Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



OR51E1 Gene

protein-coding   GIFtS: 56
GCID: GC11P004622

Olfactory Receptor, Family 51, Subfamily E, Member 1

(Previous names: olfactory receptor, family 51, subfamily E, member 1 pseudogene)
(Previous symbols: OR51E1P, OR52A3P, GPR164)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Olfactory Receptor, Family 51, Subfamily E, Member 11 2     POGR2 3
GPR1641 2 3     G-Protein Coupled Receptor 1642 3
OR51E1P1 2 3     DGPCR2 5
OR52A3P1 2 3     GPR1362
PSGR22 3 5     Dresden-G-Protein-Coupled Receptor2
Olfactory Receptor, Family 51, Subfamily E, Member 1 Pseudogene1 2     Olfactory Receptor 51E12
Olfactory Receptor 52A32 3     Olfactory Receptor OR11-152
Prostate-Overexpressed G Protein-Coupled Receptor2 3     Olfactory Receptor, Family 52, Subfamily A, Member 3 Pseudogene2
Prostate-Specific G Protein-Coupled Receptor 22 3     Prostate Overexpressed G Protein-Coupled Receptor2
D-GPCR2 3     

External Ids:    HGNC: 151941   Entrez Gene: 1435032   Ensembl: ENSG000001807857   OMIM: 6112675   UniProtKB: Q8TCB63   

Export aliases for OR51E1 gene to outside databases

Previous GC identifers: GC11U990519 GC00U920624


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for OR51E1 Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for OR51E1 Gene:
OR51E1 (olfactory receptor, family 51, subfamily E, member 1) is a protein-coding gene. Diseases associated with OR51E1 include neuroendocrine carcinoma, and familial colorectal cancer. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51M1.

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
Function: Odorant receptor (Potential)

Gene Wiki entry for OR51E1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000011.10  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the OR51E1 gene promoter:
         HOXA9   HOXA9B   AML1a   SREBP-1c   CUTL1   SREBP-1b   Evi-1   Meis-1b   SREBP-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOR51E1 promoter sequence
   Search Chromatin IP Primers for OR51E1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR51E1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

OR51E1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OR51E1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P004622:  view genomic region     (about GC identifiers)

Start:
4,673,757 bp from pter      End:
4,674,710 bp from pter
Size:
954 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6 (See protein sequence)
Recommended Name: Olfactory receptor 51E1  
Size: 317 amino acids; 35271 Da
Sequence caution: Sequence=AAU07996.1; Type=Erroneous initiation; Sequence=DAA04767.1; Type=Erroneous initiation;
Secondary accessions: A8KAM6 Q5S4P5 Q66X57 Q6IF93

Explore the universe of human proteins at neXtProt for OR51E1: NX_Q8TCB6

Explore proteomics data for OR51E1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn7, Asn90
  • HORDE protein sequence for OR51E1

    See OR51E1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689643.2  
    ENSEMBL proteins: 
     ENSP00000380155   ENSP00000431593  
    Reactome Protein details: Q8TCB6

    OR51E1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for OR51E1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for OR51E1
    GenScript Custom Purified and Recombinant Proteins Services for OR51E1
    Novus Biologicals OR51E1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OR51E1

    OR51E1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for OR51E1
    OriGene Custom Antibody Services for OR51E1
    Novus Biologicals OR51E1 Antibodies
    Abcam antibodies for OR51E1
    Cloud-Clone Corp. Antibodies for OR51E1
    ThermoFisher Antibodies for OR51E1
    LSBio Antibodies in human, mouse, rat for OR51E1

    OR51E1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for OR51E1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for OR51E1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for OR51E1
    Cloud-Clone Corp. CLIAs for OR51E1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    OR51: GPCR / Class A : Olfactory receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: OR51E1
    Other 7TM proteins

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000725 Olfact_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q8TCB6

    ProtoNet protein and cluster: Q8TCB6

    1 Blocks protein domain: IPB000725 Olfactory receptor signature

    UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
    Similarity: Belongs to the G-protein coupled receptor 1 family


    OR51E1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: O51E1_HUMAN, Q8TCB6
    Function: Odorant receptor (Potential)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0004984olfactory receptor activity IEA--
         
    OR51E1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OR51E1:
     Decreased Salmonella enterica  

         1 MGI phenotypic allele for Olfr558 (no phenotypes)

    OR51E1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Olfr558tm1Lex for OR51E1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OR51E1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OR51E1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OR51E1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OR51E1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat OR51E1 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate OR51E1:
    hsa-miR-505 hsa-miR-3161 hsa-miR-875-3p hsa-miR-9* hsa-miR-589* hsa-miR-888*
    SwitchGear 3'UTR luciferase reporter plasmidOR51E1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for OR51E1
    Predesigned siRNA for gene silencing in human, mouse, rat OR51E1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for OR51E1

    Clone
    Products:
         
    OriGene clones in human, mouse for OR51E1 (see all 8)
    OriGene ORF clones in mouse, rat for OR51E1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OR51E1 (NM_152430)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51E1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for OR51E1
    Browse ESI BIO Cell Lines and PureStem Progenitors for OR51E1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    O51E1_HUMAN, Q8TCB6: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    OR51E1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for OR51E1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Olfactory Signaling Pathway
    Olfactory Signaling Pathway0.82
    Olfactory transduction0.82
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for OR51E1
        Olfactory Signaling Pathway


    1 Kegg Pathway  (Kegg details for OR51E1):
        Olfactory transduction


    OR51E1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OR51E1
    Interactions:

        Search GeneGlobe Interaction Network for OR51E1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for OR51E1 (ENSP000003801554) via UniProtKB, MINT, STRING, and/or I2D (see all 273)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OR52E6ENSP000003288784STRING: ENSP00000369279 STRING: ENSP00000328878
    OR1D2ENSP000003275854STRING: ENSP00000327585
    OR2C1ENSP000003077264STRING: ENSP00000307726
    OR2Y1ENSP000003124034STRING: ENSP00000312403
    OR4E2ENSP000003861954STRING: ENSP00000386195
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----

    OR51E1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OR51E1 (O51E1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for OR51E1 gene: 
    NM_152430.3  

    Unigene Cluster for OR51E1:

    Olfactory receptor, family 51, subfamily E, member 1
    Hs.470038  [show with all ESTs]
    Unigene Representative Sequence: NM_152430
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396952(uc001lzi.4) ENST00000530215
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat OR51E1 using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate OR51E1:
    hsa-miR-505 hsa-miR-3161 hsa-miR-875-3p hsa-miR-9* hsa-miR-589* hsa-miR-888*
    SwitchGear 3'UTR luciferase reporter plasmidOR51E1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OR51E1
    Predesigned siRNA for gene silencing in human, mouse, rat OR51E1
    Clone
    Products:
         
    OriGene clones in human, mouse for OR51E1 (see all 8)
    OriGene ORF clones in mouse, rat for OR51E1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OR51E1 (NM_152430)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51E1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OR51E1
    OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OR51E1
      QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
      QuantiFast Probe-based Assays in human, mouse, rat OR51E1

    Additional mRNA sequence: 

    AK023643.1 AK293091.1 AL833127.1 AY698056.1 AY775731.1 BC022401.1 

    2 DOTS entries:

    DT.204079  DT.92068565 

    Selected AceView cDNA sequences (see all 31):

    BX092732 AA988520 AI457247 BX283988 NM_152430 AW235635 BC022401 BE550795 
    BF433082 AY698056 AA622418 AI631017 BG212555 BP341178 AU138663 AK023643 
    AW138131 AL833127 AI871596 BF002049 AW771398 AA689245 BG541042 AI694767 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    OR51E1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGCCACACA
    OR51E1 Expression
    About this image

    OR51E1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OR51E1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.470038

    UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
    Tissue specificity: Highly expressed in prostate. Very low levels may be detected in some other tissues, such as
    placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers

        Custom PCR Arrays for OR51E1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for OR51E1
    OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OR51E1
    QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
    QuantiFast Probe-based Assays in human, mouse, rat OR51E1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for OR51E1 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Olfr5581 , 5 olfactory receptor 5581, 5 87.87(n)1
    93.67(a)1
      7 (54.81 cM)5
    2590971  NM_147093.31  NP_667304.11 
     1027023315 
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01018874.16
    or112-16
    Uncharacterized protein
    odorant receptor, family A, subfamily 112, member ...
    32(a)
    31(a)
    many ↔ many
    many ↔ many
    15(5202740-5204422) ENSDARG00000077146
    15(5221640-5223327) ENSDARG00000077211


    ENSEMBL Gene Tree for OR51E1 (if available)
    TreeFam Gene Tree for OR51E1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for OR51E1 gene
    OR51M12  OR51D12  OR51V12  OR51B62  OR51B52  OR51J12  OR51Q12  OR51E22  
    OR51B42  OR51B22  
    Selected SIMAP similar genes for OR51E1 using alignment to 2 protein entries:     O51E1_HUMAN (see all proteins) (see all similar genes):
    OR51E2    OR51D1    OR51G2    OR51G1    OR52M1    OR51A4
    OR51A7    OR52A1    OR52J3    OR51A2    OR51F2    OR51H1P
    OR51L1    OR52D1    OR52E4    OR52N5    OR51I2    OR52A5

    OR51E1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for OR51E1 (see all 369)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs346990241,2
    C--4587198(+) AAAAA-/A/A   
       A
    /AAA
    GCCTT
    2 -- us2k1 cds11NA 2
    rs1826120041,2
    --4663179(+) TGACAC/TGAATG 1 -- us2k10--------
    rs800870211,2
    C--4663374(+) CAGAAA/TGAAAG 1 -- us2k10--------
    rs769089561,2
    C--4663376(+) GAATGA/CAAGGA 1 -- us2k10--------
    rs1876232921,2
    --4663380(+) GAAAGA/GAAACA 1 -- us2k10--------
    rs169237911,2
    C,F,H--4663479(+) CCTACG/ATTTCC 1 -- us2k122Minor allele frequency- A:0.18NA NS EA WA CSA 2033
    rs1442817361,2
    C--4663498(+) CTATCC/TGAGGC 1 -- us2k10--------
    rs107681391,2
    C,F,A,H--4663543(+) TAGCAA/GGTCAT 1 -- us2k134Minor allele frequency- N:0.00EA NA NS CSA WA 3401
    rs740524811,2
    C,F--4663644(+) TTAGCC/TGGGTG 1 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1115452871,2
    C,F--4663659(+) GGCGCG/ATGCCT 1 -- us2k12Minor allele frequency- A:0.04NA 122

    HapMap Linkage Disequilibrium report for OR51E1 ( 4673757 - 4674710 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for OR51E1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2670201CNV Deletion23128226
    nsv832055CNV Loss17160897
    nsv896911CNV Gain21882294
    nsv832056CNV Gain17160897
    nsv896915CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OR51E1
    DNA2.0 Custom Variant and Variant Library Synthesis for OR51E1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 611267    OMIM disorders: --

    6 diseases for OR51E1:    About MalaCards
    neuroendocrine carcinoma    familial colorectal cancer    prostatitis    colorectal cancer
    prostate cancer    neuronitis

    1 disease from the University of Copenhagen DISEASES database for OR51E1:
    Neuroendocrine carcinoma

    OR51E1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): OR51E1
    Human Genome Epidemiology (HuGE) Navigator: OR51E1 (2 documents)

    Export disorders for OR51E1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for OR51E1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with OR51E1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. (PubMed id 16206286)1, 2 Weng J.... Liu M. (Int. J. Cancer 2006)
    2. D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate. (PubMed id 15313197)1, 2 Weigle B....Rieber E.P. (Biochem. Biophys. Res. Commun. 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004)
    6. Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas. (PubMed id 23184910)1 Cui T....Giandomenico V. (Eur. J. Endocrinol. 2013)
    7. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)4 Levy D....Mitchell G.F. (BMC Med. Genet. 2007)
    8. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl- CoA racemase. (PubMed id 16491480)1 Wang J.... Ittmann M. (Prostate 2006)
    9. Novel human G-protein-coupled receptors. (PubMed id 12732197)1 Vanti W.B....O'Dowd B.F. (Biochem. Biophys. Res. Commun. 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 143503 HGNC: 15194 AceView: OR51E1P Ensembl:ENSG00000180785 euGenes: HUgn143503
    ECgene: OR51E1 Kegg: 143503 H-InvDB: OR51E1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for OR51E1 Pharmacogenomics, SNPs, Pathways
    HORDE entry for OR51E1 The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for OR51E1 gene:
    Search GeneIP for patents involving OR51E1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for OR51E1   OriGene RNAi products in human, mouse, rat for OR51E1  
     OriGene qPCR primer pairs and template standards for OR51E1   OriGene Protein Over-expression Lysate for OR51E1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for OR51E1  
     OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for OR51E1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for OR51E1   OriGene Custom Protein Services for OR51E1  

     
     
     Block miRNA regulation of human, mouse, rat OR51E1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing OR51E1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OR51E1 Predesigned siRNA for gene silencing in human, mouse, rat OR51E1
     QuantiFast Probe-based Assays in human, mouse, rat OR51E1 QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
     Custom PCR Arrays for OR51E1 Search Chromatin IP Primers for OR51E1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OR51E1  Search GeneGlobe Interaction Network for OR51E1
     Regulatory tfbs in OR51E1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for OR51E1 GenScript cDNA clones with any tag delivered in your preferred vector for OR51E1
     GenScript Custom Assay Services for OR51E1 GenScript Custom overexpressing Cell Line Services for OR51E1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for OR51E1 (O51E1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     OR51E1 antibodies
     OR51E1 lysates
     Antibodies for OR51E1
     See all of Abcam's Antibodies, Kits and Proteins for OR51E1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for OR51E1
     Antibodies for OR51E1
     ELISAs for OR51E1
     CLIAs for OR51E1



     Browse ESI BIO Cell Lines and PureStem Progenitors for OR51E1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1
     SwitchGear 3'UTR luciferase reporter plasmids for OR51E1
     SwitchGear Promoter luciferase reporter plasmids for OR51E1
     ThermoFisher Antibodies for OR51E1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OR51E1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OR51E1
     LSBio Antibodies in human, mouse, rat for OR51E1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      OR51E1 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4