082 BF372204 AA298471 
    CN841354 BG150058 AA137165 AA031604 BF677705 BF674962 AA298475 AA031360 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OR51E2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTATTGTCTG
    OR51E2 Expression
    About this image


    OR51E2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             Sertoli cells Seminiferous Tubules
     
     Prostate (Endocrine System)
    OR51E2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OR51E2 Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.501758 Hs.606330

    UniProtKB/Swiss-Prot: O51E2_HUMAN, Q9H255
    Tissue specificity: Exclusively expressed in the prostate. Up-regulated in prostate cancers

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for OR51E2 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfr781 , 5 olfactory receptor 781, 5 86.94(n)1
    93.1(a)1
      7 (54.83 cM)5
    1706391  NM_130866.41  NP_570936.11 
     1027407215 
    lizard
    (Anolis carolinensis)
    Reptilia OR51E26
    olfactory receptor, family 51, subfamily E, member...
    52(a)
    1 ↔ 1
    GL344018.1(10407-11384)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia or51e11 olfactory receptor, family 51, subfamily E, member more 62.84(n)
    57.7(a)
      100145326  NM_001126801.1  NP_001120273.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01018874.16
    or112-16
    Uncharacterized protein
    odorant receptor, family A, subfamily 112, member ...
    31(a)
    30(a)
    many ↔ many
    many ↔ many
    15(5202740-5204422) ENSDARG00000077146
    15(5221640-5223327) ENSDARG00000077211


    ENSEMBL Gene Tree for OR51E2 (if available)
    TreeFam Gene Tree for OR51E2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OR51E2 gene
    OR51M12  OR51D12  OR51V12  OR51B62  OR51B52  OR51J12  OR51Q12  OR51B42  
    OR51B22  OR51E12  
    Selected SIMAP similar genes for OR51E2 using alignment to 2 protein entries:     O51E2_HUMAN (see all proteins) (see all similar genes):
    OR51E1    OR51D1    OR51G2    OR52K1    OR52K2    OR51A4
    OR51A2    OR51G1    OR51A7    OR51F2    OR52J3    OR52M1
    OR51B6    OR51H1P    OR51L1    OR51V1    OR52D1    OR52L1

    Find genes that share paralogs with OR51E2           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for OR51E2
    PGOHUM00000257871


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OR51E2 (see all 483)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1424865611,2
    C--4701486(+) GGTACA/GGAGCA 1 -- ut310--------
    rs16851,2
    C,F,O,H--4701510(+) AGACAT/CGATCA 1 -- ut31 ese315Minor allele frequency- C:0.05MN NA NS EA 1294
    rs1471729701,2
    --4701585(+) GATCAC/TGAAAG 1 -- ut310--------
    rs22921571,2
    C,F,O,H--4701586(-) CCTTTC/TGTGAT 1 -- ut3114Minor allele frequency- N:0.00EA NA NS WA 2468
    rs1403666241,2
    --4701625(+) TGTTGC/TCCACA 1 -- ut310--------
    rs1859057921,2
    --4701737(+) GATGTA/TACACA 1 -- ut310--------
    rs1455942661,2
    C--4701825(+) AAGCCA/GTGTGA 1 -- ut310--------
    rs1899750101,2
    --4701894(+) ATGGTA/GCCTAC 1 -- ut310--------
    rs1812699671,2
    --4701912(+) AGTTAC/TGAAGA 1 -- ut310--------
    rs71118831,2
    C,F,A,H--4701913(+) gttacG/Aaagaa 1 -- ut31 ese318Minor allele frequency- A:0.10NS EA NA WA 2342

    HapMap Linkage Disequilibrium report for OR51E2 ( 4702982 - 4703941 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for OR51E2:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv896916CNV Loss21882294
    nsv832055CNV Loss17160897
    nsv896911CNV Gain21882294
    nsv832056CNV Gain17160897
    nsv896915CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OR51E2
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611268    OMIM disorders: --

    1 disease for OR51E2:    
    About MalaCards
    prostate cancer


    Find genes that share disorders with OR51E2           About GenesLikeMe

    2 Novoseek inferred disease relationships for OR51E2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 54.6 43 11118034 (4), 15499628 (4), 16491480 (3), 16149059 (3) (see all 6)
    tumors 8.26 18 11118034 (4), 15499628 (3), 16149059 (1)


    Export disorders for OR51E2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OR51E2 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with OR51E2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. PSGR, a novel prostate-specific gene with homology to a G protein- coupled receptor, is overexpressed in prostate cancer. (PubMed id 11118034)1, 2, 3, 9 Xu L.L.... Srivastava S. (Cancer Res. 2000)
    2. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl- CoA racemase. (PubMed id 16491480)1, 2, 9 Wang J.... Ittmann M. (Prostate 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    5. Cloning and genetic characterization of an evolutionarily conserved human olfactory receptor that is differentially expressed across species. (PubMed id 11707321)1, 2 Yuan T.T....Kretschmer P.J. (Gene 2001)
    6. Regulation of human prostate-specific G-protein coupled receptor, PSGR, by two distinct promoters and growth factors. (PubMed id 16149059)1, 9 Weng J....Liu M. (J. Cell. Biochem. 2005)
    7. Increased expression of prostate-specific G-protein-coupled receptor in human prostate intraepithelial neoplasia and prostate cancers. (PubMed id 15499628)1, 9 Weng J....Liu M. (Int. J. Cancer 2005)
    8. Activation of an olfactory receptor inhibits proliferation of prostate cancer cells. (PubMed id 19389702)1, 9 Neuhaus E.M....Hatt H. (J. Biol. Chem. 2009)
    9. Identification of a prostate-specific G-protein coupled receptor in prostate cancer. (PubMed id 11593396)1, 9 Xia C....Liu M. (Oncogene 2001)
    10. Quantitative expression profile of PSGR in prostate cancer. (PubMed id 16231015)1 Xu L.L....Srivastava S. (Prostate Cancer Prostatic Dis. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
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      Query String
    PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81285 HGNC: 15195 AceView: OR51E2 Ensembl:ENSG00000167332 euGenes: HUgn81285
    ECgene: OR51E2 Kegg: 81285 H-InvDB: OR51E2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OR51E2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for OR51E2 Genetics and Cytogenetics in Oncology and Haematology
    HORDE entry for OR51E2 The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OR51E2 gene:
    Search GeneIP for patents involving OR51E2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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