Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OR51E1 Gene

protein-coding   GIFtS: 56
GCID: GC11P004622

Olfactory Receptor, Family 51, Subfamily E, Member 1

(Previous names: olfactory receptor, family 51, subfamily E, member 1 pseudogene)
(Previous symbols: OR51E1P, OR52A3P, GPR164)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Olfactory Receptor, Family 51, Subfamily E, Member 11 2     PSGR22 3
GPR1641 2 3     G-Protein Coupled Receptor 1642 3
OR51E1P1 2 3     DGPCR2
OR52A3P1 2 3     GPR1362
Olfactory Receptor, Family 51, Subfamily E, Member 1 Pseudogene1 2     Dresden-G-Protein-Coupled Receptor2
Olfactory Receptor 52A32 3     Olfactory Receptor 51E12
Prostate-Overexpressed G Protein-Coupled Receptor2 3     Olfactory Receptor OR11-152
Prostate-Specific G Protein-Coupled Receptor 22 3     Olfactory Receptor, Family 52, Subfamily A, Member 3 Pseudogene2
D-GPCR2 3     Prostate Overexpressed G Protein-Coupled Receptor2
POGR2 3     

External Ids:    HGNC: 151941   Entrez Gene: 1435032   Ensembl: ENSG000001807857   OMIM: 6112675   UniProtKB: Q8TCB63   

Export aliases for OR51E1 gene to outside databases

Previous GC identifers: GC11U990519 GC00U920624


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OR51E1 Gene:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the
perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled
receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain
structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G
protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the
genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent
of other organisms. (provided by RefSeq, Jul 2008)

GeneCards Summary for OR51E1 Gene: 
OR51E1 (olfactory receptor, family 51, subfamily E, member 1) is a protein-coding gene. Diseases associated with OR51E1 include familial colorectal cancer, and prostatitis, and among its related super-pathways are Olfactory Signaling Pathway and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR51D1.

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
Function: Odorant receptor (Potential)

Gene Wiki entry for OR51E1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OR51E1 gene promoter:
         HOXA9   HOXA9B   AML1a   SREBP-1c   CUTL1   SREBP-1b   Evi-1   Meis-1b   SREBP-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOR51E1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OR51E1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR51E1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

OR51E1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OR51E1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P004622:  view genomic region     (about GC identifiers)

Start:
4,673,757 bp from pter      End:
4,674,710 bp from pter
Size:
954 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6 (See protein sequence)
Recommended Name: Olfactory receptor 51E1  
Size: 317 amino acids; 35271 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAU07996.1; Type=Erroneous initiation; Sequence=DAA04767.1; Type=Erroneous initiation;
Secondary accessions: A8KAM6 Q5S4P5 Q66X57 Q6IF93

Explore the universe of human proteins at neXtProt for OR51E1: NX_Q8TCB6

Explore proteomics data for OR51E1 at MOPED 

HORDE protein sequence for OR51E1
OR51E1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

OR51E1 Protein Expression

REFSEQ proteins: NP_689643.2  
ENSEMBL proteins: 
 ENSP00000380155   ENSP00000431593  
Reactome Protein details: Q8TCB6
Human Recombinant Protein Products for OR51E1: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for OR51E1
OriGene Custom MassSpec 
OriGene Custom Protein Services for OR51E1
GenScript Custom Purified and Recombinant Proteins Services for OR51E1
Novus Biologicals OR51E1 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for OR51E1 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0016021integral to membrane IEA--

OR51E1 for ontologies           About GeneDecksing



OR51E1 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
OriGene Antibodies for OR51E1
OriGene Custom Antibody Services for OR51E1
GenScript Custom Superior Antibodies Services for OR51E1
Novus Biologicals OR51E1 Antibodies
Abcam antibodies for OR51E1
Cloud-Clone Corp. Antibodies for OR51E1 
ThermoFisher Antibodies for OR51E1
LSBio Antibodies in human, mouse, rat for OR51E1 

Assay Products for OR51E1: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for OR51E1
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for OR51E1
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for OR51E1 
Cloud-Clone Corp. CLIAs for OR51E1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
OR51: GPCR / Class A : Olfactory receptors

IUPHAR Guide to PHARMACOLOGY protein family classification: OR51E1 
Other 7TM proteins

3 InterPro protein domains:
 IPR017452 GPCR_Rhodpsn_7TM
 IPR000725 Olfact_rcpt
 IPR000276 GPCR_Rhodpsn

Graphical View of Domain Structure for InterPro Entry Q8TCB6

ProtoNet protein and cluster: Q8TCB6

1 Blocks protein domain: IPB000725 Olfactory receptor signature

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
Similarity: Belongs to the G-protein coupled receptor 1 family


OR51E1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: O51E1_HUMAN, Q8TCB6
Function: Odorant receptor (Potential)

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004930G-protein coupled receptor activity IEA--
GO:0004984olfactory receptor activity IEA--
     
OR51E1 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for OR51E1:
 Decreased Salmonella enterica  

     1 MGI phenotypic allele for Olfr558 (no phenotypes)

OR51E1 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Olfr558tm1Lex for OR51E1

   inGenious Targeting Laboratory - Custom generated mouse model solutions for OR51E1 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OR51E1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OR51E1 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OR51E1 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OR51E1
6 QIAGEN miScript miRNA Assays for microRNAs that regulate OR51E1:
hsa-miR-505 hsa-miR-3161 hsa-miR-875-3p hsa-miR-9* hsa-miR-589* hsa-miR-888*
SwitchGear 3'UTR luciferase reporter plasmidOR51E1 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for OR51E1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR51E1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for OR51E1
Sirion Biotech Customized adenovirus for overexpression of OR51E1

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for OR51E1 (see all 9)
OriGene ORF clones in mouse, rat for OR51E1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: OR51E1 (NM_152430)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51E1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1
Sirion Biotech Customized lentivirus for stable overexpression of OR51E1 
                     Customized lentivirus expression plasmids for stable overexpression of OR51E1 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for OR51E1
Search LifeMap BioReagents cell lines for OR51E1
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for OR51E1 About                                                                                                See pathways by source

SuperPathContained pathways About
1Olfactory transduction
Olfactory Signaling Pathway0.81
Olfactory transduction0.81
2Signaling by GPCR
Signaling by GPCR0.90
Signal Transduction0.55
GPCR downstream signaling0.90

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


4        Reactome Pathways for OR51E1
    GPCR downstream signaling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR


1         Kegg Pathway  (Kegg details for OR51E1):
    Olfactory transduction


OR51E1 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OR51E1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/273 Interacting proteins for OR51E1 (ENSP000003801554) via UniProtKB, MINT, STRING, and/or I2D (see all 273)
InteractantInteraction Details
GeneCardExternal ID(s)
OR52E6ENSP000003288784STRING: ENSP00000369279 STRING: ENSP00000328878
OR1D2ENSP000003275854STRING: ENSP00000327585
OR51E2ENSP000003801534STRING: ENSP00000380153
GNALENSP000003340514STRING: ENSP00000334051
GNGT1ENSP000002485724STRING: ENSP00000248572
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007186G-protein coupled receptor signaling pathway ----

OR51E1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OR51E1 (O51E1)

Search CenterWatch for drugs/clinical trials and news about OR51E1 / O51E1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for OR51E1 gene: 
NM_152430.3  

Unigene Cluster for OR51E1:

Olfactory receptor, family 51, subfamily E, member 1
Hs.470038  [show with all ESTs]
Unigene Representative Sequence: NM_152430
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000396952(uc001lzi.4) ENST00000530215
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OR51E1
6 QIAGEN miScript miRNA Assays for microRNAs that regulate OR51E1:
hsa-miR-505 hsa-miR-3161 hsa-miR-875-3p hsa-miR-9* hsa-miR-589* hsa-miR-888*
SwitchGear 3'UTR luciferase reporter plasmidOR51E1 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for OR51E1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR51E1
Clone
Products:
     
OriGene clones in human, mouse for OR51E1 (see all 9)
OriGene ORF clones in mouse, rat for OR51E1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: OR51E1 (NM_152430)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for OR51E1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1
Sirion Biotech Customized lentivirus for stable overexpression of OR51E1 
                     Customized lentivirus expression plasmids for stable overexpression of OR51E1 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for OR51E1
OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OR51E1
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR51E1

Additional mRNA sequence: 

AK023643.1 AK293091.1 AL833127.1 AY698056.1 AY775731.1 BC022401.1 

2 DOTS entries:

DT.204079  DT.92068565 

24/31 AceView cDNA sequences (see all 31):

AW235635 BC022401 BX283988 BX092732 AA988520 AI457247 NM_152430 BE550795 
BF433082 BF002049 BG212555 AI871596 AU138663 AL833127 AI631017 BP341178 
AK023643 AY698056 AW138131 AW771398 AA622418 AA531196 BF674130 AI694767 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OR51E1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TGGCCACACA
OR51E1 Expression
About this image


See OR51E1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OR51E1

SOURCE GeneReport for Unigene cluster: Hs.470038

UniProtKB/Swiss-Prot: O51E1_HUMAN, Q8TCB6
Tissue specificity: Highly expressed in prostate. Very low levels may be detected in some other tissues, such as
placenta, skeletal muscle, heart, ovary and testis. Up-regulated in prostate cancers

    SABiosciences Custom PCR Arrays for OR51E1
Primer
Products:
OriGene qPCR primer pairs and template standards for OR51E1
OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OR51E1
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR51E1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for OR51E1 gene from 1/7 species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Olfr5581 , 5 olfactory receptor 5581, 5 87.87(n)1
93.67(a)1
  7 (54.81 cM)5
2590971  NM_147093.31  NP_667304.11 
 1027023315 


ENSEMBL Gene Tree for OR51E1 (if available)
TreeFam Gene Tree for OR51E1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for OR51E1 gene
OR51D12  OR51V12  OR51B52  OR51B62  OR51J12  OR51E22  OR51Q12  OR51B42  
OR51B22  
18/427 SIMAP similar genes for OR51E1 using alignment to 2 protein entries:     O51E1_HUMAN (see all proteins) (see all similar genes):
OR51E2    OR51D1    OR51G2    OR51G1    OR52M1    OR51A4
OR51A7    OR52A1    OR52J3    OR51A2    OR51F2    OR51H1P
OR51L1    OR52D1    OR52E4    OR52N5    OR51I2    OR52A5

OR51E1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/369 SNPs in OR51E1 are shown (see all 369)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs346990241,2
C--4587198(+) AAAAA-/A/A   
   A
/AAA
GCCTT
2 -- us2k1 cds11NA 2
rs1826120041,2
--4663179(+) TGACAC/TGAATG 1 -- us2k10--------
rs800870211,2
C--4663374(+) CAGAAA/TGAAAG 1 -- us2k10--------
rs769089561,2
C--4663376(+) GAATGA/CAAGGA 1 -- us2k10--------
rs1876232921,2
--4663380(+) GAAAGA/GAAACA 1 -- us2k10--------
rs169237911,2
C,F,H--4663479(+) CCTACG/ATTTCC 1 -- us2k122Minor allele frequency- A:0.18NA NS EA WA CSA 2033
rs1442817361,2
C--4663498(+) CTATCC/TGAGGC 1 -- us2k10--------
rs107681391,2
C,F,A,H--4663543(+) TAGCAA/GGTCAT 1 -- us2k134Minor allele frequency- N:0.00EA NA NS CSA WA 3401
rs740524811,2
C,F--4663644(+) TTAGCC/TGGGTG 1 -- us2k11Minor allele frequency- T:0.50WA 2
rs1115452871,2
C,F--4663659(+) GGCGCG/ATGCCT 1 -- us2k12Minor allele frequency- A:0.04NA 122

HapMap Linkage Disequilibrium report for OR51E1 ( 4673757 - 4674710 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for OR51E1:    About this table     
Variant IDTypeSubtypePubMed ID
esv2670201CNV Deletion23128226
nsv832055CNV Loss17160897
nsv896911CNV Gain21882294
nsv832056CNV Gain17160897
nsv896915CNV Gain21882294

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing OR51E1
DNA2.0 Custom Variant and Variant Library Synthesis for OR51E1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 611267    OMIM disorders: --

6 diseases for OR51E1:    About MalaCards
familial colorectal cancer    prostatitis    neuroendocrine carcinoma    colorectal cancer
prostate cancer    neuronitis

1 disease from the University of Copenhagen DISEASES database for OR51E1:
Neuroendocrine carcinoma

OR51E1 for disorders           About GeneDecksing

Genetic Association Database (GAD): OR51E1
Human Genome Epidemiology (HuGE) Navigator: OR51E1 (2 documents)

Export disorders for OR51E1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for OR51E1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with OR51E1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. PSGR2, a novel G-protein coupled receptor, is overexpressed in human prostate cancer. (PubMed id 16206286)1, 2 Weng J.... Liu M. (2006)
  2. D-GPCR: a novel putative G protein-coupled receptor overexpressed in prostate cancer and prostate. (PubMed id 15313197)1, 2 Weigle B....Rieber E.P. (2004)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
  5. The human olfactory receptor gene family. (PubMed id 14983052)1, 2 Malnic B.... Buck L.B. (2004)
  6. Olfactory receptor 51E1 protein as a potential novel t issue biomarker for small intestine neuroendocrine carcinomas. (PubMed id 23184910)1 Cui T....Giandomenico V. (2013)
  7. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)4 Levy D....Mitchell G.F. (2007)
  8. The prostate-specific G-protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to alpha-methylacyl-CoA racemase. (PubMed id 16491480)1 Wang J....Ittmann M. (2006)
  9. Novel human G-protein-coupled receptors. (PubMed id 12732197)1 Vanti W.B....O'Dowd B.F. (2003)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 143503 HGNC: 15194 AceView: OR51E1P Ensembl:ENSG00000180785 euGenes: HUgn143503
ECgene: OR51E1 Kegg: 143503 H-InvDB: OR51E1

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for OR51E1 Pharmacogenomics, SNPs, Pathways
HORDE entry for OR51E1 The Human Olfactory Receptor Data Explorer at the Weizmann Institute of Science

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for OR51E1 gene:
Search GeneIP for patents involving OR51E1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 OriGene Antibodies for OR51E1   OriGene RNAi products in human, mouse, rat for OR51E1  
 OriGene qPCR primer pairs and template standards for OR51E1   OriGene Protein Over-expression Lysate for OR51E1  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for OR51E1  
 OriGene qSTAR qPCR primer pairs in human, mouse for OR51E1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for OR51E1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for OR51E1   OriGene Custom Protein Services for OR51E1  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OR51E1
 QIAGEN SeqTarget long-range PCR primers for resequencing OR51E1
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OR51E1
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OR51E1
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OR51E1
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OR51E1
 GenScript Custom Purified and Recombinant Proteins Services for OR51E1 GenScript cDNA clones with any tag delivered in your preferred vector for OR51E1
 GenScript Custom Assay Services for OR51E1 GenScript Custom Superior Antibodies Services for OR51E1
 GenScript Custom overexpressing Cell Line Services for OR51E1 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in OR51E1 promoter
 Search Chromatin IP Primers for OR51E1
 RT2 qPCR Primer Assay in human, mouse, rat OR51E1
 Search GNC Networks for OR51E1
 SABiosciences Custom PCR Arrays for OR51E1
 Search Tocris compounds for OR51E1 (O51E1)
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 OR51E1 antibodies
 OR51E1 lysates
 Antibodies for OR51E1
 See all of Abcam's Antibodies, Kits and Proteins for OR51E1
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for OR51E1
 Antibodies for OR51E1
 ELISAs for OR51E1
 CLIAs for OR51E1
 Search LifeMap BioReagents cell lines for OR51E1
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OR51E1
 SwitchGear 3'UTR luciferase reporter plasmids for OR51E1
 SwitchGear Promoter luciferase reporter plasmids for OR51E1
 ThermoFisher Antibodies for OR51E1
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OR51E1
 inGenious Targeting Laboratory - Custom generated mouse model solutions for OR51E1
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OR51E1
Customized:
 lentivirus for stable overexpression of OR51E1
 lentivirus expression plasmids for stable overexpression of OR51E1
 adenovirus for overexpression of OR51E1
 LSBio Antibodies in human, mouse, rat for OR51E1
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      OR51E1 gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4